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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cloff Xl 125mg/5ml Suspension is used to treat a wide range of bacterial infections. It contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for bacterial cell growth. As a result, bacterial cells are not able to reproduce and grow. Thus, it helps prevent infections. Common side effects of Cloff Xl 125mg/5ml Suspension are feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping.

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Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Cloff Xl 125mg/5ml Suspension

Cloff Xl 125mg/5ml Suspension belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Antibiotics inhibit the growth of microorganisms and are given to treat bacterial infections.

Cloff Xl 125mg/5ml Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff Xl 125mg/5ml Suspension helps in the prevention of infections.

Like all medicines, Cloff Xl 125mg/5ml Suspension may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping. Most of these side effects do not require medical attention and gradually resolve over time. However, if you notice any of these side effects persist or worsen your child’s condition, inform your doctor immediately.

Inform your doctor about your child's entire medical history. Other drugs or supplements should not be combined with Cloff Xl 125mg/5ml Suspension unless prescribed by a doctor. Even if your child is feeling better, do not miss any dose and complete the entire course of medication. Stopping the medication too soon may cause the infection to recur or worsen.

Uses of Cloff Xl 125mg/5ml Suspension

Treatment of Bacterial infections

Directions for Use

Oral Suspension: Administer the prescribed dose to the child using the measuring cup/dosing syringe/dropper. Shake the bottle well before use.

Medicinal Benefits

Cloff Xl 125mg/5ml Suspension belongs to the macrolide class of antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori).

How Cloff Xl 125mg/5ml Suspension Works

Cloff Xl 125mg/5ml Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff Xl 125mg/5ml Suspension helps in the prevention of infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cloff Xl 125mg/5ml Suspension

  • Headache
  • Diarrhoea
  • Being sick (vomiting)
  • Nausea (feeling sick)
  • Loss of appetite
  • Taste change
  • Bloating
  • Indigestion
  • Abdominal pain
  • Insomnia (difficulty sleeping)

What if I have taken an overdose of Cloff Xl 125mg/5ml Suspension

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Cloff Xl 125mg/5ml Suspension may include severe stomach pain, nausea, vomiting, and diarrhea. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Before using Cloff Xl 125mg/5ml Suspension, let your doctor know about all your children's medical conditions, sensitivities, and all medications used. Do not use any other drugs or supplements with Cloff Xl 125mg/5ml Suspension unless prescribed by the doctor. Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Cloff Xl 125mg/5ml Suspension in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Cloff Xl 125mg/5ml Suspension and iron supplements and antacids.

Drug-Drug Interactions

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ClarithromycinDroperidol
Critical
ClarithromycinLomitapide
Critical

Drug-Drug Interactions

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ClarithromycinDroperidol
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
Co-administration of Droperidol with Cloff Xl 125mg/5ml Suspension 60ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Cloff Xl 125mg/5ml Suspension 60ml with Droperidol can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinLomitapide
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
When Lomitapide is taken with Cloff Xl 125mg/5ml Suspension 60ml, it can lower the metabolism of Lomitapide.

How to manage the interaction:
Co-administration of Cloff Xl 125mg/5ml Suspension 60ml and Lomitapide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, and liver damage, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinLovastatin
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
Taking Cloff Xl 125mg/5ml Suspension 60ml with Lovastatin can increase the risk of muscle problems.

How to manage the interaction:
Co-administration of Cloff Xl 125mg/5ml Suspension 60ml and Lovastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinDihydroergotamine
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
When Dihydroergotamine is taken with Cloff Xl 125mg/5ml Suspension 60ml, the amount of Dihydroergotamine in the blood can go up.

How to manage the interaction:
Taking Cloff Xl 125mg/5ml Suspension 60ml with Dihydroergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinVenetoclax
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
When Venetoclax is taken with Cloff Xl 125mg/5ml Suspension 60ml, the body's ability to break down Venetoclax may be reduced.

How to manage the interaction:
Taking Cloff Xl 125mg/5ml Suspension 60ml with Venetoclax is not recommended, please consult your doctor before taking it.
ClarithromycinRegorafenib
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
When Regorafenib is taken with Cloff Xl 125mg/5ml Suspension 60ml, may alter the blood levels and effects of Regorafenib.

How to manage the interaction:
Co-administration of Cloff Xl 125mg/5ml Suspension 60ml and Regorafenib can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
ClarithromycinBepridil
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
Co-administration of Bepridil with Cloff Xl 125mg/5ml Suspension 60ml may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Cloff Xl 125mg/5ml Suspension 60ml with Bepridil is not recommended as it can result in an interaction, it should be taken only if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinMesoridazine
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
Co-administration of Cloff Xl 125mg/5ml Suspension 60ml and Mesoridazine may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Cloff Xl 125mg/5ml Suspension 60ml and Mesoridazine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinTerfenadine
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
When Terfenadine is taken with Cloff Xl 125mg/5ml Suspension 60ml, the amount of Terfenadine in the blood can go up.

How to manage the interaction:
Co-administration of Cloff Xl 125mg/5ml Suspension 60ml and Terfenadine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinAlprazolam
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
The combination of Alprazolam and Cloff Xl 125mg/5ml Suspension 60ml may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Alprazolam and Cloff Xl 125mg/5ml Suspension 60ml, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to give probiotics after taking the full course of Cloff Xl 125mg/5ml Suspension to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • The BRAT diet (bananas, rice, apple sauce, toast) can help with diarrhoea from antibiotics.
  • Give plenty of water to the child. Staying hydrated is important, especially when you’re child sick.
  • Eating a broad range of plant-based foods such as vegetables, fruits, nuts, seeds, pulses and wholegrains helps to build a healthy gut microbiome.
  • Avoid feeding too many calcium-enriched foods and drinks because they may interfere with the functioning of Cloff Xl 125mg/5ml Suspension.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Cloff Xl 125mg/5ml Suspension Substitute

Substitutes safety advice
  • Crixan 125 Suspension 30 ml

    4.64per tablet
  • Synclar 125 mg Banana Flavour Dry Syrup 30 ml

    4.64per tablet
  • Claribid Granules 30 ml

    4.64per tablet
  • Clarinova Dry Syrup 30 ml

    4.53per tablet
  • Bioclar Dry Syrup 30 ml

    4.64per tablet
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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Caution

Inform your doctor if your child has liver problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor if your child has kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Cloff Xl 125mg/5ml Suspension can be given safely to children. Give this medicine to your child in the doses prescribed by the paediatrician.

FAQs

Cloff Xl 125mg/5ml Suspension is used to treat Bacterial infections.
Cloff Xl 125mg/5ml Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff Xl 125mg/5ml Suspension helps in the prevention of infections.
After taking antibiotics such as Cloff Xl 125mg/5ml Suspension, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.
Cloff Xl 125mg/5ml Suspension treats only bacterial infections. It will not work for viral infections such as the common cold, or flu.
No, Cloff Xl 125mg/5ml Suspension is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with a doctor's advice only.
Side effects are rare with Cloff Xl 125mg/5ml Suspension and do not usually last long. They will get better after a day or two. If those side effects persist, reach out to the doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,INDIA
Other Info - CLO1242

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