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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Clozex Plus Tablet is used to treat anxiety. Besides this, it is also used to treat high blood pressure, panic disorder, seizure disorder, fast heartbeat, and migraine. It contains two medicines, namely Clonazepam and Propranolol. It may cause common side effects, such as dry mouth, slow heart rate, depression, fatigue (overtiredness), nightmares, sleep disturbances, memory impairment, and confusion.
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Manufacturer/Marketer :

Arbour Biotec Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Clozex Plus Tablet

Clozex Plus Tablet is used to treat anxiety. Besides this, Clozex Plus Tablet is also used to treat high blood pressure, panic disorder, seizure disorder, fast heartbeat, and migraine. Anxiety is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Symptoms of anxiety include rapid breathing, increased heart rate, restlessness, trouble concentrating, and difficulty falling asleep.

Clozex Plus Tablet is a combination of two drugs: Clonazepam (benzodiazepine) and Propranolol (beta-blocker). Clonazepam works by increasing the action of a chemical messenger called GABA; this helps suppress the excessive and abnormal activity of the nerve cells in the brain. Propranolol blocks certain chemical messengers' action on the heart and blood vessels; this helps reduce heart rate and blood pressure.

You are advised to take Clozex Plus Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as dry mouth, slow heart rate, depression, fatigue, nightmares, sleep disturbances, memory impairment, and confusion. You are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Clozex Plus Tablet on your own as it might cause withdrawal symptoms. Consult your doctor if you are pregnant or breastfeeding. Clozex Plus Tablet may cause dizziness and sleepiness; do not drive or handle machinery unless you are alert. Avoid consumption of alcohol while taking Clozex Plus Tablet as it may cause increased dizziness. Clozex Plus Tablet is not recommended for children as safety and effectiveness were not established. Keep your doctor informed about all the medicines you are taking, including prescription, non-prescription medicines and herbal supplements.

Uses of Clozex Plus Tablet

Treatment of Anxiety

Directions for Use

Take Clozex Plus Tablet on an empty stomach. Swallow the medicine as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Clozex Plus Tablet is a combination of two drugs, namely: Clonazepam and Propranolol. Clozex Plus Tablet is used to treat anxiety. Clonazepam is a benzodiazepine that increases the action of a chemical messenger called GABA; this helps suppress the excessive and abnormal activity of the nerve cells in the brain. Propranolol is a beta-blocker that works by blocking certain chemical messengers' action on the heart and blood vessels; this helps reduce heart rate and blood pressure. 

How Clozex Plus Tablet Works

Clozex Plus Tablet is a combination of two drugs: Clonazepam (benzodiazepine) and Propranolol (beta-blocker). Clonazepam works by increasing the action of a chemical messenger called GABA; this helps suppress the excessive and abnormal activity of the nerve cells in the brain. Propranolol blocks certain chemical messengers' action on the heart and blood vessels; this helps reduce heart rate and blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clozex Plus Tablet

  • Dry mouth
  • Slow heart rate
  • Depression
  • Fatigue
  • Nightmares
  • Sleep disturbances
  • Memory impairment
  • Confusion

What if I have taken an overdose of Clozex Plus Tablet

Do not take more than the prescribed dose of Clozex Plus Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Clozex Plus Tablet if you are allergic to any of its contents; if you have breathing or lung problems, severe liver problems, and myasthenia gravis (muscle problems). Inform your doctor if you have depression, porphyria, kidney, or liver disorder or are elderly. Clozex Plus Tablet may be habit-forming, so inform your doctor if you have a history of drug addiction or abuse. Keep your doctor informed about all the medicines you are taking, including prescription, non-prescription medicines and herbal supplements. Please do not stop taking Clozex Plus Tablet on your own as it might cause withdrawal symptoms. Clozex Plus Tablet may cause dizziness and sleepiness; do not drive or handle machinery unless you are alert. Avoid consumption of alcohol while taking Clozex Plus Tablet as it may cause increased dizziness. Clozex Plus Tablet is not recommended for children as safety and effectiveness were not established. Talk to your doctor immediately if you experience suicidal thoughts such as killing or harming yourself.

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
ClonazepamMorphine
Severe

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
How does the drug interact with Clozex Plus Tablet 10's:
Taking Clozex Plus Tablet 10's with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Clozex Plus Tablet 10's and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamMorphine
Severe
How does the drug interact with Clozex Plus Tablet 10's:
Using Morphine together with Clozex Plus Tablet 10's can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Morphine with Clozex Plus Tablet 10's can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like shortness of breath, feeling tired, having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ClonazepamDezocine
Severe
How does the drug interact with Clozex Plus Tablet 10's:
Co-administration of Clozex Plus Tablet 10's with Dezocine may increase the risk or severity of respiratory distress.

How to manage the interaction:
Although there is a possible interaction between Clozex Plus Tablet 10's and Dezocine, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling tired, dizzy, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
ClonazepamRemifentanil
Severe
How does the drug interact with Clozex Plus Tablet 10's:
Co-administration of Remifentanil with Clozex Plus Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Clozex Plus Tablet 10's with Remifentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
ClonazepamDroperidol
Severe
How does the drug interact with Clozex Plus Tablet 10's:
Co-administration of Droperidol with Clozex Plus Tablet 10's may increase the severity of slow heart rate and low blood pressure, and using it with Clozex Plus Tablet 10's may increase the risks.

