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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 22, 2024 | 7:36 PM IST
Cinatreat Tablet is used to treat primary hyperparathyroidism, secondary hyperparathyroidism, and parathyroid cancer. It contains Cinacalcet which works by signalling the body to produce a less parathyroid hormone. In some cases, this medicine may cause side effects such as vomiting, nausea, rash, headache, muscle pain, and diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition

CINACALCET-30MG

Manufacturer/Marketer

Genix Lifescience Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Cinatreat Tablet

Cinatreat Tablet is used to treat primary hyperparathyroidism, secondary hyperparathyroidism, and parathyroid-carcinoma. Primary hyperparathyroidism is a condition in which one or more parathyroid glands make too much parathyroid hormone (PTH). Secondary hyperparathyroidism is the medical condition of excessive secretion of parathyroid hormone (PTH) by the parathyroid glands in response to hypocalcemia (low blood calcium levels), with resultant hyperplasia (increase in the number of cells) of these glands. Parathyroid cancer is a rare disease in which malignant (cancer) cells form in a parathyroid gland's tissues.

Cinatreat Tablet contains 'cinacalcet', which works by signalling the body to produce a less parathyroid hormone to decrease the amount of calcium in the blood.

In some cases, Cinatreat Tablet may cause common side effects like vomiting, nausea, rash, headache, muscle pain, and diarrhoea. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult a doctor.

Do not take Cinatreat Tablet if you are allergic to ‘cinacalcet’ or other ingredients. Inform your doctor if you are taking any other medicines other than Cinatreat Tablet . Before taking Cinatreat Tablet , inform your doctor if you have chronic kidney disease, gastrointestinal bleeding, heart failure, liver diseases, or cardiac arrhythmia. Cinatreat Tablet is not recommended in hypotension and hypocalcemia. Consult your doctor if you are pregnant or breastfeeding.

Uses of Cinatreat Tablet

Treatment of Primary hyperparathyroidism, secondary hyperparathyroidism, and Parathyroid cancer.

Medicinal Benefits

Cinatreat Tablet contains 'cinacalcet', which belongs to the class of medications called 'calcimimetics' used in the treatment of primary hyperparathyroidism, secondary hyperparathyroidism, and parathyroid-carcinoma. It works by signalling the body to produce a less parathyroid hormone to decrease the amount of calcium in the blood.

Directions for Use

Swallow the medicine as a whole with a glass of water. Do not chew, crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cinatreat Tablet

  • Fever or chills

  • Vomiting

  • Nausea

  • Rash

  • Blurred vision

  • Chest pain

  • Headache

  • Lower back or side pain

  • Nervousness

  • Difficult or painful urination

  • Diarrhoea

Drug Warnings

Do not take Cinatreat Tablet if you are allergic to any of its ingredients. Inform your doctor if you are taking medicines other than Cinatreat Tablet . Before taking Cinatreat Tablet , inform your doctor if you have chronic kidney disease, gastrointestinal bleeding, heart failure, liver diseases, adynamic bone disease, or cardiac arrhythmia. Consult your doctor if you are pregnant or breastfeeding. Before taking Cinatreat Tablet , inform your doctor if you have rare hereditary problems of galactose intolerance.

Drug Interactions

Drug-Drug Interactions: Cinatreat Tablet may interact with antifungal drugs (ketoconazole and itraconazole), antacids (Balofloxacin), anti-depressant  (amitryptiline, amoxapine, pimozide, thioridazine, fluvoxamine, imipramine), a protease inhibitor (indinavir, ritonavir), antibiotics (clarithromycin, erythromycin), hormonal drugs (tamoxifen), antiarrhythmics (flecainide, carvedilol, verapamil),  anti-cancer (vinblastine), anti-TB (rifampicin).

Drug-Food Interactions: Do not take grapefruit or grapefruit juice while using Cinatreat Tablet .

Drug-Disease Interactions: Cinatreat Tablet should be used with caution in patients with chronic kidney disease, gastrointestinal bleeding, heart failure, liver diseases, adynamic bone disease, cardiac arrhythmia, hypotension, hypocalcemia, or galactose intolerance.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • BALOFLOXACIN
  • AMITRIPTYLINE
  • AMOXAPINE
  • PIMOZIDE
  • THIORIDAZINE
  • FLUVOXAMINE
  • IMIPRAMINE
  • INDINAVIR
  • RITONAVIR
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • TAMOXIFEN
  • FLECAINIDE
  • CARVEDILOL
  • VERAMAPIL
  • VINBLASTINE
  • RIFAMPICIN

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid refined foods, such as white bread, pasta, and sugar.

