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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Casponex 50 Injection is used to treat fungal infections. It contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow. As a result, fungal cells get killed, or their growth is minimized.

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Composition :

CASPOFUNGIN-50MG

Manufacturer/Marketer :

Bharat Serums and Vaccines Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Casponex 50 Injection

Casponex 50 Injection belongs to the class of medicines known as 'antifungals' used to treat various fungal infections. A fungal infection is caused when a fungus invades and affects any body part.

Casponex 50 Injection contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow. As a result, fungal cells get killed, or their growth is minimized.

A qualified healthcare professional will administer Casponex 50 Injection. In some cases, you may experience certain common side effects, such as injection site reactions, headaches, dizziness, nausea, vomiting, diarrhoea, stomach pain, tremors, sweating, high blood pressure, difficulty sleeping and swelling of the hands, ankles, or feet. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Casponex 50 Injection, inform your doctor about your medical condition, sensitivities, and medications. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use any other medicines with Casponex 50 Injection without a doctor's recommendation. Casponex 50 Injection may cause dizziness; therefore, avoid driving vehicles or operating machinery until you return to normal. Avoid the consumption of alcohol while on Caspofungin therapy.

Uses of Casponex 50 Injection

Treatment of Fungal infections

Directions for Use

A qualified healthcare professional will administer Casponex 50 Injection. Kindly do not self-administer.

Medicinal Benefits

Casponex 50 Injection is an antifungal agent, a medicine used to treat several fungal infections. It can be used to treat fungal infections that other drugs have failed to treat. It is also used to treat serious fungal infections in persons who have a reduced immune system. Casponex 50 Injection works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its membrane formation. As a result, fungal cells get killed, or their growth is minimized.

How Casponex 50 Injection Works

Casponex 50 Injection contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow. As a result, fungal cells get killed, or their growth is minimized.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Casponex 50 Injection

  • Injection site reactions
  • Headache
  • Dizziness
  • Chills
  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach pain
  • Flushing
  • Tremor
  • Sweating
  • High blood pressure
  • Muscle ache,
  • Joint or bone pain
  • Difficulty sleeping
  • Swelling of the hands, ankles, or feet

What if I have taken an overdose of Casponex 50 Injection

Casponex 50 Injection is administered in a hospital setting under the supervision of your doctor or medical personnel. Thus, an overdose is quite improbable. While in the hospital, you will be constantly monitored to ensure that any unpleasant side effects are handled.

Drug Warnings

It is recommended not to use Casponex 50 Injection if you are allergic to any component present, so inform your doctor about your sensitivities with medicines and foods. Also, let your doctor know about your medical condition and the medications you are currently using. Do not use any other drugs with Casponex 50 Injection without a doctor’s recommendation. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Drug-Drug Interactions

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CaspofunginDexamethasone
Severe
CaspofunginPhenytoin
Severe

Drug-Drug Interactions

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CaspofunginDexamethasone
Severe
How does the drug interact with Casponex 50 Injection 1's:
Co-administration of Dexamethasone with Casponex 50 Injection 1's may cause Casponex 50 Injection 1's to be less effective.

How to manage the interaction:
Although there is a possible interaction between Casponex 50 Injection 1's and Dexamethasone, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
CaspofunginPhenytoin
Severe
How does the drug interact with Casponex 50 Injection 1's:
Coadministration of Phenytoin and Casponex 50 Injection 1's may decrease the blood levels of Casponex 50 Injection 1's, which may make Casponex 50 Injection 1's less effective.

How to manage the interaction:
Although taking Phenytoin and Casponex 50 Injection 1's together can result in an interaction, it can be taken if your doctor has prescribed it. If your infection gets worse or if your symptoms don't go away, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
CaspofunginRifampicin
Severe
How does the drug interact with Casponex 50 Injection 1's:
Taking Rifampicin in combination with Casponex 50 Injection 1's may make Casponex 50 Injection 1's less effective.

How to manage the interaction:
There may be a possibility of interaction between Casponex 50 Injection 1's and Rifampicin, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not stop using any medications without first talking to your doctor.
CaspofunginLeflunomide
Severe
How does the drug interact with Casponex 50 Injection 1's:
Leflunomide can cause liver problems, and combining it with other drugs, such as binimetinib, can raise the risk.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Casponex 50 Injection 1's, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include liver problems, fever, rash, itching, loss of appetite, dark urine, stomach pain, unusual bleeding or bruising, feeling tired, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
CaspofunginEfavirenz
Severe
How does the drug interact with Casponex 50 Injection 1's:
Taking Casponex 50 Injection 1's and Efavirenz together reduces the levels and effectiveness of Casponex 50 Injection 1's.

