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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:27 PM IST
Cardivas IN 12.5/5 mg Tablet is an antihypertensive medicine used to treat hypertension (high blood pressure). It is also effective in treating moderate to severe heart failure and angina (heart-related chest pain), thereby reducing the risk of heart attack or stroke in adults. It contains Carvedilol and Ivabradine. Carvedilol acts by relaxing blood vessels by blocking the action of certain natural substances like epinephrine or adrenaline. Ivabradine works by reducing the heart rate by a few beats per minute.  In this way, it lowers the heart's oxygen requirement, especially when an angina attack can happen. Thus, it lowers the raised blood pressure and keeps the heartbeat slowly and with less force, reducing the risk of having a stroke, a heart attack, or other heart problems.
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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Cardivas IN 12.5/5 mg Tablet

Cardivas IN 12.5/5 mg Tablet belongs to a group of antihypertensive medicines used to treat hypertension (high blood pressure). It is also effective in treating moderate to severe heart failure and angina (heart-related chest pain), thereby reducing the risk of heart attack or stroke in adults. High blood pressure is a condition in which the force of blood against the artery walls is very high. It will be an addition to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly and damage the heart, brain, and kidneys' blood vessels, resulting in heart failure, stroke, or kidney failure.

Cardivas IN 12.5/5 mg Tablet contains Carvedilol and Ivabradine combination. Carvedilol acts by relaxing blood vessels by blocking the action of certain natural substances like epinephrine or adrenaline. Ivabradine works by reducing the heart rate by a few beats per minute.  In this way, it lowers the heart's requirement for oxygen, especially in situations where an angina attack can happen. Thus, it lowers the raised blood pressure and keeps the heartbeat slowly reducing with less force, reducing the risk of having a stroke, a heart attack, or other heart problems.

Cardivas IN 12.5/5 mg Tablet should be taken as prescribed. The dose of the medicine will be decided by your doctor based on your medical condition. In some cases, Cardivas IN 12.5/5 mg Tablet may cause certain side effects such as diarrhoea, headache, weight gain, slow heartbeat, dry eyes, tiredness, dizziness, or low blood pressure. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Cardivas IN 12.5/5 mg Tablet should be avoided if allergic to it. If you are pregnant or breastfeeding, please inform your doctor before taking this medicine. Avoid taking Cardivas IN 12.5/5 mg Tablet if you have bronchitis, asthma, emphysema (a lung condition causing shortness of breath), severe liver disease, heart block, slow heart rate, or sick sinus syndrome (abnormal heart rhythms caused by malfunction of the heart’s natural pacemaker). Cardivas IN 12.5/5 mg Tablet is not recommended for children below 18 years of age. Inform your doctor if you have diabetes, coronary artery disease, fluid retention, thyroid disorder, angina (chest pain), kidney disease, slow heartbeats, Raynaud’s syndrome (a circulatory problem), or pheochromocytoma (tumor in the adrenal glands), or undergoing any surgery. 

Uses of Cardivas IN 12.5/5 mg Tablet

Treatment of Hypertension (high blood pressure), Angina (heart-related chest pain), and Myocardial infarction (heart failure)

Medicinal Benefits

Cardivas IN 12.5/5 mg Tablet contains Carvedilol in the controlled release form and Ivabradine. Carvedilol plays a vital role in relaxing blood vessels by blocking the action of certain natural substances in your body. Thus, it lowers blood pressure and reduces the risk of having a stroke, a heart attack or other heart problems. Ivabradine works by reducing the heart rate by a few beats per minute.  In this way, it lowers the heart's requirement for oxygen, especially in situations where an angina attack can happen.

Directions for Use

Take this medicine with or without food as advised by the doctor. Swallow it as a whole with a glass of water daily at the same time for effective results. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cardivas IN 12.5/5 mg Tablet

  • Diarrhoea
  • Headache
  • Weight gain
  • Slow heartbeat
  • Dry eyes
  • Tiredness
  • Dizziness
  • Low blood pressure

