Cabolong 40 Tablet 30's
₹6851.2*
MRP ₹8564
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Cabolong 40 Tablet is an anti-cancer medicine used in the treatment of renal cell carcinoma. It is a disease in which cancer cells grow uncontrollably in the kidney and form a tumor. Cabolong 40 Tablet is used in treating advanced renal cell carcinoma as first-line therapy for advanced renal cell carcinoma in combination with nivolumab and hepatocellular carcinoma in patients who have previously been treated with sorafenib.
Cabolong 40 Tablet contains Cabozantinib as an active ingredient, which belongs to the class of medicines known as kinase inhibitors. It works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells.
Cabolong 40 Tablet may cause certain side effects such as diarrhea, decreased appetite, nausea, vomiting, increased blood pressure, muscle cramps, decreased weight, dizziness, and constipation. Inform your doctor if any of these side effects bother you. Cabolong 40 Tablet should be taken as advised by your doctor.
Avoid taking Cabolong 40 Tablet if you are allergic to it or any other components of it. Before taking Cabolong 40 Tablet , inform your doctor if you have/had liver or kidney disease, gastrointestinal disorders, heart problems, blood or bleeding disorders, open or healing wounds, and a history of recent surgery. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding.
Cabolong 40 Tablet contains Cabozantinib, which is used in treating advanced renal cell carcinoma and liver cancer. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor. In this way, Cabolong 40 Tablet stops the body's production, spread and growth of cancerous cells.
To treat your condition effectually, continue taking Cabolong 40 Tablet for the period that your doctor has prescribed. Caution should be exercised if you have/had liver or kidney disease, any planned surgery, heart disease, blood or bleeding disorders, open/healing of wound, or gastrointestinal disorders. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Cabolong 40 Tablet may cause hypertension, thrombotic events, hemorrhagic events, gastrointestinal perforation and fistula, Reversible Posterior Leukoencephalopathy Syndrome (RPLS), hepatotoxicity, severe diarrhoea, Osteonecrosis of the jaw (ONJ), Palmar-Plantar Erythrodysesthesia (PPE), adrenal insufficiency, impaired wound healing, and proteinuria in some patients. Hence, inform your doctor about your complete medication and medical history before taking Cabolong 40 Tablet . Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause dizziness. This medicine is not recommended for use in children below 18 years of age as the safety and efficacy are not established.
Drug-Drug Interactions: Cabolong 40 Tablet may have interaction with strong CYP3A4 inhibitors (clarithromycin, diltiazem, erythromycin, itraconazole, ketoconazole, ritonavir), strong CYP3A4 inducers (carbamazepine, rifampicin, phenytoin, phenobarbitone, dexamethasone).
Drug-Food Interactions: Avoid alcohol consumption and smoking.
Dug-Disease Interactions: Tell your doctor if you have liver or kidney disease, heart problems, GI perforation, thyroid dysfunction, or thromboembolism before starting the treatment.
Renal Cell Carcinoma: Also known as kidney cancer. It is the most common type of cancer seen in adults. This condition occurs when cancer/ malignant cells grow uncontrollably in the kidney and form a tumor. Advanced kidney cancer (metastatic renal cell carcinoma) occurs when the malignant cells spread to other parts of the body. Symptoms include red, orange, or pink-coloured urine due to the presence of blood in the urine.
Hepatocellular carcinoma: Also known as liver cancer. It occurs when the cancer/ malignant cells grow out of control. This infects the liver, destroys the liver cells and affects the ability of the liver to work properly. Symptoms may include abdominal pain, loss of appetite, weight loss, and pale bowel motions.
Alcohol
Caution
Avoid consumption of alcohol while on treatment with Cabolong 40 Tablet as it may cause serious side effects.
Pregnancy
Unsafe
Cabolong 40 Tablet is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Cabolong 40 Tablet . You should not become pregnant while you are taking Cabolong 40 Tablet for at least four months from the last dose of Cabolong 40 Tablet . Using effective birth control methods while on treatment is suggested.
Breast Feeding
Unsafe
Cabolong 40 Tablet should not be taken if you are breastfeeding as it passes into breast milk and may harm your infant. Avoid nursing your child while on treatment with this medicine and for at least four months from the last dose of medicine.
Driving
Unsafe
In some cases, Cabolong 40 Tablet may cause dizziness and visual problems. As a result, do not drive, operate machinery, or engage in any activity that requires clear vision until you are satisfied you can drive while on Cabolong 40 Tablet therapy.
Liver
Caution
If you have a pre-existing or a history of liver problems, tell your doctor before taking this medicine. Cabolong 40 Tablet is known to cause hepatotoxicity when taken in combination with nivolumab. Hence, this medicine should be taken cautiously in patients with moderate liver impairment. Your doctor may suggest tests to monitor your liver function while on treatment with this medicine.
Kidney
Caution
If you have a pre-existing or a history of kidney diseases, inform your doctor before taking Cabolong 40 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
Unsafe
Cabolong 40 Tablet is not recommended for use in children as the safety and efficacy are not established.
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