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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:19 PM IST

Cedroin 90mg Injection is used in the treatment of Hypercalcemia in Malignancy, Paget's disease, and Osteolytic bone metastases of breast cancer. It contains Pamidronate as an active ingredient, which belongs to the class of bisphosphonates. It works by inhibiting the osteoclast bone resorption, which causes bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. Thus, it helps retain the normal density of bones and restores bone integrity, bone strength and bone health.

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Synonym

PAMIDRONATE DISODIUM

Composition

PAMIDRONATE-90MG

Manufacturer/Marketer

Health Biotech Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Cedroin 90mg Injection

Cedroin 90mg Injection is a hypocalcemic agent that belongs to the bisphosphonates class. It is mainly used in lowering blood calcium levels and bone metastases/lesions in cancer patients. Besides this, it is also used to treat mild to moderate Paget's disease. Hypercalcemia (increased calcium levels) is a condition in which the calcium level in your blood is elevated due to certain conditions. Paget’s disease is a serious condition of bone that disrupts the replacement of old bone tissue with new bone tissue, resulting in the new bone that is abnormally shaped, weak, and brittle.

Cedroin 90mg Injection contains Pamidronate as an active ingredient, which belongs to the class of bisphosphonates. It works by inhibiting the osteoclast bone resorption, which causes bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. Thus, it helps retain the normal density of bones and restores bone integrity, bone strength and bone health.

Cedroin 90mg Injection may cause certain side effects such as injection site reactions, stomach pain, loss of appetite, nausea, vomiting, fever, headache, dizziness, mouth sores, constipation, and cough. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist for a longer period, please consult your doctor. Cedroin 90mg Injection is a parenteral preparation. A trained healthcare professional will administer it. Hence, do not self-administer.

Cedroin 90mg Injection should be avoided if you are allergic to it or any other components present in it. Before receiving Cedroin 90mg Injection, let your doctor know about all your medical conditions, sensitivities, and medications you are using to rule out any interactions. Cedroin 90mg Injection should be used under caution if you have/had kidney disease, liver problems, bone disorders, musculoskeletal pain, and high blood pressure. Cedroin 90mg Injection is not recommended for use in pregnant women due to foetal harm, and whether this medicine can be used for breastfeeding mothers is unknown. Hence, inform your doctor if you are pregnant or are breastfeeding before receiving Cedroin 90mg Injection. This medicine is not recommended for use in children as safety and efficacy have not been established.

Uses of Cedroin 90mg Injection

Treatment of Hypercalcemia in Malignancy, Paget's disease, and Osteolytic bone metastases of breast cancer

Medicinal Benefits

Cedroin 90mg Injection contains Pamidronate as an active ingredient, which belongs to the class of bisphosphonates. It works by inhibiting the osteoclast bone resorption, which causes bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. Thus, it helps retain the normal density of bones and restores bone integrity, strength, and health.

Directions for Use

Cedroin 90mg Injection will be administrated by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cedroin 90mg Injection

  • Injection site reactions
  • Nausea
  • Vomiting
  • Dizziness
  • Constipation
  • Stomach pain
  • Loss of appetite
  • Headache
  • Cough
  • Fever
  • Mouth sores

Drug Warnings

Cedroin 90mg Injection should be avoided if you are allergic to it or any other components present in it. Before receiving Cedroin 90mg Injection, let your doctor know about all your medical conditions, sensitivities, and medication history you are using to rule out any interactions. Cedroin 90mg Injection should be used under caution if you have/had kidney disease, liver problems, bone disorders, musculoskeletal pain, and high blood pressure. Cedroin 90mg Injection is not recommended for use in pregnant women due to foetal harm, and whether this medicine can be used for breastfeeding mothers is unknown. Hence, inform your doctor if you are pregnant or are breastfeeding before receiving Cedroin 90mg Injection. This medicine is not recommended for use in children as safety and efficacy have not been established.

Drug Interactions

Drug-Drug interactions: Cedroin 90mg Injection may interact with certain medicines used to treat mood disorders (e.g. lithium), immunomodulatory medicines (thalidomide), diuretics (furosemide, torsemide), aminoglycosides (gentamycin, neomycin), antibiotics (erythromycin).

Drug-Food interactions: Avoid alcohol consumption and smoking to prevent unpleasant effects.

