Coligyl-4.5 MIU Injection belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Coligyl-4.5 MIU Injection contains Colistimethate Sodium. Colistimethate Sodium effectively solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Coligyl-4.5 MIU Injection destroys the bacteria and successfully treats the infection.

Coligyl-4.5 MIU Injection will be administered by a qualified healthcare professional. Sometimes, you may experience common side effects like injection site reactions, renal damage, visual disturbances, GI disturbances, dizziness, nausea, vomiting and muscle weakness. But these side effects are usually in the initial phase and resolve over time. However, if these side effects persist, let your doctor know.

Before receiving Coligyl-4.5 MIU Injection, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Coligyl-4.5 MIU Injection can cause blurred vision and dizziness in some people; if this occurs, do not drive or operate tools or machinery. It is recommended not to consume any alcoholic beverages while on treatment with this medicine.

Coligyl-4.5 MIU Injection contains Colistimethate Sodium. Colistimethate Sodium, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram-negative infections. Colistimethate Sodium essentially solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Coligyl-4.5 MIU Injection kills the bacteria and effectively treats the infection. In addition, it can also treat infectious diarrhoea and urinary tract infections.

• Superinfection (reinfection)
• Renal damage
• Visual disturbances
• GI disturbances
• Dizziness
• Nausea
• Vomiting
• Confusion
• Peripheral neuropathy
• Respiratory insufficiency
• Muscle weakness

If you are allergic to Coligyl-4.5 MIU Injection, please inform your physician. Inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Inform your doctor if you are pregnant, planning to become pregnant, or are breastfeeding before receiving Coligyl-4.5 MIU Injection. Also, inform your doctor if you have chronic kidney disease, myasthenia gravis (muscle disorder), and porphyria (a blood disorder). Do not abruptly discontinue taking the prescription since this may result in antibiotic resistance, a condition in which bacteria develop resistance to antibiotics.

Drug-Drug Interactions: Coligyl-4.5 MIU Injection is known to interact with selective skeletal muscle relaxants (e.g. cyclobenzaprine, metaxalone), antifungals (e.g. amphotericin B) and aminoglycosides (e.g. capreomycin, vancomycin)

Drug-Food Interactions: Coligyl-4.5 MIU Injection is known to interact with alcohol and Grapefruit.

Drug-Disease Interactions: Coligyl-4.5 MIU Injection is known to interact with disease conditions, including kidney problems, myasthenia gravis (a muscle disorder), and porphyria (a blood disorder).

• CYCLOBENZAPRINE
• METAXALONE
• AMPHOTERICIN B
• CAPREOMYCIN
• VANCOMYCIN

• After taking the full course of Coligyl-4.5 MIU Injection, probiotics should be taken to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can restore the intestine's good bacteria stink.
• Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
• Avoid taking many calcium-enriched foods and drinks as it might affect the working of Coligyl-4.5 MIU Injection.
• Avoid intake of alcoholic beverages with Coligyl-4.5 MIU Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Coligyl-4.5 MIU Injection in fighting off infections.

• Regular blood tests are required to monitor kidney functions while taking Coligyl-4.5 MIU Injection.
• A Healthcare professional should always give a Coligyl-4.5 MIU Injection to a hospital. Never self-administer.

Bacterial infections: A bacterial infection occurs when harmful bacteria enter the body, multiply, and infect it. It may attack any region of the body and multiply swiftly. Fever, chills, and tiredness are common symptoms. Bacteria come in a variety of shapes, including spherical, rod, and spiral-shaped bacteria. Bacterial infections range in severity from simple ailments such as sore throats and ear infections to serious brain infections such as meningitis and encephalitis. A bacterial infection can infect anyone at any time. People with a weakened immune system or who are on immunosuppressive medications, on the other hand, are more vulnerable to bacterial infection.