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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Clavam XR Tablet is used to treat bacterial infections, including ear, sinus, respiratory tract, urinary tract, skin, soft tissue, dental, joint and bone infections. It works by killing the infection-causing bacteria. In some cases, this medicine may cause side effects such as vomiting, nausea, and diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Alkem Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Clavam XR Tablet

Clavam XR Tablet is used to treat bacterial infections in the body that affect the skin, soft tissues, lungs, ears, urinary tract, and nasal sinuses. It should be mentioned that viral infections like the flu and the common cold are not treated by this medication.

Clavam XR Tablet consists of two medicines: Amoxycillin and Clavulanic acid. Amoxycillin acts by destroying the outer protein layer, thereby killing the bacteria (bactericidal action). Clavulanic acid inhibits the enzyme beta-lactamase, which prevents bacteria from destroying the efficacy of amoxycillin. As a result, the action of Clavulanic acid allows Amoxycillin to work better and kill the bacteria. Clavam XR Tablet does not work against infections caused by viruses, including colds and flu.

The dose of Clavam XR Tablet can vary depending on your condition and the severity of the infection. Also, it is recommended to complete the course of medicine even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance). The common side effects of Clavam XR Tablet include vomiting, nausea, and diarrhoea. Everyone may not experience the above side effects. In case of any discomfort, speak with a doctor.

Before starting Clavam XR Tablet , please inform your doctor if you have any allergy (against any antibiotic) or kidney or liver problems. Do not take Clavam XR Tablet on your own as self-medication since it may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Clavam XR Tablet is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.

Uses of Clavam XR Tablet

Treatment of Bacterial Infections (Ear infections (acute otitis media), Bronchitis, Pneumonia, Urinary tract infections, skin infections, etc.)

Medicinal Benefits

Clavam XR Tablet is a broad-spectrum antibiotic that covers a very wide range of bacterial infections. Clavam XR Tablet has Clavulanic acid, which protects amoxycillin from getting destroyed by the bacterial enzyme, thus increasing its efficacy. Besides this, it helps overcome antibiotic resistance in bacteria that is caused by the enzyme beta-lactamase. This makes the drug effective in multiple infections like ear infections (acute otitis media), bronchitis, pneumonia, urinary tract infections, skin infections, etc.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clavam XR Tablet

  • Vomiting
  • Diarrhea
  • Indigestion

Drug Warnings

After taking Clavam XR Tablet , if you have an allergy-like symptom, including rash, swelling of the face/lips/throat, difficulty breathing, or tight chest tightness, immediately contact your doctor. Do not take Clavam XR Tablet if you have an allergy to Clavam XR Tablet , penicillin or cephalosporin class of antibiotics. People with liver diseases or jaundice (yellowing of skin/eye) should not take Clavam XR Tablet , as it can severely affect the liver. Consult your doctor before taking Clavam XR Tablet if you are pregnant or breastfeeding. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.

Drug Interactions

Drug-Drug Interaction: Caution should be exercised when Clavam XR Tablet is administered in combination with gout medicine (allopurinol, probenecid), blood thinners (warfarin), anticancer, or anti-arthritis drug (methotrexate), and drug to prevent organ transplant (mycophenolate mofetil).

Drug-Food Interaction: Avoid taking eating high-fat meals as this may make it harder for your body to absorb Clavam XR Tablet .

Drug-Disease Interaction: People affected with liver disease (like jaundice), glandular fever (viral infection with fever and sore throat), or colitis (bowel disease that affects the large intestine, causing irritation, inflammation, and ulcers in the colon) should not take Clavam XR Tablet .

Drug-Drug Interactions Checker List

  • ALLOPURINOL
  • PROBENECID
  • WARFARIN
  • METHOTREXATE
  • MYCOPHENOLATE MOFETIL

Habit Forming

No

Diet & Lifestyle Advise

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics.

  • Whole grains like whole-grain bread and brown rice should be included in your diet.

  • Probiotics should be taken after taking a full course of Clavam XR Tablet in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea.

  • Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.

  • Avoid alcoholic beverages with Clavam XR Tablet as they can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Clavam XR Tablet in fighting off infections.

Special Advise

  • Even if you feel better after taking Clavam XR Tablet , do not stop taking it until your doctor says so. This might cause the symptoms to reappear and make the infection difficult to treat due to antibiotic resistance.

  • Make sure you drink plenty of fluids when you are sick. This will, in general, help you clear out the infection faster, protect you from dehydration, and help you overcome some unpleasant side effects of taking Clavam XR Tablet .

  • Some people may be allergic to Clavam XR Tablet or other penicillin or cephalosporin group of antibiotics. So a prior sensitivity test may be necessary. Inform your doctor if you are allergic to any medicine, particularly antibiotics belonging to these groups.

Disease/Condition Glossary

Bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any part of the body and multiply very quickly. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. You can experience generalised symptoms like fevers, chills, and fatigue when you get infected with bacteria. A few harmful bacteria commonly cause infections are Streptococcus, Staphylococcus, and E. coli. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections. 

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Alcohol

Caution

Avoid consumption of alcohol during the treatment with Clavam XR Tablet as it may worsen the side effects like dizziness.