How to manage the interaction:
Although taking Casponex 50 Injection 1's and Efavirenz together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
CaspofunginNevirapine
Severe
How does the drug interact with Casponex 50 Injection 1's:
Using nevirapine together with Casponex 50 Injection 1's may cause Casponex 50 Injection 1's to be less effective.

How to manage the interaction:
Although there is a possible interaction between Casponex 50 Injection 1's and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
CaspofunginKetoconazole
Severe
How does the drug interact with Casponex 50 Injection 1's:
Coadministration of ketoconazole with Casponex 50 Injection 1's may raise the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Casponex 50 Injection 1's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medication without consulting a doctor.
CaspofunginCarbamazepine
Severe
How does the drug interact with Casponex 50 Injection 1's:
Taking carbamazepine and Casponex 50 Injection 1's together may result in decreasing the effects of Casponex 50 Injection 1's.

How to manage the interaction:
Although taking carbamazepine and Casponex 50 Injection 1's together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CaspofunginFosphenytoin
Severe
How does the drug interact with Casponex 50 Injection 1's:
Coadministration of Casponex 50 Injection 1's and Fosphenytoin can reduce the levels of Casponex 50 Injection 1's in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Casponex 50 Injection 1's and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It is advisable to follow a candida diet during fungal infections. This diet excludes sugar, gluten, certain dairy products, and alcohol. Switch to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very high sugar or high-carbohydrate diet may increase the count of Candida in some people.
  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of any disease.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Casponex 50 Injection Substitute

Substitutes safety advice
  • CANCIDAS 50MG INJECTION 10ML

    1262.80per tablet
  • CASPORAN 50MG INJECTION

    9222.40per tablet
  • Casfung 50mg Injection 1 ml

    4305.40per tablet
  • Caspogin 50 mg Injection 1's

    3788.40per tablet
  • CASPERCID 50MG INJECTION

    11806.11per tablet
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Alcohol

Caution

Avoiding alcohol is recommended to rule out any possibility of side effects.

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Pregnancy

Caution

Casponex 50 Injection is generally not recommended in pregnancy. Your doctor may prescribe this medicine if the benefit to the mother outweighs the potential risk to the fetus.

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Breast Feeding

Caution

If you are breastfeeding, please inform your doctor. It is not known if Casponex 50 Injection passes into breastmilk. Your doctor may advise you to stop breastfeeding before starting the treatment with Casponex 50 Injection.

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Driving

Caution

Casponex 50 Injection may cause dizziness; therefore, avoid driving vehicles or operating machinery until you return to normal.

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Liver

Caution

Inform your doctor before receiving the Casponex 50 Injection if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Casponex 50 Injection if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Please consult your doctor. Your doctor may prescribe this medicine if the benefits outweigh the risks.

FAQs

Casponex 50 Injection is used to treat Fungal infections.
Casponex 50 Injection contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow.
Casponex 50 Injection is not suitable for patients with known hypersensitivity to any components present in Casponex 50 Injection.
Casponex 50 Injection is unlikely to interfere with your contraception, including the combination pill or emergency contraception. For further information, seek medical advice from your healthcare professional.
Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, avoiding close direct contact until the infection is clear and avoiding sharing things with the infected person is recommended, as it can also spread the infection.
No, you can continue to eat and drink normally while taking Casponex 50 Injection unless instructed by the doctor.
No, Casponex 50 Injection is not an antibiotic. It belongs to the class of medicines called antifungals.
Casponex 50 Injection is administered as a slow intravenous injection, usually once a day, by a qualified healthcare professional. The injection is given over about one hour. The dosage and treatment duration will be determined by your doctor based on your specific condition. Do not self-administer.
Casponex 50 Injection targets fungal infections. It works by inhibiting the growth of the fungi, helping to treat conditions like candidemia (bloodstream infection) and invasive aspergillosis (serious infection by aspergillus fungus, in the lungs).
Casponex 50 Injection is effective when used as per the dosage and duration recommended by a doctor. Do not self-medicate.
Casponex 50 Injection causes side effects such as injection site reactions, headache, dizziness, chills, nausea, vomiting, diarrhoea, stomach pain tremor, high blood pressure, swelling of hands, ankles, or feet and difficulty sleeping. Please, consult a doctor if these persist for longer durations.

Country of origin

India

Manufacturer/Marketer address

17Th Floor, Hoechst House, Nariman Point, Mumbai 400 021, Maharashtra, India.
Other Info - CAS0142

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