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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Butodol Injection 1 ml is used to treat moderate to severe pain. It contains Butorphanol which works by blocking the transmission of pain signals and changing the way body senses pain. In some cases, this medicine may cause side effects such as headache, dizziness, sleepiness, vomiting, nausea, and constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

BUTORPHANOL-1MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Butodol Injection 1 ml

Butodol Injection 1 ml belongs to the class of 'narcotic analgesics' primarily used to treat moderate to severe pain post-surgery, muscle pain, and migraine-related headaches. Butodol Injection 1 ml is also used as an anaesthesia adjunct during surgery and early labor. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. 

Butodol Injection 1 ml contains 'Butorphanol' which works by blocking the transmission of pain signals located in the brain that controls pain, pleasure, and addictive behaviors. Butorphanol also acts as a pre-anaesthetic during surgery, antitussive (cough suppressant), and antiemetic (prevents vomiting) medication.

Use this medicine as prescribed by your doctor. Your doctor will decide the dose and duration based on the severity of your pain and response to treatment. Common side effects of Butodol Injection 1 ml include headache, dizziness, sleepiness, vomiting, nausea, and constipation. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor beforehand if you have liver, kidney, or heart diseases, breathing problems, mood disorders, brain-related problems, gastrointestinal disorders, underactive thyroid (hypothyroidism), drug addiction, and urination problems before starting Butodol Injection 1 ml. It is essential to let your doctor know if you are pregnant, planning to conceive, or a breastfeeding mother. Butodol Injection 1 ml causes dizziness and drowsiness, so do not drive or operate machinery until you are mentally alert. Avoid alcohol to further prevent the worsening of side effects. Butodol Injection 1 ml is not recommended for people below 18 years of age.

Uses of Butodol Injection 1 ml

Treatment of Pain relief.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Butodol Injection 1 ml contains 'Butorphanol', an opioid analgesic that helps relieve moderate to severe pain post-surgery, muscle pain and migraine headaches. Butodol Injection 1 ml is also used as a part of anaesthesia during surgery and early labor. It helps relieve pain in various conditions like toothache, rheumatoid arthritis, and osteoarthritis. It works by acting on the opioid receptors and blocking the transmission of pain signals.

How Butodol Injection 1 ml Works

Butodol Injection 1 ml contains 'Butorphanol' which works by blocking the transmission of pain signals located in the brain that controls pain, pleasure, and addictive behaviors. Butorphanol also acts as a pre-anaesthetic during surgery, antitussive (cough suppressant), and antiemetic (prevents vomiting) medication.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Butodol Injection 1 ml

  • Constipation 
  • Nausea
  • Vomiting 
  • Dizziness
  • Drowsiness
  • Headache

What if I have taken an overdose of Butodol Injection 1 ml

Since Butodol Injection 1 ml is administered by a healthcare professional, an overdose is unlikely to occur. However, seek immediate medical attention if you experience symptoms of overdose such as a change in consciousness, extremely shallow or slow breathing, irregular heartbeats, loss of consciousness, shortness of breath, and swelling in hands and feet.

Drug Warnings

Inform your doctor if you have a history of liver, kidney or heart diseases, abdominal problems (gallbladder disease, pancreatitis), adrenal gland diseases (Addison's disease), brain disorders (fits, tumours, increased intracranial pressure), heart problems (irregular heartbeat, chest pain, a recent history of heart attack), high blood pressure and breathing problems (asthma, chronic obstructive pulmonary disease-COPD, sleep apnoea) before starting Butodol Injection 1 ml. If you have any mood disorders (toxic psychosis), spine problems (kyphoscoliosis), gastrointestinal problems (diarrhoea, paralytic ileus), personal or a family history of a substance use disorder like overuse of or addiction to drugs or alcohol, urination problems (enlarged prostate or urethral stricture) and an underactive thyroid (hypothyroidism), inform your doctor in advance before starting Butodol Injection 1 ml. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother. Butodol Injection 1 ml causes dizziness and drowsiness, so do not drive until you are mentally alert. Avoid alcohol to prevent the worsening of side effects further. Butodol Injection 1 ml is not recommended for anyone below 18 years of age.

