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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:37 PM IST
Coftos Syrup is a combination medicine which belongs to the class of expectorants. It is used in the treatment of cough. This medicine works by inhibiting the chemical substance, histamine which is responsible for cough. It helps loosen the congestion in the chest and throat by decreasing airway secretion's stickiness. Common side effects include headache, dizziness, nausea, fatigue, restlessness, and dry mouth.
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About Coftos Syrup

Coftos Syrup is used to provide relief from cough. Coughing (dry or productive) is a body's way of clearing irritants (like allergens, mucus, or smoke) from airways thereby preventing respiratory infection. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract.

Coftos Syrup is a combination of three drugs, namely: Ammonium chloride (expectorant), Chlorpheniramine maleate (antihistamine), and Sodium citrate (mucolytic). Ammonium chloride helps loosen the congestion in the chest and throat by decreasing airway secretion's stickiness. Chlorpheniramine maleate works by blocking a chemical substance called histamine, which is responsible for causing allergic reactions. Sodium citrate loosens and thins the phlegm, making it easier to cough out. Together, Coftos Syrup provides relief from cough. 

You are advised to take Coftos Syrup for as long as your doctor has prescribed it for you depending on your medical condition. Coftos Syrup may cause certain common side-effects such as headache, dizziness, nausea, fatigue, and dry mouth in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Coftos Syrup if you are pregnant or breastfeeding unless prescribed. Coftos Syrup may cause dizziness, so drive only if you are alert. Coftos Syrup is not recommended for children below 6years. Avoid consuming alcohol along with Coftos Syrup as it could lead to increased dizziness. Keep your doctor informed about your health condition and the medicines you are taking to rule out any side effects/interactions.

Uses of Coftos Syrup

Treatment of Cough

Medicinal Benefits

Coftos Syrup is a combination of three drugs, namely: Ammonium chloride, Chlorpheniramine maleate, and Sodium citrate. Coftos Syrup is used to provide relief from cough. Ammonium chloride is an expectorant that helps loosen the congestion in the chest and throat by decreasing airway secretion's stickiness. Chlorpheniramine maleate is an antihistamine that works by blocking a chemical substance called histamine, which is responsible for causing allergic reactions. Sodium citrate is a mucolytic that loosens and thins the phlegm, making it easier to cough out. Together, Coftos Syrup provides relief from cough.

Directions for Use

Shake the bottle well before each use. Take the prescribed dose/quantity by mouth using the measuring cup/dosing syringe provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Coftos Syrup

  • Headache
  • Dizziness
  • Nausea
  • Fatigue
  • Dry mouth
  • Weakness
  • Restlessness

Drug Warnings

Do not take Coftos Syrup if you are allergic to any of its contents, if you are taking monoamine oxidase inhibitors (MAOI) or have taken them in the last 14days, or if you have pre-existing hyperchloremia (electrolyte imbalance). Inform your doctor before taking Coftos Syrup if you have asthma, prostate problems, glaucoma, bronchitis, glucose-galactose malabsorption, sucrase-isomaltase deficiency, fructose intolerance, cardiac insufficiency, pulmonary oedema, severe kidney or liver problems, or if you are taking hypnotics and anxiolytics. Consult your doctor if you are pregnant or breastfeeding. Coftos Syrup may cause dizziness and drowsiness, so drive only if you are alert. Coftos Syrup is not recommended for children below 6years. Avoid consuming alcohol along with Coftos Syrup as it could lead to increased dizziness.

Drug Interactions

Drug-Drug Interaction: Coftos Syrup may have interaction with anti-convulsant (phenytoin), antihistamine (diphenhydramine, cetirizine), anti-depressant (duloxetine), anti-anxiety (alprazolam), monoamine oxidase inhibitors (MAOI), and hypnotics/anxiolytics.

Drug-Food Interaction: Avoid consumption of alcohol while taking Coftos Syrup as it might cause increased dizziness and drowsiness. 

Drug-Disease Interaction: Coftos Syrup may have interactions with conditions such as asthma, prostate problems, glaucoma, glucose-galactose malabsorption, sucrase-isomaltase deficiency, fructose intolerance, and severe kidney or liver problems.

Drug-Drug Interactions Checker List

  • PHENYTOIN
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • DULOXETINE
  • ALPRAZOLAM

Habit Forming

No

Diet & Lifestyle Advise

  • Gargle with salt water for relief from sore throat.
  • Avoid smoking and consumption of alcohol.
  • Avoid dairy products such as milk as they may increase mucus production. Also, avoid processed or refined foods.
  • Replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts, and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid dry throat while you have a cough. It also helps loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Disease/Condition Glossary

Cough: Coughing is a body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Cough can be dry or productive. A productive cough (wet cough) develops sputum (phlegm or mucus) from the lungs, whereas a dry cough does not produce sputum. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing out thick, solid white mucus, it indicates that you may have a bacterial infection in the airways. Clear or light-coloured mucus indicates allergies or minor infection in the respiratory tract, and a yellow or green mucus indicates a respiratory infection. 

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Coftos Syrup as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Coftos Syrup may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Coftos Syrup should be used with caution in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Coftos Syrup should be used with caution in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Coftos Syrup is not recommended for children below 6years of age.

Country of origin

India

Manufacturer/Marketer address

Sector 1, Parwanoo, Himachal Pradesh 173220
Other Info - CO77947

Author Details

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FAQs

Coftos Syrup is used to provide relief from cough. Coughing (dry or productive) is a body's way of clearing irritants (like allergens, mucus, or smoke) from airways thereby preventing respiratory infection.
Coftos Syrup is a combination of three drugs, namely: Ammonium chloride, Chlorpheniramine maleate, and Sodium citrate. Ammonium chloride helps in loosening the congestion in the chest and throat by decreasing the stickiness of airway secretions. Chlorpheniramine maleate works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. Sodium citrate loosens and thins the phlegm, making it easier to cough out. Together, Coftos Syrup provides relief from cough.
Do not stop taking Coftos Syrup on your own as it may worsen cough or cause recurring symptoms. Therefore, take Coftos Syrup for as long as your doctor has prescribed it. If you experience any difficulty while taking Coftos Syrup, please consult your doctor.
Coftos Syrup contains Chlorpheniramine maleate, an antihistamine that helps in treating an allergy. It helps in providing relief from a runny nose, watery eyes, sneezing and sore throat.
Coftos Syrup should not be taken for longer durations unless prescribed by the doctor. If your condition does not improve despite taking Coftos Syrup for a week, consult your doctor, he/she may prescribe an alternate medicine.
Coftos Syrup contains chlorpheniramine maleate, an antihistamine. Therefore, do not take any other antihistamine-containing products such as cold and cough medicines along with Coftos Syrup.

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