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Written By Thota sri Harshini ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 23, 2025 | 12:20 PM IST

Cefrine Syrup is used to treat bacterial infections in children. It contains Cefdinir, which interferes with bacterial cell wall formation and kills the bacteria. In some cases, this medicine may cause side effects such as diarrhea, nausea, stomach pain, vomiting, rash, and abnormal stools. Before giving this medicine to your child, inform the doctor if the child is taking any other medications or has any pre-existing medical conditions.

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Composition :

CEFDINIR-125MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Cefrine Syrup

Cefrine Syrup belongs to a class of medications called antibiotics. It is used to treat bacterial infections of the urinary tract, bones and joints, heart, lungs, brain, chest, ears, skin, and soft tissues. Bacteria infection occurs when harmful bacteria grow in the body and multiply quickly. It can infect any part of the body. It does not work against infections caused by viruses such as flu or the common cold.

Cefrine Syrup contains Cefdinir, a cephalosporin antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. This damages the bacterial cell wall and kills bacteria.

Cefrine Syrup to be given as prescribed by your doctor. Use it for as long as your doctor has prescribed it for your child based on their medical condition. In some cases, your child may experience diarrhea, nausea, stomach pain, vomiting, rash, and abnormal stools. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if your child is allergic to Cefrine Syrup, cephalosporin antibiotics or any other medicines. You are advised to maintain a time gap of a minimum of 2 hours if you are giving this medicine to your child with other medicines like antacids containing aluminium, magnesium, iron supplements, and multivitamins containing iron. It is not recommended for infants under 6 months of age as the safety and efficacy were not established.

Uses of Cefrine Syrup

Cefrine Syrup is used to treat bacterial infections in children.

Medicinal Benefits

Cefrine Syrup contains Cefdinir, a cephalosporin antibiotic used to treat several bacterial infections. Cefdinir is a broad-spectrum antibiotic that acts against aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It interferes with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thus, it damages the bacterial cell wall and kills bacteria.

Side Effects of Cefrine Syrup

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Vomiting
  • Abnormal stools
  • Rash

Directions for Use

Cefrine Syrup is administered orally by measuring the prescribed dose using the measuring cup. Shake well before each use to mix the contents properly.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Please tell your doctor if the child is allergic to Cefrine Syrup, penicillins, cephalosporin antibiotics, or any of its ingredients. If your child has diabetes, kidney or liver problems, a weak immune system or inflammation of the large intestine, inform your doctor before giving this medicine. It is not recommended for babies below six months of age, as the safety and effectiveness were not established.  You are recommended to complete the entire course of Cefrine Syrup as your doctor prescribes for effective results. Cefrine Syrup may interact with specific tests such as glucose (sugar) in urine and Coomb’s test, giving false-positive results. Therefore, please inform your doctor that the child takes it before undergoing any tests. You are advised to maintain a time gap of a minimum of 2 hours between giving Cefrine Syrup and antacids containing aluminium, magnesium, iron supplements and multivitamins containing iron. These may reduce the body's absorption of this medicine.

Therapeutic Class

ANTIBIOTICS

Drug-Drug Interactions

verifiedApollotooltip
CefdinirBCG vaccine
Critical
CefdinirArgatroban
Severe

Drug-Food Interactions

verifiedApollotooltip
CEFDINIR-125MGVitamin B complex foods, Vitamin B12 rich foods
Moderate

Diet & Lifestyle Advise

  • After completing the entire course of Cefrine Syrup, give probiotics under the doctor's guidance to restore any healthy bacteria that may have been killed in the intestines. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea.
  • Giving certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi to a child can restore the good bacteria in the intestine.
  • Fibre-rich foods can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your child's diet.
  • Make sure the child drinks plenty of water or other fluids every day while you are taking Cefrine Syrup.

Habit Forming

No

How Cefrine Syrup Works

Cefrine Syrup contains Cefdinir, a cephalosporin antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. This damages the bacterial cell wall and kills bacteria.

What if I have taken an overdose of Cefrine Syrup

Never give more than the prescribed dose. An overdose of Cefrine Syrup causes nausea, vomiting, stomach pain, diarrhoea, or seizures. Seek immediate medical attention if it happens accidentally and if you experience any unusual symptoms.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

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Liver

Caution

Give Cefrine Syrup with caution under doctor guidance, especially if the child has a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Give Cefrine Syrup with caution as advised by the doctor, especially if the child has a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Safe if prescribed

Cefrine Syrup should not be used in infants less than 6 months of age as the safety and efficacy were not established.

Country of origin

India

Manufacturer/Marketer address

409, Antriksh Bhawan, 22 Kasturba Gandhi Marg, New Delhi - 110 001.
Other Info - CEF0061

Author Details

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Cefrine Syrup Substitute

Substitutes safety advice
  • Adcef Suspension 30 ml

    6.66per tablet
  • Sefdin Syrup 30 ml

    2.81per tablet
  • Zinir Dry Syrup 30 ml

    2.07per tablet
  • SEFDIN DS SUSPENSION 30ML

    3.33per tablet
  • CEFDIEL 125MG SUSPENSION 30ML

    0.90per tablet

FAQs

Cefrine Syrup is used to treat bacterial infections of the urinary tract, blood, bones and joints, heart, lungs, brain, chest, ears, skin or soft tissues.
Cefrine Syrup works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. This damages the bacterial cell wall and kills bacteria.
Cefrine Syrup may cause diarrhoea in some children as a common side effect. However, if the condition persists, worsens, or notices blood or mucus in stools, avoid giving it and consult a doctor immediately.
Cefrine Syrup may interfere with the urine test (for sugar) and blood test giving false-positive results. Therefore, if your child is about to undergo any laboratory tests, inform your doctor or lab technician that the child is taking Cefrine Syrup.
Cefrine Syrup is not used to treat viral infections. It is an antibiotic that is used to treat only bacterial infections.
Cefrine Syrup is not recommended for babies below six months of age as the safety and effectiveness are not established.
Do not exceed the recommended dose of Cefrine Syrup of your child, as it may lead to severe side effects. If you think your child has taken too much, consult your doctor immediately. Always follow the prescribed dosage and administration instructions carefully to keep your child safe.
If your child is on insulin therapy you are recommended to consult your doctor before giving Cefrine Syrup to your child as it may change glucose levels in the blood. Always follow the doctor's instructions.
Do not give other medications along with Cefrine Syrup unless prescribed by your doctor. This medicine may interact with other medications such as lower high uric acid levels (probenecid), steroids (dexamethasone, methylprednisolone, prednisone), blood thinner (warfarin), immune suppressants (tacrolimus, ciclosporin), cholera vaccine, and typhoid vaccine.
If your child is on iron therapy, you should consult your doctor before giving Cefrine Syrup to your child, as iron may reduce the absorption of this medicine, making it less effective.
Antibiotics usually do not interfere with the components in vaccines or cause a bad reaction in a child who has just been vaccinated. However, it’s best to consult your doctor before going to treatment with Cefrine Syrup if your child is vaccinated.
The doctor may order regular kidney and liver tests to monitor your child's health and ensure their organs are working properly while taking Cefrine Syrup or having a specific medical condition.
Yellow or green mucus from a child's nose can indicate that their body is fighting off an infection, as it may contain white blood cells and other debris. However, it's always best to consult with your paediatrician for guidance and proper evaluation.
It is unknown. However, if your child has stomach pain, cramps, or very loose, watery, or bloody stools consult your doctor immediately.
The common side effects of Cefrine Syrup may include diarrhoea, nausea, vomiting, stomach pain, abnormal stools, and rash in some cases. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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