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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Dec 13, 2024 | 11:24 AM IST
Carinase 15 MIU Injection belongs to a class of drugs called antithrombotic agents. It is used in the treatment of blood clots mainly in conditions like peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis, cerebral infarction (stroke), and myocardial infarction (heart attack). This medicine works by converting plasminogen to the plasmin enzyme, which dissolves the blood clots, thus restoring the blood flow to the affected area.
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Prescription drug

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Manufacturer/Marketer

Health Biotech Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Carinase 15 MIU Injection

Carinase 15 MIU Injection belongs to a class of drugs called antithrombotic agents used to dissolve harmful blood clots in blood vessels. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction (heart attack),  and pulmonary embolism (blood clots in the lungs).

Carinase 15 MIU Injection contains urokinase that works by converting plasminogen to the enzyme plasmin. Plasmin degrades fibrin clots as well as fibrinogen and some other plasma proteins. It effectively dissolves the blood clots, restoring the blood flow to the affected area.

Carinase 15 MIU Injection will be administered by a healthcare professional. In some cases, Carinase 15 MIU Injection may cause unusual bleeding, nausea, vomiting, and loss of appetite. Most of these side effects do not necessitate medical treatment and fade away with time. Please visit your doctor if the side effects persist or worsen.

If you are pregnant or breastfeeding, inform your doctor before taking Carinase 15 MIU Injection. Keep your doctor updated on your medical condition and medications to rule out any potential interactions. Avoid consuming alcohol along with Carinase 15 MIU Injection as it could increase the risk of bleeding. Carinase 15 MIU Injection should not be given to children because its safety and effectiveness have not been proven.

Uses of Carinase 15 MIU Injection

Treatment of Blood clots

Medicinal Benefits

Carinase 15 MIU Injection belongs to a class of drugs known as antithrombotic medications. Carinase 15 MIU Injection contains urokinase. It works by dissolving or lysing the harmful or unwanted blood clots in the blood vessels. Thus it restores the blood flow to the affected blood vessels, preventing various illnesses caused by blood clots. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction (heart attack),  and pulmonary embolism (blood clots in the lungs).

Directions for Use

Carinase 15 MIU Injection is given as an intravenous (into a vein) injection by a doctor or nurse. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Carinase 15 MIU Injection

  • Unusual bleeding
  • Nausea
  • Vomiting
  • Loss of appetite

Drug Warnings

Before taking Carinase 15 MIU Injection, tell your doctor if you are pregnant or breastfeeding. Carinase 15 MIU Injection should be used with caution in elderly people because they are at significant risk of bleeding. If you have active tuberculosis, stomach ulcers, severe uncontrolled arterial hypertension, bleeding abnormalities, severe hepatic or renal diseases, inform your doctor before taking Carinase 15 MIU Injection. Also, let your doctor know if you have had a recent cerebrovascular accident, as well as intracranial or intraspinal surgery. Inform your doctor that you take Carinase 15 MIU Injection if are due to undergo surgery. You should avoid alcohol because it increases the risk of bleeding. Carinase 15 MIU Injection is not recommended for children since its safety and effectiveness have not been proven.

Drug Interactions

Drug-Drug Interactions: Carinase 15 MIU Injection may interact with anticoagulant medications (warfarin) and medications with platelet antiaggregant effects (aspirin, ticlopidine hydrochloride, dipyridamole).

Drug-Food Interactions: Alcohol should be avoided because it increases the risk of bleeding.

Drug-Disease Interactions: Carinase 15 MIU Injection may have an interaction with disease conditions like active bleeding, severe uncontrolled arterial hypertension, recent surgery (CPR/intracranial/intraspinal surgery within two months), bleeding diathesis (a tendency to bleed), history of cerebrovascular accident, and intracranial defect (arteriovenous malformation, aneurysm, neoplasm).

Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • TICLOPIDINE HYDROCHLORIDE
  • DIPYRIDAMOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid cranberry juice, grapefruit juice, noni juice, pomegranate juice, and green tea.
  • Make no dietary changes without first consulting your doctor.
  • You should avoid alcohol because it increases the risk of bleeding.
  • Maintain a healthy cholesterol and triglyceride level.
  • Maintain a healthy weight and exercise routine to keep your heart healthy.

Disease/Condition Glossary

Blood Clot: A blood clot is a clump or mass of blood formed when platelets, proteins, and cells in the blood adhere to one another. When you are injured, your body creates a blood clot to stop the bleeding. Though blood clots are helpful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart or lungs and result in severe conditions. Obesity, smoking, cancer, a family history of blood clots, age over 65, and certain birth control pills or pregnancy are common risk factors for blood clots.

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Alcohol

Unsafe

Avoid the consumption of alcohol with Carinase 15 MIU Injection as it may increase the risk of bleeding.

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Pregnancy

Unsafe

Carinase 15 MIU Injection is not recommended during pregnancy or immediately after the delivery unless advised by the doctor. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Carinase 15 MIU Injection. Please consult a doctor if you have any concerns.

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Driving

Caution

It is unclear whether Carinase 15 MIU Injection impacts your ability to drive or operate machinery. However, drive or operate machinery only if you are alert.

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Liver

Caution

Let your doctor know if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Let your doctor know if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Carinase 15 MIU Injection is not recommended for children as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7Th To 12Th Floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103.
Other Info - CA66048

Author Details

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FAQs

Carinase 15 MIU Injection belongs to a class of drugs called antithrombotic agents used to dissolve harmful blood clots in blood vessels. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction and pulmonary embolism (blood clots in the lungs).
Carinase 15 MIU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected blood vessels, preventing various illnesses caused by blood clots.
Yes, Carinase 15 MIU Injection raises the possibility of bleeding. Always exercise caution when engaging in activities that could result in an injury or bleeding. Notify your doctor right away if you notice any unusual bruises or bleeding.
To determine blood clotting time, tests such as platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalised ratio) are utilised.
If you are scheduled for surgery, please consult your doctor. The doctor may advise you to stop taking Carinase 15 MIU Injection a few days before surgery because it increases the chance of bleeding during surgery.
Carinase 15 MIU Injection is not recommended for use in people with severe uncontrolled high blood pressure.
Carinase 15 MIU Injection may interact with certain medications such as anticoagulant medications (warfarin) and medications with platelet antiaggregant effects (aspirin, ticlopidine hydrochloride, dipyridamole). So, avoid taking these medications together. However, it is better to consult a doctor before taking any medication while on treatment with Carinase 15 MIU Injection to ensure safety.
The common side effects of Carinase 15 MIU Injection that may occur in some individuals such as unusual bleeding, nausea, vomiting, and loss of appetite. Most of these side effects do not necessitate medical treatment and fade away with time. Please visit your doctor if the side effects persist or worsen.

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