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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST

Cerviprime 0.5 mg Gel 3 gm is used to prepare the cervix for the initiation of labour in pregnant women. It contains Dinoprostone, which stimulates uterine muscles and increases the contractions of the uterus. This medicine may sometimes cause side effects such as back pain, vomiting, diarrhoea, flushing of the skin, and foetal distress. Inform the doctor if you are taking any other medication, or have any pre-existing medical conditions.

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Prescription drug

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Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

VAGINAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Cerviprime 0.5 mg Gel 3 gm

Cerviprime 0.5 mg Gel 3 gm belongs to the class of medication called 'oxytocic' or 'uterotonic', primarily used for the initiation or improvement of uterine contraction (antepartum) and producing uterine contraction during the third stage of labour (postpartum). Labour induction stimulates uterine (womb) contractions during pregnancy before labour pain begins to achieve a vaginal birth. It is recommended by the doctor for labour induction for various reasons, especially when there is a concern for a mother's health or a baby's health.

Cerviprime 0.5 mg Gel 3 gm contains a prostaglandin Dinoprostone that stimulates uterine muscles and increases the uterus' contractions. It works by increasing the production of a natural substance called prostaglandins (PGs) that softens and widens the cervix (opening of the womb) so that the baby comes out easily. Also, it increases uterus contractions and hence induces labour. As a result, these increased uterine contractions help deliver the child.

Cerviprime 0.5 mg Gel 3 gm is not intended for self-application as it is typically used in hospital settings under the supervision of medical healthcare professionals. After taking the medication, you may be asked to lie down for at least 30 minutes. You may experience certain common side effects such as back pain, vomiting, diarrhoea, flushing of the skin, and fetal distress in some cases. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not use Cerviprime 0.5 mg Gel 3 gm if you are allergic to Cerviprime 0.5 mg Gel 3 gm or its ingredients. Be sure your doctor knows your entire pregnancy history, especially if you have ever had a C-section or major surgery on your uterus, if you have had a baby born in a breech position, or if you have had a difficult labour or delivery of a previous child. Also, mention all the other medications you are taking that affect how Cerviprime 0.5 mg Gel 3 gm works. A Cerviprime 0.5 mg Gel 3 gm should not be used for a prolonged time if the contractions do not increase or have severe pre-eclamptic toxaemia (high blood pressure, protein in the urine, and swelling) or blood or heart circulation problems. A professional should always administer Cerviprime 0.5 mg Gel 3 gm at a hospital and not practice self-administration.

Uses of Cerviprime 0.5 mg Gel 3 gm

Management of Labour induction

Medicinal Benefits

Cerviprime 0.5 mg Gel 3 gm contains a prostaglandin 'Dinoprostone' primarily used in inducing labour. It plays a major role in childbirth as it softens and widens the cervix (opening of the womb) so that the baby comes out easily. Also, it increases prostaglandin production, which further increases uterus contractions and hence induces labour. As a result, these increased uterine contractions help deliver the child.

Directions for Use

Cerviprime 0.5 mg Gel 3 gm is not intended for self-application as it is typically used in hospital settings under the supervision of medical healthcare professionals. After taking the medication, you may be asked to lie down for at least 30 minutes. If you are given a suppository form, it will be removed just before labour.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cerviprime 0.5 mg Gel 3 gm

  • Vomiting
  • Diarrhoea
  • Back pain
  • Fetal distress
  • Flushing of the skin

Drug Warnings

Do not take Cerviprime 0.5 mg Gel 3 gm if you are allergic to Cerviprime 0.5 mg Gel 3 gm or its ingredients. Be sure your doctor knows your entire pregnancy history, especially if you have ever had a C-section or major surgery on your uterus, if you have had a baby born in a breech position, or if you have had a difficult labour or delivery of a previous child. Increasing the dose of Cerviprime 0.5 mg Gel 3 gm can be harmful if your womb already has too strong contractions, any obstructions in the pathway that might prevent the delivery or if the baby is not receiving a sufficient oxygen supply. Also, the use of Cerviprime 0.5 mg Gel 3 gm is not advisable if the baby is wrongly positioned in the birth canal, the baby’s head is too large to fit through the pelvis, the placenta lies near the neck of the womb, the placenta separates from the womb before birth, the womb is over-extended and likely to tear (in case you are carrying more than one baby). A Cerviprime 0.5 mg Gel 3 gm should not be used for a prolonged time if the contractions do not increase or have severe pre-eclamptic toxaemia (high blood pressure, protein in the urine, and swelling) or blood or heart circulation problems. A professional should always administer Cerviprime 0.5 mg Gel 3 gm at a hospital and not practice self-administration.

Drug Interactions

Drug-Drug Interaction: Cerviprime 0.5 mg Gel 3 gm is known to interact with other oxytocic medicines (oxytocin, methylergonovine, ergonovine, carbetocin).