Drug Warnings

If you are allergic to Cardivas IN 12.5/5 mg Tablet or any other medicines, please tell your doctor. Cardivas IN 12.5/5 mg Tablet is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Cardivas IN 12.5/5 mg Tablet . If you are about to undergo any surgery, you are advised to inform your doctor that you are taking Cardivas IN 12.5/5 mg Tablet . Avoid taking Cardivas IN 12.5/5 mg Tablet if you have bronchitis, asthma, emphysema (a lung condition causing shortness of breath), severe liver disease, heart block, slow heart rate, or sick sinus syndrome (abnormal heart rhythms caused by malfunction of the heart’s natural pacemaker). If you have diabetes, coronary artery disease, fluid retention, thyroid disorder, angina (chest pain), kidney disease, slow heartbeats, Raynaud’s syndrome (a circulatory problem), or pheochromocytoma (tumor in the adrenal glands), inform your doctor before taking Cardivas IN 12.5/5 mg Tablet .

Drug Interactions

Drug-Drug Interactions: Cardivas IN 12.5/5 mg Tablet may have interaction with pain killers (aspirin), calcium channel blockers (amlodipine), water pills (furosemide, hydrochlorothiazide), and thyroid medicines (levothyroxine).

Drug-Food Interactions: Cardivas IN 12.5/5 mg Tablet may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Cardivas IN 12.5/5 mg Tablet as it may increase the levels of Cardivas IN 12.5/5 mg Tablet in the blood. Also, avoid sodium, potassium, magnesium, and calcium-rich foods with Cardivas IN 12.5/5 mg Tablet as they may reduce the effect of Cardivas IN 12.5/5 mg Tablet .

Drug-Disease Interactions: Avoid taking Cardivas IN 12.5/5 mg Tablet if you have bronchitis, asthma, emphysema (a lung condition causing shortness of breath), severe liver disease, heart block, slow heart rate, or sick sinus syndrome (abnormal heart rhythms caused by malfunction of heart’s natural pacemaker). If you have diabetes, coronary artery disease, fluid retention, thyroid disorder, angina (chest pain), kidney disease, slow heartbeats, Raynaud’s syndrome (a circulatory problem), or pheochromocytoma (tumor in the adrenal glands), inform your doctor before taking Cardivas IN 12.5/5 mg Tablet .

Drug-Drug Interactions Checker List

  • ASPIRIN
  • AMLODIPINE
  • FUROSEMIDE
  • LEVOTHYROXINE
  • HYDROCHLOROTHIAZIDE
  • LORAZEPAM
  • DULOXETINE
  • PREGABALIN

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress by changing your expectations and the way you react in certain situations, and do activities that you enjoy by making time for yourself.
  • Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil, which may help in lowering high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Special Advise

  • Monitor your blood pressure regularly, and if you notice any fluctuations, please consult a doctor.
  • A low salt diet and regular exercise are recommended along with Cardivas IN 12.5/5 mg Tablet for effective results.

Disease/Condition Glossary

Hypertension: Blood pressure is the measurement of the force that the heart uses to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Normal blood pressure lies between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.

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Alcohol

Unsafe

Avoid consumption of alcohol with Cardivas IN 12.5/5 mg Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before taking Cardivas IN 12.5/5 mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Cardivas IN 12.5/5 mg Tablet is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before taking Cardivas IN 12.5/5 mg Tablet . Your doctor may suggest you to stop feeding while on treatment with this medicine.

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Driving

Unsafe

Cardivas IN 12.5/5 mg Tablet may cause dizziness or tiredness in some people. Therefore, avoid driving if you feel dizzy or tired after taking Cardivas IN 12.5/5 mg Tablet .

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Cardivas IN 12.5/5 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Cardivas IN 12.5/5 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Cardivas IN 12.5/5 mg Tablet is not recommended for use in children and adolescents below 18 years as the safety and effectiveness are not established.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001.
Other Info - CAR1325

