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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Ciplar Plus 5 Tablet is used to treat migraine. It contains Propranolol and Flunarizine which improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. It effectively treats and reduces the severity and frequency of migraine headaches. Also, it is also used to treat vertigo (spinning sensation). It may cause common side effects such as dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Ciplar Plus 5 Tablet

Ciplar Plus 5 Tablet is used to treat migraine. Migraine is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Its symptoms include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.

Ciplar Plus 5 Tablet consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits the cortical spreading of depression and electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine. It is also used to treat vertigo (spinning sensation).

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Ciplar Plus 5 Tablet include dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting Ciplar Plus 5 Tablet . Ciplar Plus 5 Tablet may cause weight gain in some cases, so avoid eating junk and eat a healthy, balanced diet, including home-cooked food. Consult your doctor before taking Ciplar Plus 5 Tablet if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol along with Ciplar Plus 5 Tablet as it could lead to increased drowsiness.

Uses of Ciplar Plus 5 Tablet

Treatment of Migraine.

Directions for Use

Swallow Ciplar Plus 5 Tablet as a whole with a glass of water; do not chew, crush or break it.

Medicinal Benefits

Ciplar Plus 5 Tablet is used to treat migraine. It consists of 'Propranolol' and 'Flunarizine'. Propranolol is a beta-blocker and has anxiolytic (anxiety-reducing), anti-arrhythmic, and antihypertensive properties. It works by lowering cerebral (brain) blood flow and inhibits cortical spreading depression, as well as electrical activity in the brain that causes pain and inflammation. It reduces the severity and frequency of migraine headaches. Flunarizine is a channel blocker that improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine. 

How Ciplar Plus 5 Tablet Works

Ciplar Plus 5 Tablet consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits the cortical spreading of depression and electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ciplar Plus 5 Tablet

  • Weight gain
  • Slow heart rate
  • Tiredness
  • Depression
  • Drowsiness
  • Abnormal dreams
  • Cold extremities (hands and feet)

What if I have taken an overdose of Ciplar Plus 5 Tablet

Do not take more than the prescribed dose of Ciplar Plus 5 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor if you have any history of liver or kidney diseases, breathing problems (asthma, bronchitis, emphysema), diabetes, heart failure, heart rhythm problems (sinus bradycardia, Wolff-Parkinson-White syndrome, atrioventricular block), overactive thyroid, blood circulation problems (Raynaud's disease), adrenal gland tumour (pheochromocytoma), depression, metabolic acidosis (excess acid in the blood), and myasthenia gravis (muscle weakness) before starting Ciplar Plus 5 Tablet . Please consult your doctor if you are pregnant and planning to conceive if the doctor advised you Ciplar Plus 5 Tablet . Avoid consuming alcohol along with Ciplar Plus 5 Tablet as it could lead to increased dizziness and drowsiness.

Drug-Drug Interactions

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PropranololThioridazine
Critical
PropranololIndacaterol
Severe

Drug-Drug Interactions

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PropranololThioridazine
Critical
How does the drug interact with Ciplar Plus 5 Tablet 10's:
Coadministration of thioridazine with Ciplar Plus 5 Tablet 10's may increase the blood levels of thioridazine and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Ciplar Plus 5 Tablet 10's and thioridazine, they can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, and shortness of breath contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololIndacaterol
Severe
How does the drug interact with Ciplar Plus 5 Tablet 10's:
Using Ciplar Plus 5 Tablet 10's together with indacaterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Ciplar Plus 5 Tablet 10's can cause breathing problems.

How to manage the interaction:
Although taking Ciplar Plus 5 Tablet 10's together with Indacaterol can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololDisopyramide
Severe
How does the drug interact with Ciplar Plus 5 Tablet 10's:
Taking Ciplar Plus 5 Tablet 10's and disopyramide together can enhance the effects of disopyramide.

How to manage the interaction:
Although there may be an interaction, disopyramide can be taken with Ciplar Plus 5 Tablet 10's if prescribed by your doctor. However, consult your doctor if you experience dizziness, fainting, palpitations, or slow or fast heart rate, consult your doctor immediately. Do not stop using any medications without consulting your doctor.
PropranololTheophylline
Severe
How does the drug interact with Ciplar Plus 5 Tablet 10's:
Using Ciplar Plus 5 Tablet 10's together with Theophylline makes the Ciplar Plus 5 Tablet 10's less effective in controlling blood pressure, and it also increases the effects of theophylline

How to manage the interaction:
Although taking Ciplar Plus 5 Tablet 10's together with Theophylline can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience nausea, vomiting, sleeplessness, tremors, restlessness, irregular heartbeats, or difficulty breathing. Do not stop using any medication without consulting a doctor.
PropranololVerapamil
Severe
How does the drug interact with Ciplar Plus 5 Tablet 10's:
Using Ciplar Plus 5 Tablet 10's and verapamil together may lead to increased side effects.