Drug-Food Interaction: Cerviprime 0.5 mg Gel 3 gm is known to interact with alcohol. So, do not consume alcohol while using Cerviprime 0.5 mg Gel 3 gm.

Drug-Disease Interaction: Cerviprime 0.5 mg Gel 3 gm should not be given to the patients with previous cesarean section, heart, lung, kidney or liver disease, glaucoma (increased pressure in the eye), epilepsy, genital herpes, suffered from asthma, hypertension (high blood pressure), if you are more than 40 weeks pregnant or are more than 35 years, the pelvis is too small for normal delivery.

Drug-Drug Interactions Checker List

  • OXYTOCIN
  • METHYLERGONOVINE
  • ERGONOVINE
  • MISOPROSTOL

Habit Forming

No

Diet & Lifestyle Advise

  • Long walks can help relieve stress, keep your body strong, and help with easy delivery.
  • Please take a little bit of Castrol oil. It stimulates prostaglandin, which ripens the cervix and initiates labour.
  • For some foods like dates, raspberry tea leaves are known to ripen the cervix and get labour started.
  • Acupressure also stimulates labour and helps in delivery.

Special Advise

  • Your and baby's heart rate should be constantly monitored while using Cerviprime 0.5 mg Gel 3 gm to avoid any complications.
  • Cerviprime 0.5 mg Gel 3 gm is given for induction of labour or stimulation of labour; it must be given under medical supervision in a hospital. The doctor will advise lying down for 30 minutes after using Cerviprime 0.5 mg Gel 3 gm.
  • If you have genital herpes infection, do not use Cerviprime 0.5 mg Gel 3 gm.

Disease/Condition Glossary

Labour induction: When artificial oxytocin is induced to stimulate the uterus to contract, it is known as labour induction. There are various reasons for labour induction, like miscarriage if pregnancy lasts longer than 42 weeks, a cesarean section or if your water breaks out. Induction of labour is planned in advance, and your doctor will discuss all the advantages and disadvantages with you priorly.

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Alcohol

Unsafe

No interactions were established.

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Pregnancy

Safe if prescribed

Cerviprime 0.5 mg Gel 3 gm is used to induce uterine contractions at delivery time. It is not for self-application purposes as usually applied in hospital settings under the supervision of medical healthcare professionals.

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Breast Feeding

Caution

Cerviprime 0.5 mg Gel 3 gm is most likely unsafe to use while breastfeeding. Based on limited human data, the drug may pass into breast milk and harm your infant.

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Driving

Unsafe

No interactions were established.

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Liver

Caution

Inform your doctor if you have liver problems before taking Cerviprime 0.5 mg Gel 3 gm. Your doctor will weigh the benefits and the risks before prescribing this medicine.

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Kidney

Caution

Cerviprime 0.5 mg Gel 3 gm can cause fluid retention if used in patients with kidney disease. Hence, inform your doctor if you have kidney problems before taking Cerviprime 0.5 mg Gel 3 gm. Your doctor will weigh the benefits and the risks before prescribing this medicine.

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Children

Unsafe

Cerviprime 0.5 mg Gel 3 gm is not recommended for children below the age of 18 years. The safety and effectiveness of Cerviprime 0.5 mg Gel 3 gm have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

Country of origin

INDIA

Manufacturer/Marketer address

Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Other Info - CER0004

Author Details

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FAQs

Cerviprime 0.5 mg Gel 3 gm is used for the initiation or improvement of uterine contraction (antepartum) and producing uterine contraction during the third stage of labour (postpartum).
Cerviprime 0.5 mg Gel 3 gm contains a prostaglandin Dinoprostene that works by increasing the production of a natural substance called prostaglandins (PGs), which softens and widens the cervix (opening of the womb) and increases uterus contractions. As a result, these increased uterine contractions and widened cervix help deliver the child.
Cerviprime 0.5 mg Gel 3 gm is given as a suppository or a gel applied at a hospital only under strict medical supervision. The dose to be administered will be decided by your doctor, depending on your current medical situation.
The most common side effects of Cerviprime 0.5 mg Gel 3 gm include vomiting, back pain, diarrhoea, flushing of the skin, and fetal distress. You might also feel increased uterine contractions for some time, but these are manageable under medical supervision.
If you have a previous premature delivery or a c-section, or cervical surgery, please inform your doctor before starting Cerviprime 0.5 mg Gel 3 gm. Also, mention a detailed medical history to your doctor to avoid complications.
No, Cerviprime 0.5 mg Gel 3 gm should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects like fetal distress or delivery complications.
It is advised to use Cerviprime 0.5 mg Gel 3 gm only if prescribed by a doctor as there are chances of increased complications in women aged 35 and above and if you smoke.

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