Drug-Drug Interactions

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ButorphanolChlordiazepoxide
Severe
ButorphanolHydroxyzine
Severe

Drug-Drug Interactions

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ButorphanolChlordiazepoxide
Severe
How does the drug interact with Butodol Injection 1 ml:
Co-administration of Butodol Injection 1 ml with chlordiazepoxide can increase the risk of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Butodol Injection 1 ml and chlordiazepoxide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, shortness of breath, palpitations, numbness in hands and feet, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ButorphanolHydroxyzine
Severe
How does the drug interact with Butodol Injection 1 ml:
Using Hydroxyzine together with Butodol Injection 1 ml can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
There may be a possibility of interaction between Hydroxyzine and Butodol Injection 1 ml, but it can be taken if prescribed by a doctor. Since these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgment, response speed, and motor coordination, you should avoid driving or operating dangerous machinery until you know how they affect you. Do not discontinue any medications without consulting a doctor.
ButorphanolZiprasidone
Severe
How does the drug interact with Butodol Injection 1 ml:
Co-administration of Butodol Injection 1 ml with Ziprasidone can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Ziprasidone and Butodol Injection 1 ml, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling tired, dizzy, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
ButorphanolTramadol
Severe
How does the drug interact with Butodol Injection 1 ml:
Co-administration of Butodol Injection 1 ml with tramadol may increase the risk and severity of the seizure.

How to manage the interaction:
Taking Butodol Injection 1 ml with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ButorphanolPhenytoin
Severe
How does the drug interact with Butodol Injection 1 ml:
Coadministration of Phenytoin and Butodol Injection 1 ml may decrease the blood levels of Butodol Injection 1 ml, which could lower the action of Butodol Injection 1 ml.

How to manage the interaction:
Although taking Phenytoin and Butodol Injection 1 ml together can result in an interaction, it can be taken if your doctor has prescribed it. Do not exceed the doses or frequency and duration of use prescribed by a doctor. Avoid driving or operating hazardous machinery.
ButorphanolNevirapine
Severe
How does the drug interact with Butodol Injection 1 ml:
When Butodol Injection 1 ml is taken with Nevirapine may reduce the blood levels of Butodol Injection 1 ml. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Nevirapine and Butodol Injection 1 ml together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience watery eyes, runny nose, sneezing, yawning, excessive sweating, goose bumps, fever, chills, flushing, restlessness, irritability, anxiety, depression, pupil dilation, tremor, rapid heartbeat, body aches, involuntary twitching and kicking, abdominal cramping, loss of appetite, nausea, vomiting, diarrhea, and weight loss call a doctor right away. Do not discontinue any medications without consulting a doctor.
ButorphanolAripiprazole
Severe
How does the drug interact with Butodol Injection 1 ml:
Using Aripiprazole together with Butodol Injection 1 ml can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Aripiprazole with Butodol Injection 1 ml together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend other options that won't cause any problems. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
ButorphanolKetoconazole
Severe
How does the drug interact with Butodol Injection 1 ml:
Coadministration of Ketoconazole and Butodol Injection 1 ml may increase the blood levels of Butodol Injection 1 ml. This may increase side effects (drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment).

How to manage the interaction:
Although taking Ketoconazole and Butodol Injection 1 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you develop dizziness, fainting, confusion, excessive sleepiness, a slow heartbeat, shallow breathing, you should consult a doctor. Do not discontinue any medication without consulting a doctor.
ButorphanolCiprofloxacin
Severe
How does the drug interact with Butodol Injection 1 ml:
Taking Butodol Injection 1 ml with ciprofloxacin may increase the blood levels of Butodol Injection 1 ml, which may increase the risk of side effects.

How to manage the interaction:
Although taking ciprofloxacin and Butodol Injection 1 ml together can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience drowsiness, dizziness, lightheadedness, slow heartbeat, shallow or difficult breathing, difficulty concentrating, and impairment in thinking. Do not discontinue any medications without consulting a doctor. Avoid activities requiring mental concentration such as driving or operating dangerous machinery, and be cautious when getting up from a sitting or lying position.
ButorphanolBaclofen
Severe
How does the drug interact with Butodol Injection 1 ml:
Co-administration of Baclofen with Butodol Injection 1 ml can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Baclofen and Butodol Injection 1 ml, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like dizziness, shortness of breath, palpitations, or chest discomfort, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

Yes

Therapeutic Class

OPIOID ANALGESIC AND ANESTHESIA ADJUNCT

Butodol Injection 1 ml Substitute

Substitutes safety advice
  • Butrum 1mg Injection 1ml

    by AYUR

    35.10per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Butodol Injection 1 ml. Alcohol intake, along with Butodol Injection 1 ml, may cause increased drowsiness and dizziness.

