Closet 10mg/250mg Tablet is used in the treatment of spasmodic pain and discomfort due to biliary colic, intestinal colic, renal colic and spasmodic dysmenorrhea (painful, irregular periods). It also helps alleviate the symptoms of irritable bowel syndrome (IBS). Colic is the intensive and uncontrollable crying in babies for a prolonged period for no certain reason. Dysmenorrhea (Abdominal cramps) is an unpleasant sensory and emotional experience associated with irregular periods. It occurs just before or during menses. Irritable bowel syndrome is an intestinal disorder that causes stomach pain, wind, constipation, and diarrhoea.

Closet 10mg/250mg Tablet is composed of two medicines: Dicyclomine (antispasmodic/anticholinergic agent) and Paracetamol (analgesic). Dicyclomine/Dicycloverine helps in blocking the activity of certain natural substances that are responsible for causing pain. Paracetamol has both analgesic (pain reducer) and antipyretic (fever reducer) properties, which also decrease inflammation.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Closet 10mg/250mg Tablet include experiencing dizziness, nausea (feeling sick), digestion problems like constipation, flatulence, diarrhoea, and skin reactions like rashes and hives. Most of the side effects of Closet 10mg/250mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are sensitive or allergic to Closet 10mg/250mg Tablet or any other medications. Before using Closet 10mg/250mg Tablet, let your doctor know if you have liver, kidney or heart diseases and any other medical history. Some antacids may inhibit the absorption of Closet 10mg/250mg Tablet, hence consult your doctor. Closet 10mg/250mg Tablet may cause dizziness; hence, do not drive or operate machinery until you feel better. Pregnant and breastfeeding women should consult their doctor before using Closet 10mg/250mg Tablet. Closet 10mg/250mg Tablet should be used in children only when recommended by a doctor.

Closet 10mg/250mg Tablet is composed of two medicines: Dicyclomine (antispasmodic) and Paracetamol (mild analgesic and fever reducer). Closet 10mg/250mg Tablet helps relieve spasmodic pain and discomfort due to biliary colic, intestinal colic, renal colic, and spasmodic dysmenorrhea (painful irregular menses/periods). Dicyclomine helps in blocking the activity of certain natural substances in the body responsible for causing pain. On the other hand, Paracetamol has analgesic (pain reducer) and antipyretic (fever reducer) properties, decreasing inflammation. Together, they effectively reduce pain and inflammation in conditions of intestine inflammation, spasms and painful menstruation.

• Dizziness

• Nausea (feeling sick)

• Constipation

• Flatulence

• Diarrhoea

• Rashes/hives

Let your doctor know if you are sensitive to Closet 10mg/250mg Tablet or its components. Closet 10mg/250mg Tablet should be used with caution and only under a doctor’s supervision if you have stomach/intestinal problems and diarrhoea due to intestine surgeries like ileostomy and colostomy. Pregnant and breastfeeding women should use Closet 10mg/250mg Tablet with proper consultation and caution. Closet 10mg/250mg Tablet may cause blurry vision and dizziness affecting your mental focus, hence do not drive or operate machinery until you feel better. Drinking alcohol may worsen the side effects; therefore, it is advised to avoid the alcohol intake while using Closet 10mg/250mg Tablet. Closet 10mg/250mg Tablet should be used in children only when prescribed by the doctor.

Drug-Drug Interaction: Closet 10mg/250mg Tablet may interact with cholesterol-lowering drugs (cholestyramine), vomiting medicines (domperidone), anti-HIV drugs (zidovudine), blood thinners (warfarin), corticosteroids, blood pressure-lowering medicines, drugs to lower organ rejection (tacrolimus), anti-cancer or anti-arthritis drugs (methotrexate), urinary alkalinizer (potassium citrate), and potassium supplements.

Drug-Food Interaction: Intake of alcohol should be avoided while taking Closet 10mg/250mg Tablet.

Drug-Disease Interaction: Patients affected with liver disease, bleeding disorder, urinary tract infection (UTI), myasthenia gravis, high blood pressure, and alcoholism should seek medical advice before starting Closet 10mg/250mg Tablet.

• CHOLESTYRAMINE
• DOMPERIDONE
• ZIDOVUDINE
• WARFARIN
• TACROLIMUS
• METHOTREXATE
• POTASSIUM CITRATE

• Avoid or limit the intake of alcohol and caffeine.

• Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

• Limit taking high fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 

• Do not have large meals at a time, instead try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.

• Practice yoga and recreation techniques to manage your emotional stress.

• If you are lactose intolerant, avoid using dairy products since it can worsen your IBS.

• If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.

• Drink plenty of fluids and dress lightly to prevent heatstroke and dehydration.

• Avoid overly sweating activities like hard exercises and using hot tubs.

Colic: Colic is the intensive and uncontrollable crying in babies for a prolonged period for no certain reason. Colicky babies usually have distended bellies, release gas, raise their legs to the chest, and bend or arch their backs.

Irritable Bowel Syndrome (IBS): It is also termed as IBS colitis, mucous colitis, spastic colon, nervous colon, and spastic bowel. It is an inflammatory bowel disease that affects the large intestine. Symptoms of an IBS include abdominal pain, bloating, diarrhoea, mucus in stools, wind, constipation, tiredness, anxiety, depression, heartburn, indigestion, and headaches.

Dysmenorrhea refers to abdominal cramps/pain and an unpleasant sensory/emotional experience associated with irregular periods. It occurs just before or during menses.