FAQs

Cardivas IN 12.5/5 mg Tablet is used to treat Hypertension (high blood pressure), Angina (heart-related chest pain), and Myocardial infarction (heart failure).
Cardivas IN 12.5/5 mg Tablet contains Carvedilol and Ivabradine combination. Carvedilol acts by relaxing blood vessels by blocking the action of certain natural substances like epinephrine or adrenaline. Ivabradine works by reducing the heart rate by a few beats per minute. Â In this way, it lowers the heart's requirement for oxygen, especially in situations where an angina attack can happen.Â
You are recommended to avoid sodium, potassium, magnesium and calcium-rich foods with Cardivas IN 12.5/5 mg Tablet as they may reduce the effect of Cardivas IN 12.5/5 mg Tablet . Also, avoid intake of grapefruit juice with Cardivas IN 12.5/5 mg Tablet as it may increase the levels of Cardivas IN 12.5/5 mg Tablet in the blood and cause adverse effects.
Do not take more than the prescribed dose of Cardivas IN 12.5/5 mg Tablet as it may cause Cardivas IN 12.5/5 mg Tablet overdose resulting in symptoms such as dizziness, fits, fainting, weakness, bluish-coloured fingernails, uneven heartbeats and shortness of breath. However, if you experience any of these symptoms while taking Cardivas IN 12.5/5 mg Tablet , please consult a doctor immediately.
No, you should not stop taking Cardivas IN 12.5/5 mg Tablet on your own. Abrupt discontinuation can cause a rise in your blood pressure suddenly, which increases the risk of heart attack and stroke. So complete the full course of treatment as prescribed by your doctor.
Cardivas IN 12.5/5 mg Tablet should be taken as prescribed by your doctor. But preferably at the same time each day. It can be taken with or without food, but it's important to follow your doctor's specific instructions regarding the timing and dosage.
Cardivas IN 12.5/5 mg Tablet generally starts to work within 1-2 hours after taking the dose, with the full effect typically seen within 1-2 days. However, it may take several weeks to notice a significant improvement in symptoms.
Stopping Cardivas IN 12.5/5 mg Tablet suddenly can lead to a sudden increase in heart rate and blood pressure, which may increase the risk of heart-related complications such as heart attack or stroke. Therefore take the advice of your doctor before stopping Cardivas IN 12.5/5 mg Tablet .
Yes, you can experience tired, when you take Cardivas IN 12.5/5 mg Tablet as a side effect. It does not require medical attention and gradually resolves over time.
Cardivas IN 12.5/5 mg Tablet is generally not associated with long-term weight gain. Some patients might experience a slight weight gain when they first start using Cardivas IN 12.5/5 mg Tablet , but this usually stabilizes after the body adjusts, typically within a few months and it can be adjusted by maintaining a balanced diet. If you notice any significant or sudden weight gain, consult your doctor.
Cardivas IN 12.5/5 mg Tablet is generally used cautiously in patients with kidney disorders. While no dose alteration is usually required, it's important to monitor kidney function regularly while using this medication. If you have pre-existing kidney issues, inform your doctor before starting Cardivas IN 12.5/5 mg Tablet .
If you are suffering with diabetic, you are recommended to inform your doctor, before taking Cardivas IN 12.5/5 mg Tablet as Cardivas IN 12.5/5 mg Tablet can help manage high blood pressure and heart conditions, which are common concerns for diabetic patients. However, it's important to monitor blood sugar levels closely, because carvedilol can sometimes make it harder to recognize low blood sugar symptoms.
Yes, you can take Cardivas IN 12.5/5 mg Tablet with or without food. However, it's important to take it at the same time each day, as prescribed by your doctor.
Serious side effects of Cardivas IN 12.5/5 mg Tablet are slow or irregular heartbeats, chest pain or discomfort, shortness of breath, severe dizziness or fainting and severe allergic reactions. If you experience any of these side effects. Stop taking Cardivas IN 12.5/5 mg Tablet and consult your doctor immediately.
Avoid taking Cardivas IN 12.5/5 mg Tablet if you have bronchitis, asthma, emphysema (a lung condition causing shortness of breath), severe liver disease, heart block, slow heart rate, or sick sinus syndrome (abnormal heart rhythms caused by malfunction of the heart’s natural pacemaker). If you have diabetes, coronary artery disease, fluid retention, thyroid disorder, angina (chest pain), kidney disease, slow heartbeats, Raynaud’s syndrome (a circulatory problem), or pheopheochromocytoma (tumour in the adrenal glands), inform your doctor before taking Cardivas IN 12.5/5 mg Tablet . Also let your doctor know if you are breastfeeding, pregnant or planning pregnancy to avoid possible interactions.
The common side effects of Cardivas IN 12.5/5 mg Tablet are diarrhoea, headache, weight gain, slow heartbeat, dry eyes, tiredness, dizziness, or low blood pressure. If any of these side effects persist or worsen, please consult your doctor.

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