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Pregnancy

Consult your doctor

If you are pregnant, consult your doctor before taking Clavam XR Tablet . Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

This medication passes into breast milk. If you are a nursing mother, consult your doctor before taking Clavam XR Tablet . Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Clavam XR Tablet may cause dizziness in some people, so it may affect your ability to drive. Avoid driving or operating machines until you are alert after taking Clavam XR Tablet .

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Liver

Caution

Clavam XR Tablet to be taken with caution if you have a history of liver conditions. Your doctor may adjust the dose if necessary based on your condition.

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Kidney

Caution

Clavam XR Tablet to be taken with caution, especially if you have a history of kidney conditions. Your doctor may adjust the dose if necessary based on your condition.

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Children

Consult your doctor

Please consult the doctor. Your child's doctor will decide the dosage of this medicine depending on the weight and the severity of the infection.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - CLA0072

Author Details

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FAQs

Clavam XR Tablet is used to prevent middle ear and sinus infections, throat or lung respiratory tract infections, urinary tract infections, skin infections, soft tissue infections, dental infections, and joint and bone infections.
Clavam XR Tablet contains Amoxycillin and Clavulanic acid. Amoxycillin works by preventing the formation of bacterial cell covering, which is necessary for the survival of the bacteria. Thus it kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of amoxycillin against the bacteria. Together, Clavam XR Tablet helps in treating bacterial infections.
Clavam XR Tablet is known to cause stomach upset, indigestion, nausea, and diarrhea. To avoid these side effects, please take Clavam XR Tablet with a meal. Also, Clavam XR Tablet should be taken at evenly spaced intervals to avoid any unpleasant side effects and for best results.
Generally, the penicillin group of antibiotics is not advised to be taken with methotrexate, which is used for conditions like psoriasis, rheumatoid arthritis, etc. They may cause unpleasant side effects when taken together. However, Clavam XR Tablet is relatively safer to take with methotrexate, but only if prescribed by the doctor. It is best to discuss with your doctor about using the two medicines together, who may weigh the pros and cons and decide what is best for you.
Usually, Clavam XR Tablet does not cause jaundice. But sometimes, it can cause jaundice in elderly people who have been taking the medication for a prolonged time. Please consult your doctor immediately if you notice any yellowing of the skin/eyes.
Clavam XR Tablet does not treat a viral infection like the flu or a common cold. It is best to consult the doctor to know if you need Clavam XR Tablet for your condition.
Yes, after taking Clavam XR Tablet , you may have diarrhea. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration). Do not take anti-diarrhea medicine on your own; consult your doctor if the condition worsens.
Clavam XR Tablet is not known to reduce the efficacy of birth control pills and emergency contraceptive pills. However, if you develop diarrhea or vomiting due to Clavam XR Tablet , you are recommended to use other contraceptive methods such as condoms along with contraceptives to avoid unwanted pregnancies. Discuss with your doctor if you have any concerns regarding using Clavam XR Tablet and your birth control pills.
Clavam XR Tablet may show its effect 1.5 hours after taking the medicine. However, clinical improvement may be noticed after 48 hours.
Clavam XR Tablet should be taken for the duration prescribed by the doctor based on your condition. Usually, it is taken every 8-12 hours.
Clavam XR Tablet contains amoxicillin and clavulanic acid used to treat bacterial infections of the ear, sinus, respiratory tract, urinary tract, skin, soft tissue, dental, joints and bones.
Yes, Clavam XR Tablet is safe to use if prescribed by the doctor.
Clavam XR Tablet should not be used if you are allergic to any of its components or if you had jaundice or liver problems when taking an antibiotic.
Do not exceed the recommended dose of Clavam XR Tablet as it might cause stomach upset or convulsions. Take Clavam XR Tablet only as advised by the doctor.
Store Clavam XR Tablet at room temperature (below 25°C). Keep it out of sight and reach of children. To help protect the environment, avoid throwing away any medicines via wastewater or household waste. Ask your pharmacist regarding the disposal of medicines.
To treat your infection effectively, continue taking Clavam XR Tablet for the prescribed duration even if your symptoms are relieved.
Clavam XR Tablet may cause an allergic reaction like skin rash, vasculitis (inflammation of blood vessels), angioedema (swelling), and difficulty breathing. Consult the doctor if you experience these symptoms.
No, Clavam XR Tablet does not cause drowsiness. Sometimes, it might cause dizziness as an uncommon side effect. Drive or operate machinery only if you are alert.
Clavam XR Tablet should be swallowed as a whole with water. Take the medicine with a meal.
If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking Clavam XR Tablet .
The common side effects of Clavam XR Tablet include vomiting, nausea, and diarrhoea. In case of any discomfort, speak with a doctor.
Clavam XR Tablet should be taken only if prescribed by the doctor. It should not be taken by people who are allergic to amoxicillin, clavulanic acid, penicillin or any of the other ingredients of this medicine, ever had a severe allergic reaction (skin rash or swelling of the face or throat) to any other antibiotic or liver problems/jaundice (yellowing of the skin) when taking an antibiotic.
Let the doctor know if you are taking gout medicine (allopurinol, probenecid), blood thinners (warfarin), anticancer, or anti-arthritis drugs (methotrexate), and drugs to prevent organ transplant (mycophenolate mofetil).
Seek immediate medical attention if you have overdosed on Clavam XR Tablet . Taking too much of Clavam XR Tablet may cause upset stomach (nausea, vomiting or diarrhoea) or convulsions.

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