  • Use healthy cooking oils, such as olive oil or coconut oil.

  • Drink plenty of fluids.

  • Exercise regularly. 

  • Don't smoke.

Special Advise

  • Monitor your calcium levels regularly during treatment with Cinatreat Tablet . Inform your doctor if you notice signs of low calcium levels, such as numbness or tingling around the mouth or muscle aches.

Disease/Condition Glossary

Hyperparathyroidism: Hyperparathyroidism is a condition in which one or more of your parathyroid glands become overactive and release (secrete) too much parathyroid hormone (PTH). This causes the levels of calcium in your blood to rise, a condition known as hypercalcemia. There are two types of hyperparathyroidism: primary and secondary.

Primary hyperparathyroidism: Primary hyperparathyroidism is a condition in which one or more parathyroid glands make too much parathyroid hormone (PTH). This can lead to the loss of bone tissue. Symptoms include constipation, frequent urination, increased thirst, joint pain, kidney pain (due to kidney stones), loss of appetite, and muscle weakness.

Secondary hyperparathyroidism: Secondary hyperparathyroidism is the medical condition of excessive secretion of parathyroid hormone (PTH) by the parathyroid glands in response to hypocalcemia (low blood calcium levels), with resultant hyperplasia (increase in the number of cells) of these glands. This disorder is primarily seen in patients with chronic kidney failure. Symptoms include muscle pain and weakness.

Parathyroid cancer: Parathyroid cancer is a rare disease in which malignant (cancer) cells form in a parathyroid gland's tissues. Symptoms include weakness, tiredness, nausea, vomiting, loss of appetite, weight loss for no known reason, being much more thirsty than usual, urinating much more than usual, and constipation.

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Alcohol

Caution

Cinatreat Tablet with alcohol may cause unpleasant effects. So please consult your doctor before taking Cinatreat Tablet with alcohol.

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Pregnancy

Caution

Cinatreat Tablet is not recommended for use in pregnant women unless necessary. Before taking this medicine, the risks and benefits should be discussed with the doctor.

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Breast Feeding

Caution

Cinatreat Tablet is not recommended for use in breastfeeding women unless necessary. Before taking this medicine, the risks and benefits should be discussed with the doctor. Your doctor may advise you to discontinue the medicine or breastfeeding based on your clinical condition.

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Driving

Caution

Cinatreat Tablet may cause blurred vision, dizziness, and drowsiness in some patients. You are advised not to perform any activities, such as driving a vehicle or operating machinery, if you experience any of these symptoms during treatment with this medicine.

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Liver

Caution

Cinatreat Tablet should be used with caution in patients with liver disease. A dose adjustment of Cinatreat Tablet may be needed in some cases. So, Please consult your doctor.

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Kidney

Caution

Cinatreat Tablet is not recommended for use in patients suffering from chronic kidney disease who are not being treated with dialysis due to the increased risk of hypocalcemia (low blood calcium levels). Depending on your clinical condition, dose adjustments or replacement with a suitable alternative drug should be considered.

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Children

Caution

Cinatreat Tablet should not be used in children below 12 years of age unless prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - CIN0286

Author Details

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FAQs

Cinatreat Tablet is used to treat primary hyperparathyroidism, secondary hyperparathyroidism, and parathyroid-carcinoma.
Cinatreat Tablet works by signalling the body to produce a less parathyroid hormone to decrease the amount of calcium in the blood.
Cinatreat Tablet is not recommended for use in patients suffering from chronic kidney disease who are not being treated with dialysis due to the increased risk of hypocalcemia (low blood calcium levels). Replacement with a suitable alternative should be considered based on the clinical condition.
If you have hypotension (low blood pressure) and hypocalcemia (low calcium levels in the blood), please contact a doctor before taking Cinatreat Tablet .
Cinatreat Tablet should be used with extreme caution in patients suffering from seizures due to the increased risk of worsening their condition. Please consult your doctor before taking Cinatreat Tablet .
Take Cinatreat Tablet as prescribed by the doctor. Cinatreat Tablet should be taken with food or shortly after a meal. To help you remember to take Cinatreat Tablet , take it at around the same time daily.
Cinatreat Tablet may cause diarrhoea. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the diarrhoea persists or worsens.
Sometimes lactose is used in medicines. Inform the doctor if you have sugar/lactose intolerance. Check the label to know if Cinatreat Tablet contains lactose.
Cinatreat Tablet may cause common side effects like vomiting, nausea, rash, headache, muscle pain, and diarrhoea. If the side effects persist or worsen, consult a doctor.

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