Drug-Disease interactions: Inform your doctor if you have conditions like kidney disease, liver problems, bone disorders, or musculoskeletal pain.

Drug-Drug Interactions Checker List

  • THALIDOMIDE
  • FUROSEMIDE
  • TORSEMIDE
  • GENTAMICIN
  • NEOMYCIN
  • LITHIUM

Habit Forming

No

Diet & Lifestyle Advise

  • Try to consume calcium and vitamin D in their diet as it helps make stronger bones and avoid everyday osteoporosis dangers.
  • Regular exercise like weight-bearing exercises are important for maintaining bone health.
  • Calcium is important for making bones strong. Vitamin D is equally important, which helps ensure calcium absorption and retention in bones, so take food high in calcium and vitamins.

Special Advise

  • Your doctor may suggest certain blood tests, like serum calcium, CBC, and kidney function tests, to check for any unpleasant effects.
  • Bone density scans are used to check bone mineral density (BMD).
  • Clinical monitoring of serum electrolyte concentrations may also be advised.

Disease/Condition Glossary

Hypercalcemia: Hypercalcemia is when the calcium level in the blood is higher than normal. Too much calcium in the blood can weaken the bones, create kidney stones, and interfere with working the heart and brain. It is usually a result of overactive parathyroid glands. Symptoms include increased thirst and urination, stomach pain, nausea, bone pain, muscle weakness, confusion and fatigue.

Paget's disease: Paget's disease is a chronic disease of bone that disrupts the replacement of old bone tissue with new bone tissue, resulting in the new bone that is abnormally shaped, weak and brittle. It most commonly occurs in the pelvis, skull, spine, and legs. Symptoms include bone pain, joint pain (especially in the back, hips, and knees), headache, enlargement and bowing of the thighs (femurs) and lower legs (tibias), and enlargement of the skull in the area of the forehead.

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Alcohol

Unsafe

Consuming alcohol while on treatment with Cedroin 90mg Injection is not recommended as it may result in unpleasant side effects or make you more susceptible to the effects of alcohol.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Cedroin 90mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Cedroin 90mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Cedroin 90mg Injection will be administered in the hospital setting. Hence, avoid driving vehicles.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Cedroin 90mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Cedroin 90mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Cedroin 90mg Injection is not recommended for children as the safety and effectiveness have not been established.

Country of origin

India
Other Info - CE85426

FAQs

Cedroin 90mg Injection is used to treat Hypercalcemia in Malignancy, Paget’s disease, and Osteolytic bone metastases of breast cancer.
Cedroin 90mg Injection contains Pamidronate as an active ingredient, which works by inhibiting osteoclast bone resorption that causes bone breakdown.
Cedroin 90mg Injection helps regulate the calcium level in the blood. This maintains bone formation and also helps the body to reverse bone loss. Due to this, the number of cells that damage bones becomes comparatively less.
Cedroin 90mg Injection will be administrated by a healthcare professional such as a doctor or a nurse. Do not self-administer.
The frequency of Cedroin 90mg Injection administration depends on the condition being treated. Therefore, follow your doctor's instructions for the best results.
Cedroin 90mg Injection is not recommended for pregnant women as it may cause fetal harm. It is unknown whether Cedroin 90mg Injection is excreted in human milk. Therefore, if you are a breastfeeding mother, please inform your doctor before taking Cedroin 90mg Injection.
Yes, Cedroin 90mg Injection may cause hair loss, but this is not a common side effect. If you experience hair loss while taking Cedroin 90mg Injection, please inform your doctor.
Cedroin 90mg Injection is safe if used under the supervision of a doctor. Follow your doctor’s instructions carefully and inform your doctor if you experience any side effects.
Maintain a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to support your overall health. Try to consume calcium and vitamin D in their diet as it helps make stronger bones and avoid everyday osteoporosis dangers. Regular exercise like weight-bearing exercises are important for maintaining bone health. Smoking can weaken bones, and excessive alcohol consumption can interfere with bone health. It's best to quit smoking and limit alcohol intake. Please consult your doctor if you have any concerns.
The common side effects of Cedroin 90mg Injection are injection site reactions, stomach pain, loss of appetite, nausea, vomiting, fever, headache, dizziness, mouth sores, constipation, and cough. If any of these side effects persist or worsen, please consult your doctor.

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