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Carbozest 450 Injection 45 ml

Carbozest 450 Injection 45 ml

Prescription drug
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Composition

CARBOPLATIN-10MG

Manufacturer/Marketer

Zee Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Carbozest 450 Injection

Carbozest 450 Injection belongs to a group of anti-cancer medicines used for the treatment of ovarian cancer and small-cell lung cancer. It may sometimes be used to treat other cancers. Cancer forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

Carbozest 450 Injection contains 'Carboplatin'. Carboplatin acts by penetrating the cell wall and binding to the cell's DNA, stopping the cell from naturally dividing and functioning, ultimately destroying the cell. These medicines target cancer cells because they often affect rapidly dividing cells.

Carbozest 450 Injection is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection. You may experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses and electrolyte disturbances. Most of these side effects of Carbozest 450 Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Carbozest 450 Injection for as long as your doctor has prescribed. Do not stop the Carbozest 450 Injection midway. Talk to your doctor before taking Carbozest 450 Injection if you have severe allergic reactions to Carbozest 450 Injection or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Carbozest 450 Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Carbozest 450 Injection if you are pregnant or breastfeeding because this Carbozest 450 Injection can cause harmful effects on the unborn baby. Both women and men using this Carbozest 450 Injection should use birth control to avoid pregnancy.

Uses of Carbozest 450 Injection

Treatment of Ovarian cancer and Small cell lung cancer

Medicinal Benefits

Carbozest 450 Injection contains 'Carboplatin' which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or with other chemotherapy drugs depending on your cancer type.

Directions for Use

Parenteral: Carbozest 450 Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Carbozest 450 Injection

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Hair loss and numbness
  • Tingling
  • Burning
  • Pain in the hands or feet
  • Nephrotoxicity at high doses
  • Electrolyte disturbances
  • Thrombocytopenia (low blood platelet count)
  • Peripheral neuropathy (nerves malfunction)
  • Leukopenia (low white blood cell count)

Drug Warnings

Carbozest 450 Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Carbozest 450 Injection. To treat your condition effectually, continue taking Carbozest 450 Injection for as long as your doctor has prescribed. Do not stop the Carbozest 450 Injection midway. Talk to your doctor before taking Carbozest 450 Injection if you have severe allergic reactions to Carbozest 450 Injection or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Carbozest 450 Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Carbozest 450 Injection if you are pregnant or breastfeeding because this Carbozest 450 Injection can cause harmful effects on the unborn baby. Both women and men using this Carbozest 450 Injection should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Carbozest 450 Injection treatment and appropriate until recovery is achieved.

Drug Interactions

Drug-Drug Interactions: Carbozest 450 Injection interacts with medicines used in the treatment of chemotherapy (e.g. pemetrexed, gemcitabine, pegfilgrastim, paclitaxel, docetaxel), antacid medications (e.g. pantoprazole) and antibiotic medications (e.g. amikacin, gentamicin, kanamycin, streptomycin, tobramycin).

Drug-Food Interactions: No food interaction was found.

Drug-Disease Interactions: Inform your doctor before taking Carbozest 450 Injection it requires close monitoring if you are suffering from Infection (bacterial/fungal/protozoal/viral), bleeding disorders, bone marrow depression/low blood counts, fever, renal dysfunction or disorders, peripheral neuropathy (nerves malfunction).

Drug-Drug Interactions Checker List

  • PEMETREXED
  • GEMCITABINE
  • PEGFILGRASTIM
  • PACLITAXEL
  • PANTOPRAZOLE
  • AMIKACIN
  • GENTAMICIN
  • KANAMYCIN
  • STREPTOMYCIN
  • TOBRAMYCIN
  • DOCETAXEL

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Special Advise

  • Peripheral blood counts should be frequently monitored during carboplatin treatment and, when appropriate, until recovery is achieved.
  • Carbozest 450 Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Carbozest 450 Injection.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Carbozest 450 Injection may make your skin sensitive to sunlight.

Disease/Condition Glossary

Ovarian cancer: Cancer that forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Carbozest 450 Injection. It could lead to avoiding unpleasant side effects.

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Pregnancy

Unsafe

Carbozest 450 Injection should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Carbozest 450 Injection and at least six months afterwards. Please consult your doctor about any concerns regarding this.

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Breast Feeding

Unsafe

Carbozest 450 Injection should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers. Please consult your doctor about any concerns regarding this.

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Driving

Caution

Carbozest 450 Injection may affect your reactions and your ability to drive. Possible side effects of chemotherapy with Carbozest 450 Injection may occur, such as nausea and vomiting. If you are affected by these side effects, you should not drive and/or operate machines that require you to be alert.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Carbozest 450 Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Carbozest 450 Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Children

Unsafe

Efficacy and safety have not been established. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing them.

Country of origin

India

Manufacturer/Marketer address

Uchani, G.T. Road, Karnal-132001 Haryana (India).
Other Info - CAR1679

Author Details

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FAQs

Carbozest 450 Injection is used to treat ovarian cancer and small-cell lung cancer.
Carbozest 450 Injection contains 'Carboplatin'. Carboplatin works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.
Yes, Carbozest 450 Injection can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.
Carbozest 450 Injection should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.
Before you receive treatment with Carbozest 450 Injection, tell your doctor about all of your medical conditions. You should not receive Carbozest 450 Injection if you are allergic to carboplatin or any contents in Carbozest 450 Injection. It should not be employed in patients with severe bone marrow depression or significant bleeding.
If not given an inappropriate dose, Carbozest 450 Injection can cause toxic effects, although not everyone gets it. So, Carbozest 450 Injection is prescribed by a doctor experienced in the use of medications to treat cancer only.
Avoid taking Carbozest 450 Injection if you are pregnant because Carbozest 450 Injection can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of Carbozest 450 Injection.

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