Cobex D Eye Drop is a combination of antibiotics and corticosteroids used to treat bacterial eye and ear infections. It is used to treat eye infections such as conjunctivitis (infection of the outer white membrane of the eyeball) and corneal ulcers (ulcer that occurs in the transplant membrane of the eye called the cornea). This infection is highly contagious in nature and can pass from one to another. Signs and symptoms include pink/red-toned eyes, gritty feeling in eyes, itchiness in areas of eyes, teary eyes, and thick discharge around eyes. 

Cobex D Eye Drop contains Tobramycin and Dexamethasone. Tobramycin is an aminoglycoside which inhibits the growth of bacteria by interfering with protein synthesis and leads to cell death. Dexamethasone is a corticosteroid medicine that reduces swelling and redness by preventing infection-fighting white blood cells (WBCs) 

Cobex D Eye Drop is an external preparation and should be administered as advised by your doctor. Cobex D Eye Drop should be taken in the dose and duration your doctor advises. You are advised to take Cobex D Eye Drop for as long as your doctor has prescribed it for you, depending on your medical condition. Cobex D Eye Drop can cause some common side effects (when eye drops are used), including redness, itching, swelling, burning sensation, tearing, and temporary blurred vision (with ointment use). Most of these side effects of Cobex D Eye Drop do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Long-term use of eye drops may cause a fungal eye infection. So, take this medicine for a duration prescribed by your doctor.

Cobex D Eye Drop should be avoided if you are allergic to it, other aminoglycoside antibiotics or other ingredients. Inform your doctor if you are on any topical nonsteroidal anti-inflammatory drugs (NSAIDs), as Cobex D Eye Drop combined with topical NSAIDs may cause your eye wound to heal more slowly. Avoid wearing contact lenses during the treatment of ocular infection or inflammation, as it can worsen the condition. Tell your doctor about all your current medications and medical history before using Cobex D Eye Drop. Inform your doctor if you have any vision problems after using this medication. Tell your doctor if you are pregnant or breastfeeding. Cobex D Eye Drop is not recommended for use in children below two years of age. 

Cobex D Eye Drop is a combination of two drugs: Tobramycin (antibiotics) and Dexamethasone (corticosteroids). Tobramycin works by inhibiting the growth of bacteria. Dexamethasone blocks the chemical messenger in the brain responsible for causing inflammation (redness, itching, and swelling). As a result, it lowers inflammation, which could worsen the condition. Cobex D Eye Drop is used to prevent and treat inflammation and prevent possible bacterial infection of the eye after cataract surgery in adults and children above two years of age. 

• Eye redness
• Burning sensation
• Eye pain
• Dry eyes

If you are allergic to Cobex D Eye Drop or any other medicines, please tell your doctor. Consult your doctor before taking Cobex D Eye Drop if you are pregnant or breastfeeding. Cobex D Eye Drop is not recommended for children unless prescribed by a doctor. Let your doctor know if you have had myasthenia gravis (muscle weakness) or Parkinson’s disease, antibiotics like tobramycin may worsen muscle weakness. You are advised to remove soft contact lenses before using Cobex D Eye Drop as it contains a preservative that may cause eye irritation and discolouration of soft contact lenses. You can reinsert contact lenses after 15 minutes of using Cobex D Eye Drop. Do not use the topical non-steroidal inflammatory drug while using Cobex D Eye Drop. Cobex D Eye Drop contains dexamethasone; if you use a topical non-steroidal inflammatory drug and dexamethasone together, it may delay the healing of your eye wound. If you have diabetes, please consult your doctor before using Cobex D Eye Drop. The risk of intraocular pressure (glaucoma) and cataract formation is increased in diabetic patients. Cobex D Eye Drop may cause temporary vision problems (blurred vision), so be cautious while driving and operating machinery. 

Drug-drug interactions: Cobex D Eye Drop may interact with other antibiotics (e.g., vancomycin, gentamicin, kanamycin, streptomycin, cephalothin), pain relievers (e.g., diclofenac, bromfenac) antiviral (e.g., ritonavir, cobicistat, boceprevir, amprenavir, atazanavir), antifungal (e.g., itraconazole, ketoconazole, miconazole, posaconazole, voriconazole), antidiabetics (e.g., metformin, canagliflozin, glimepiride, pioglitazone), smallpox vaccine.

Drug-food interactions: No food interactions found.

Drug-disease interactions: Cobex D Eye Drop should be used with caution in patients with a corneal transplant, diabetes, myasthenia gravis, and Parkinson's disease.

• VANCOMYCIN
• GENTAMICIN
• KANAMYCIN
• STREPTOMYCIN
• CEPHALOTHIN
• DICLOFENAC
• BROMFENAC
• RITONAVIR
• COBICISTAT
• BOCEPREVIR
• AMPRENAVIR
• ATAZANAVIR
• ITRACONAZOLE
• KETOCONAZOLE
• MICONAZOLE
• POSACONAZOLE
• VORICONAZOLE
• METFORMIN
• CANAGLIFLOZIN
• GLIMEPIRIDE
• PIOGLITAZONE
• SMALLPOX VACCINE

• Sleep for at least 6-8 hours to rejuvenate your eyes naturally.
• Wash your eyes with clean water at least 2-3 times a day
• Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
• Placing cooled tea bags on your eyes while they are closed can be a way to relax and unwind.

• Do not take Cobex D Eye Drop on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections.
• Use of Cobex D Eye Drop for prolonged may result in a new fungal eye infection (secondary infection). Do not use Cobex D Eye Drop for longer than prescribed.
• Cobex D Eye Drop should not be administered directly into the anterior chamber of the eye.  

Bacterial eye infection: Bacterial eye infection occurs when harmful bacteria invade any part of the eye, such as the eyeball, conjunctiva, or cornea. The common bacterial eye infections are conjunctivitis, keratitis, etc. Conjunctivitis (pink eye) is the inflammation or infection of the conjunctiva (white part of the eye) and the inner eyelid. It is a highly contagious infection that is spread by eye secretions. Symptoms include redness, itchiness, and discharge or crusting around the eye. Keratitis is the inflammation of the cornea that occurs due to frequent use of contact lenses, injury, diabetes, or surgery.