How to manage the interaction:
Although taking Clozex Plus Tablet 10's and Droperidol together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - heart beating too slowly, low blood pressure, an irregular heartbeat, sudden dizziness, feeling lightheaded, fainting, or your heartbeat feels strange - make sure to call a doctor right away." Do not stop using any medications without a doctor's advice.
ClonazepamTramadol
Severe
How does the drug interact with Clozex Plus Tablet 10's:
Co-administration of Clozex Plus Tablet 10's with Tramadol may significantly lead to adverse effects such as respiratory difficulties (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Clozex Plus Tablet 10's and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamButorphanol
Severe
How does the drug interact with Clozex Plus Tablet 10's:
Co-administration of Butorphanol with Clozex Plus Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Although taking Clozex Plus Tablet 10's and Butorphanol together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamPethidine
Severe
How does the drug interact with Clozex Plus Tablet 10's:
Combining Meperidine with Clozex Plus Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Pethidine with Clozex Plus Tablet 10's together can possibly result in an interaction, but it can be taken if your doctor has advised it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
ClonazepamPentazocine
Severe
How does the drug interact with Clozex Plus Tablet 10's:
Co-administration of Pentazocine with Clozex Plus Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Clozex Plus Tablet 10's with Pentazocine together can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamAlfentanil
Severe
How does the drug interact with Clozex Plus Tablet 10's:
Co-administration of Alfentanil with Clozex Plus Tablet 10's can increase the risk of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Clozex Plus Tablet 10's and Alfentanil, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Attend therapy sessions regularly.

  • Eat a healthy diet.

  • Try to stay active and exercise regularly.

  • Take ample rest. Get enough sleep.

  • Meditate regularly as it helps in easing the anxiety.

  • Avoid smoking, caffeine, and alcohol consumption.

  • Foods and drinks like salmon, chamomile, turmeric, dark chocolate, green tea, and yoghurt may help with anxiety.

Habit Forming

Yes

Therapeutic Class

ANXIOLYTICS

Clozex Plus Tablet Substitute

Substitutes safety advice
  • Clotas Plus Tablet 10's

    4.72per tablet
  • Dizeral CP Tablet 10's

    5.72per tablet
  • PROVANOL FORTE 0.5MG TABLET

    7.83per tablet
  • Epitril-Beta 0.5mg Tablet 10's

    by AYUR

    6.62per tablet
  • KLOCALM PLUS TABLET

    6.30per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol as it might affect the efficacy of Clozex Plus Tablet .

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Pregnancy

Unsafe

Clozex Plus Tablet is unsafe for use during pregnancy. Please consult your doctor before taking Clozex Plus Tablet if you are pregnant; your doctor will prescribe Clozex Plus Tablet if the benefits outweigh the risks in some life-threatening situations.

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Breast Feeding

Safe if prescribed

Limited data suggest that Clozex Plus Tablet does not have any significant risk for the baby. However, please consult your doctor before taking Clozex Plus Tablet ; your doctor will decide whether Clozex Plus Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Clozex Plus Tablet may cause dizziness and sleepiness. Do not drive or handle machinery unless you are alert.

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Liver

Caution

Clozex Plus Tablet should be used in caution in patients with liver problems. Dose adjustment may be needed. Please consult your doctor before taking Clozex Plus Tablet if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

It is probably safe to use Clozex Plus Tablet in patients with kidney problems. However, please consult your doctor before taking Clozex Plus Tablet if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Clozex Plus Tablet is not recommended for children as safety and effectiveness were not established.

FAQs

Clozex Plus Tablet is used to treat anxiety. Besides this, Clozex Plus Tablet is also used to treat high blood pressure, panic disorder, seizure disorder, fast heartbeat, and migraine.Â
Clozex Plus Tablet contains Clonazepam and Propranolol. Clonazepam works by increasing the action of a chemical messenger called GABA; this helps suppress the excessive and abnormal activity of the nerve cells in the brain. Propranolol blocks certain chemical messengers' action on the heart and blood vessels; this helps reduce heart rate and blood pressure.
Do not stop taking Clozex Plus Tablet on your own as it might increase the seizure frequency, chest pain and heart attack. Stopping it suddenly may cause withdrawal symptoms such as nausea, anxiety, muscle pain, and flu-like symptoms. Consult your doctor if you experience any difficulty while taking Clozex Plus Tablet ; the doctor may gradually reduce the dose.
Dry mouth could be a side-effect of Clozex Plus Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Clozex Plus Tablet has high habit-forming potential. Therefore, take Clozex Plus Tablet only in the dose and duration prescribed by the doctor.
Clozex Plus Tablet might cause weight gain or weight loss, depending on person to person. Eat a balanced diet and exercise regularly to prevent weight gain; if you experience weight loss, increase your diet portions.
Clozex Plus Tablet may cause postural hypotension. Postural hypotension is a sudden lowering in blood pressure leading to dizziness on standing. To prevent this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better.
Clozex Plus Tablet should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
Yes, Clozex Plus Tablet may cause dizziness and sleepiness. Avoid driving or operating machinery unless you are fully alert.
The side effects of Clozex Plus Tablet include slow heart rate, fatigue, dry mouth, depression, nightmares, sleep disturbances, memory impairment and confusion. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

B-213, Someshwar Complex-1, Popular Plaza,Satellite,Ahmedabad-380015
Other Info - CLO0721

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