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Pregnancy

Caution

Please consult your doctor before taking Butodol Injection 1 ml if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Butodol Injection 1 ml is excreted into the breast milk. Please consult your doctor before taking Butodol Injection 1 ml if you are a nursing mother.

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Driving

Unsafe

Butodol Injection 1 ml may make you feel dizzy and drowsy. Do not drive or operate machinery if you experience these side effects.

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Liver

Caution

Please consult your doctor since Butodol Injection 1 ml should be used with caution in patients with liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor since Butodol Injection 1 ml should be used with caution in patients with kidney impairment/kidney disease.

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Children

Unsafe

Butodol Injection 1 ml is not recommended in anyone below 18 years of age.

FAQs

Butodol Injection 1 ml is used to treat moderate to severe pain post-surgery, muscle pain, and migraine-related headaches. It is also used as an anaesthesia adjunct during surgery and early labour.
Butodol Injection 1 ml contains 'Butorphanol', an opioid pain reliever that blocks the transmission of pain signals by acting on specific centres of the brain. Thus Butodol Injection 1 ml reduces pain associated with various conditions like surgery pain, muscle pain, migraine headaches, arthritis pain and toothache.
Butodol Injection 1 ml may cause your blood pressure to drop upon administration of nasal spray. This may lead to fainting, light-headedness and dizziness after its use in the first hour. To prevent this from happening, remain sitting or lying down after using Butodol Injection 1 ml.
It is not recommended to suddenly stop taking Butodol Injection 1 ml since it may produce withdrawal symptoms, especially when you used Butodol Injection 1 ml for a longer time or in high doses. Please seek medical advice on how to stop taking Butodol Injection 1 ml safely. Your doctor may lower your dose slowly to prevent withdrawal symptoms.
Butodol Injection 1 ml can cause side effects like dizziness and drowsiness, hence it is advised to remain sitting or lying after taking Butodol Injection 1 ml. You are also advised not to drive or operate machinery until you are mentally alert.
Butodol Injection 1 ml may sometimes cause addiction despite its medical benefits. The risk of habit-forming or addiction is higher in people with a history of substance use disorder like overuse of drugs and alcohol. It is strictly recommended to use Butodol Injection 1 ml in the dose and duration prescribed by your doctor. Do not double the dose.
If you have liver or kidney issues, you should use Butodol Injection 1 ml with caution as it is primarily excreted through the kidneys, and its use may pose a higher risk of side effects in patients with impaired kidney function. Butodol Injection 1 ml is also extensively metabolized in the liver. Always consult your doctor before using Butodol Injection 1 ml if you have liver or kidney problems.
If you suddenly stop using Butodol Injection 1 ml, you may experience withdrawal symptoms such as nausea, vomiting, fatigue, dizziness, drowsiness, irritability, insomnia or runny nose. It is important to consult your doctor before discontinuing Butodol Injection 1 ml, as they can provide guidance on safely minimizing withdrawal effects.
While on therapy with Butodol Injection 1 ml, be cautious if you experience drowsiness and dizziness, or if you have breathing problems, and avoid driving or operating heavy machinery. Be aware of the potential for dependence or withdrawal symptoms with prolonged use of Butodol Injection 1 ml. Inform your doctor if you have a history of liver, kidney or heart diseases, abdominal problems (gallbladder disease, pancreatitis), adrenal gland diseases (Addison's disease), brain disorders (fits, tumours, increased intracranial pressure), heart problems (irregular heartbeat, chest pain, a recent history of heart attack), high blood pressure and breathing problems (asthma, chronic obstructive pulmonary disease-COPD, sleep apnoea) before starting Butodol Injection 1 ml.
Butodol Injection 1 ml causes side effects such as constipation, nausea, vomiting, dizziness, drowsiness, and headache. These do not require any medical attention as they will gradually reduce over time. Please, contact a doctor if these persist longer

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - BUT0007

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