Cafe 500mg Tablet is used to treat or prevent certain infections caused by bacteria. It is prescribed for the treatment of pneumonia, gonorrhoea (a sexually transmitted disease), typhoid fever (a serious infection that is common in developing countries), infectious diarrhoea (infections that cause severe diarrhoea), and infections of the skin, bone, joint, abdomen (stomach area), and prostate (male reproductive gland).

Cafe 500mg Tablet contains an antibiotic, 'Ciprofloxacin', which is bactericidal in nature and works by killing bacteria that cause infections. It prevents the division of bacterial cells. It also inhibits the repair of bacterial cells. Altogether, it kills the bacteria.

Cafe 500mg Tablet should be taken in the dose and duration as advised by your doctor. In some cases, you may experience nausea, diarrhoea, abnormal liver function tests, vomiting, and rash. Most of these side effects of Cafe 500mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

It is not advisable to stop this medicine suddenly to avoid unpleasant side effects. Inform your doctor if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant or breastfeeding. If you experience any symptoms of an allergic reaction such as rashes, itching, swelling, shortness of breath, etc. you should contact a doctor immediately. 

Cafe 500mg Tablet contains the antibiotic Ciprofloxacin, which helps treat and prevent a wide range of bacterial infections. It is bactericidal in nature and works by killing bacteria that cause infections. It prevents the division of bacterial cells and inhibits the repair of bacterial cells. Both these actions lead to the killing of the bacteria. 

• Nausea
• Diarrhoea
• Vomiting
• Rash
• Liver function tests abnormal
• Change of the heart rhythm (ECG)
• Low blood potassium level

Do not take Cafe 500mg Tablet if you are allergic or have had a severe reaction to ciprofloxacin or any other quinolone or fluoroquinolone antibiotic such as delafloxacin gemifloxacin, levofloxacin, moxifloxacin and ofloxacin. Taking Cafe 500mg Tablet may increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Inform your doctor if you have or have ever had a kidney, heart, or lung transplant, kidney disease, a joint or tendon disorder such as rheumatoid arthritis (auto immune disorder of joints causing pain, swelling, and loss of function), seizures (fits), epilepsy or if you participate in regular physical activity. Taking Cafe 500mg Tablet may worsen muscle weakness in people with myasthenia gravis (a disorder of the nervous system that causes muscle weakness) and cause severe difficulty breathing or death. Dairy products should be avoided along with Cafe 500mg Tablet. And also, exposure to sunlight should be avoided while taking Cafe 500mg Tablet as it may cause increased phototoxicity or photosensitivity. Patients with epilepsy, and irregular heartbeat (especially a condition known as QT prolongation) should tell their doctor before taking Cafe 500mg Tablet.

Drug-drug interactions: This medicine may have an interaction with blood thinners (such as warfarin), antidepressants and antipsychotics (like clozapine, olanzapine), caffeine-containing medications, insulin or other anti-diabetic medications (like chlorpropamide, glimepiride, glipizide, glyburide, tolazamide, and tolbutamide), medications for regulating irregular heartbeat (like amiodarone, disopyramide, procainamide, quinidine), pain killers (like ibuprofen and naproxen).

Drug-Food Interactions:  Cafe 500mg Tablet interacts with dairy products (like milk or yoghurt) or calcium-fortified juices alone.

Drug-Disease Interactions: Inform your doctor if you have or have ever had a kidney, heart, or lung transplant, kidney disease, a joint or tendon disorder such as rheumatoid arthritis (a condition in which the body attacks its joints, causing pain, swelling, and loss of function), seizures, epilepsy or if you participate in regular physical activity before starting Cafe 500mg Tablet.

• WARFARIN
• CLOZAPINE
• OLANZAPINE
• CHLORPROPAMIDE
• GLIMEPIRIDE
• GLIPIZIDE
• GLYBURIDE
• TOLAZAMIDE
• TOLBUTAMIDE
• AMIODARONE
• DISOPYRAMIDE
• PROCAINAMIDE
• QUINIDINE
• IBUPROFEN
• NAPROXEN

• Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate. Cafe 500mg Tablet may increase nervousness, sleeplessness and anxiety caused by caffeine.

• Probiotics should be taken after taking the full course of Cafe 500mg Tablet to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria. 

• Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. Make sure you drink plenty of water or other fluids daily while taking Cafe 500mg Tablet.

• Avoid intake of alcoholic beverages with Cafe 500mg Tablet as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Cafe 500mg Tablet in fighting off infections.

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. A few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. However, people with weak immune systems or taking immunosuppressive medicine can be more prone to bacterial infection.