How to manage the interaction:
Although taking Ciplar Plus 5 Tablet 10's together with Verapamil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not stop taking any medication without consulting a doctor.
PropranololSalmeterol
Severe
How does the drug interact with Ciplar Plus 5 Tablet 10's:
Using Ciplar Plus 5 Tablet 10's together with salmeterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Ciplar Plus 5 Tablet 10's can sometimes cause breathing problems.

How to manage the interaction:
Although taking Ciplar Plus 5 Tablet 10's together with Salmeterol can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololLabetalol
Severe
How does the drug interact with Ciplar Plus 5 Tablet 10's:
Taking Ciplar Plus 5 Tablet 10's with Labetalol can potentially enhance the effects of orthostatic hypotension (low blood pressure that happens when standing after sitting or lying down).

How to manage the interaction:
Although taking Ciplar Plus 5 Tablet 10's together with Labetalol can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience lightheadedness or dizziness upon standing, blurred vision, weakness, fainting, or confusion. Do not discontinue any medicine without consulting a doctor.
PropranololIsoetarine
Severe
How does the drug interact with Ciplar Plus 5 Tablet 10's:
Using Ciplar Plus 5 Tablet 10's together with isoetharine may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Ciplar Plus 5 Tablet 10's can sometimes cause breathing problems.

How to manage the interaction:
Although taking Ciplar Plus 5 Tablet 10's together with Isoetarine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololRivastigmine
Severe
How does the drug interact with Ciplar Plus 5 Tablet 10's:
Coadministration of rivastigmine with Ciplar Plus 5 Tablet 10's can cause an abnormally slow heart rate and low blood pressure.

How to manage the interaction:
Although taking Ciplar Plus 5 Tablet 10's together with Rivastigmine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience lightheadedness, dizziness, fainting, or irregular heartbeat. Do not discontinue any medicine without consulting a doctor.
PropranololAminophylline
Severe
How does the drug interact with Ciplar Plus 5 Tablet 10's:
Coadministration of Aminophylline with Ciplar Plus 5 Tablet 10's together can make Ciplar Plus 5 Tablet 10's less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Ciplar Plus 5 Tablet 10's can cause an interaction. However, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. Instead, eat a healthy diet and do regular exercise to avoid weight gain caused due to Ciplar Plus 5 Tablet .
  • Avoid loud music, extreme temperatures, bright lights, and noisy places as it can increase headache.
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine to relieve headaches.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS

Ciplar Plus 5 Tablet Substitute

Substitutes safety advice
  • Betacap Plus 5 Capsule 10's

    10.80per tablet
  • Zinepra 5 Tablet 10's

    by AYUR

    9.09per tablet
  • Provanol Plus 5 Tablet 10's

    12.06per tablet
  • Inderal F 5 Tablet 10's

    by AYUR

    7.92per tablet
  • Flupanol 5 mg Tablet 10's

    9.00per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Ciplar Plus 5 Tablet . Alcohol intake, along with Ciplar Plus 5 Tablet , may cause increased dizziness and drowsiness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning to conceive before using Ciplar Plus 5 Tablet .

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Breast Feeding

Caution

Please consult your doctor before taking Ciplar Plus 5 Tablet if you are a lactating mother.

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Driving

Caution

Ciplar Plus 5 Tablet may make you feel drowsy. Do not drive or operate machinery if you experience drowsiness.

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Liver

Caution

Therapy with propranolol should be administered cautiously in patients with liver disease. Please consult your doctor if you have a history of liver impairment/liver disease.

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Kidney

Caution

Plasma clearance of Propranolol in Ciplar Plus 5 Tablet is reduced in patients with renal failure. Please consult your doctor if you have a history of kidney impairment/kidney disease.

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Children

Safe if prescribed

Ciplar Plus 5 Tablet is safe to use for children below 12 years of age when prescribed by the doctor.

FAQs

Ciplar Plus 5 Tablet belongs to the class of anti-migraine drugs used to treat migraine.
Ciplar Plus 5 Tablet is a combination of two drugs: Propranolol and Flunarizine. Ciplar Plus 5 Tablet treats migraine by reducing the blood flow to the brain, and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation.
Ciplar Plus 5 Tablet may sometimes cause weight gain during its prolonged use. It is always advised to maintain a well-balanced, healthy diet and exercise regularly.
Ciplar Plus 5 Tablet does not work for a sudden migraine attack. It is helpful in only preventing new episodes of migraine headaches. Please let your doctor know if you have sudden attacks to be prescribed other suitable medications.
Ciplar Plus 5 Tablet is contraindicated in asthma, slow heart rate, abnormal heart rhythms, heart conditions like AV (Atrioventricular) block or sick sinus syndrome, depression, and Parkinson's disease. Please consult your doctor before starting Ciplar Plus 5 Tablet if you have a medical history.
Your doctor will prescribe Ciplar Plus 5 Tablet to prevent any new episodes of migraine. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of migraine. Ciplar Plus 5 Tablet also contains Propranolol, and its sudden withdrawal may cause sweating, shaking, irregular heartbeat, and worsening of underlying angina or heart attack. Hence, do not stop using Ciplar Plus 5 Tablet unless advised by your doctor.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - CIP0466

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