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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Cofstop-CDX Syrup is used to treat dry cough. It contains Chlorpheniramine and Dextromethorphan, which work by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Also, it blocks the action of histamine, a substance responsible for causing allergic reactions. Thus, it helps relieve overall cough, cold and allergic symptoms. Some people may experience side effects such as dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness or excitation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Apex Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Cofstop-CDX Syrup

Cofstop-CDX Syrup is used to treat dry cough. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely. Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways. 

Cofstop-CDX Syrup is a combination of two drugs: Chlorpheniramine (antihistamine) and Dextromethorphan (cough suppressant). Chlorpheniramine belongs to the class of antihistamines or anti-allergic that work by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. On the other hand, Dextromethorphan belongs to the class of cough suppressants that work by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, Cofstop-CDX Syrup helps relieve overall cough, cold and allergic symptoms. 

Take Cofstop-CDX Syrup with or without food as advised by your doctor with the help of a measuring cup. Your doctor will recommend how often you take Cofstop-CDX Syrup based on your medical condition. Some people may experience dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness or excitation. Most of these side effects of Cofstop-CDX Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Cofstop-CDX Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Cofstop-CDX Syrup . Cofstop-CDX Syrup is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Cofstop-CDX Syrup . Avoid using Cofstop-CDX Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Drink plenty of fluids while taking Cofstop-CDX Syrup to loosen mucus. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Cofstop-CDX Syrup .

Uses of Cofstop-CDX Syrup

Treatment of Cough due to common cold.

Directions for Use

Shake the bottle well before use. Check the label for directions and take Cofstop-CDX Syrup with or without food in doses as prescribed by your doctor with the help of a measuring cup that is provided with the pack.

Medicinal Benefits

Cofstop-CDX Syrup is a combination of two drugs: Chlorpheniramine and Dextromethorphan, primarily used to treat dry cough. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling and congestion or stiffness. Dextromethorphan belongs to the class of cough suppressants that work by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, it decreases the need to cough.

How Cofstop-CDX Syrup Works

Cofstop-CDX Syrup is a combination of two drugs: Chlorpheniramine (antihistamine) and Dextromethorphan (cough suppressant). Chlorpheniramine belongs to the class of antihistamines or anti-allergic that work by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. On the other hand, Dextromethorphan belongs to the class of cough suppressants that work by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, Cofstop-CDX Syrup helps relieve overall cough, cold and allergic symptoms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cofstop-CDX Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Constipation
  • Restlessness or excitation

What if I have taken an overdose of Cofstop-CDX Syrup

Do not take more than the prescribed dose of Cofstop-CDX Syrup as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Cofstop-CDX Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Cofstop-CDX Syrup . Cofstop-CDX Syrup is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Cofstop-CDX Syrup . Avoid using Cofstop-CDX Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Drink plenty of fluids while taking Cofstop-CDX Syrup to loosen mucus. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Cofstop-CDX Syrup .

Drug-Drug Interactions

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DextromethorphanSelegiline
Critical
DextromethorphanTranylcypromine
Critical

Drug-Drug Interactions

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DextromethorphanSelegiline
Critical
How does the drug interact with Cofstop-CDX Syrup 100 ml:
Co-administration of Cofstop-CDX Syrup 100 ml and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Cofstop-CDX Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanTranylcypromine
Critical
How does the drug interact with Cofstop-CDX Syrup 100 ml:
Taking Tranylcypromine with Cofstop-CDX Syrup 100 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Cofstop-CDX Syrup 100 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Cofstop-CDX Syrup 100 ml:
Co-administration of Isocarboxazid with Cofstop-CDX Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Cofstop-CDX Syrup 100 ml and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanPargyline
Critical
How does the drug interact with Cofstop-CDX Syrup 100 ml:
Co-administration of Pargyline and Cofstop-CDX Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Cofstop-CDX Syrup 100 ml and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanRasagiline
Critical
How does the drug interact with Cofstop-CDX Syrup 100 ml:
Taking Rasagiline with Cofstop-CDX Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Cofstop-CDX Syrup 100 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
DextromethorphanPhenelzine
Critical
How does the drug interact with Cofstop-CDX Syrup 100 ml:
Co-administration of Phenelzine and Cofstop-CDX Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Cofstop-CDX Syrup 100 ml can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanProcarbazine
Critical
How does the drug interact with Cofstop-CDX Syrup 100 ml:
Co-administration of Cofstop-CDX Syrup 100 ml and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Cofstop-CDX Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
ChlorpheniraminePotassium citrate
Critical
How does the drug interact with Cofstop-CDX Syrup 100 ml:
Taking Cofstop-CDX Syrup 100 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Cofstop-CDX Syrup 100 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ChlorpheniraminePotassium chloride
Critical
How does the drug interact with Cofstop-CDX Syrup 100 ml:
Taking Cofstop-CDX Syrup 100 ml and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Cofstop-CDX Syrup 100 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.
DextromethorphanTramadol
Severe
How does the drug interact with Cofstop-CDX Syrup 100 ml:
Co-administration of Cofstop-CDX Syrup 100 ml and Tramadol may increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although there is a possible interaction between Cofstop-CDX Syrup 100 ml and Tramadol, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as seizures (fits), changes in blood pressure, confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, tremor, incoordination, blurred vision, muscle spasm or stiffness, nausea, vomiting, stomach cramp, and diarrhea, contact a doctor immediately. Do not discontinue any medication without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.

  • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as it may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Habit Forming

No

Therapeutic Class

COUGH AND COLD PREPARATIONS

Cofstop-CDX Syrup Substitute

Substitutes safety advice
  • Tossex DMR Syrup 100 ml

    1.26per tablet
  • Ambrodil-D Syrup 100 ml

    by AYUR

    0.95per tablet
  • Tixylix DX Dry Cough Syrup 100 ml

    0.94per tablet
  • Soventus DX Syrup 100 ml

    0.97per tablet
  • Zerotuss-D Syrup 100 ml

    by AYUR

    0.80per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Cofstop-CDX Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Cofstop-CDX Syrup .

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Pregnancy

Caution

The safety of Cofstop-CDX Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Cofstop-CDX Syrup is excreted in human milk. Cofstop-CDX Syrup is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Caution

Cofstop-CDX Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Cofstop-CDX Syrup .

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Liver

Caution

Take Cofstop-CDX Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Safe if prescribed

If you have any concerns regarding the use of Cofstop-CDX Syrup in patients with Kidney problems, please consult a doctor.

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Children

Caution

Cofstop-CDX Syrup is not recommended for children below 6 years of age. However, please consult a doctor before using Cofstop-CDX Syrup in children.

FAQs

Cofstop-CDX Syrup is used to treat dry cough. It helps relieve overall cough, cold and allergic symptoms.
Cofstop-CDX Syrup contains Chlorpheniramine and Dextromethorphan. Chlorpheniramine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Dextromethorphan is a cough suppressant that works by blocking the transmission of nerve signals from cough centre in the brain to the muscles that produce cough. Thus, decreases the urge to cough.
No, you are not recommended to consume alcohol with Cofstop-CDX Syrup as it may increase drowsiness. However, please consult a doctor before consuming alcohol with Cofstop-CDX Syrup .
Cofstop-CDX Syrup may be used to provide relief from allergic symptoms such as sneezing, runny nose, throat irritation or watery eyes. Cofstop-CDX Syrup contains Chlorpheniramine, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
Yes, Cofstop-CDX Syrup may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Cofstop-CDX Syrup to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.
Yes, Cofstop-CDX Syrup may cause drowsiness or dizziness. It is not necessary for everyone taking Cofstop-CDX Syrup to experience this side effect. However, avoid driving if you feel drowsy or dizzy after taking Cofstop-CDX Syrup .
You are recommended to take Cofstop-CDX Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after 1 week of using Cofstop-CDX Syrup , please consult your doctor.
No, you are not recommended to stop taking Cofstop-CDX Syrup without consulting your doctor as it may worsen cough or cause recurring symptoms. Therefore, take Cofstop-CDX Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Cofstop-CDX Syrup , please consult your doctor.
Cofstop-CDX Syrup may cause side effects such as drowsiness, dizziness, constipation, blurred vision, restlessness, or dry mouth/throat/nose. If these side effects persist or worsen, please consult your doctor.
No, you are not recommended to use Cofstop-CDX Syrup if you are taking medicines for psychiatric illness. However, please consult your doctor before taking Cofstop-CDX Syrup with other medicines.
Cofstop-CDX Syrup begins to show its action approximately after 2 hours of taking it. However, it differs from person to person based on their physiological nature.
Cofstop-CDX Syrup contains Chlorpheniramine, which increases the pressure in the eye and thus reduces the effectiveness of glaucoma medications. Therefore, discuss with your doctor about your eye problem before using Cofstop-CDX Syrup .
There is limited information regarding this. Therefore, please consult your doctor before using Cofstop-CDX Syrup if you are breastfeeding.
No, taking Cofstop-CDX Syrup in more than the recommended dose will not make it more effective, rather it can increase side effects. If the symptoms are not relieved by the recommended doses, please consult your doctor.
If you forget to take a dose of Cofstop-CDX Syrup , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the risk of side effects.

Country of origin

India

Manufacturer/Marketer address

III Floor SIDCO Garment Complex, Guindy, Chennai 600 032, India
Other Info - COF0140

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