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  3. Bupro XL 300 mg Tablet 10's

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Bupro XL 300 mg Tablet is used to treat depression. Besides this, it is also used to help people stop smoking. It contains Bupropion which works by increasing the levels of serotonin responsible for improving mood. In some cases, this medicine may cause side effects such as nausea, headache, dizziness, vomiting, difficulty sleeping, fever, constipation, and sweating. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Bupro XL 300 mg Tablet 10's, Pack of 10 TABLETS
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Synonym :

BUPROPION HYDROCHLORIDE

Composition :

BUPROPION-300MG

Manufacturer/Marketer :

D D Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Bupro XL 300 mg Tablet

Bupro XL 300 mg Tablet is used in the treatment of depression. It’s also used to help people stop smoking. Depression is a mood disorder that affects day to day life of a person. A person may have symptoms such as feeling sad or feeling lost and might have mood swings. 

Bupro XL 300 mg Tablet contains Bupropion, which is used to treat depression. It works by increasing the level of a chemical messenger (serotonin) in the brain responsible for improving mood and physical symptoms of depression. Hence, it helps to improve mood. 

Take Bupro XL 300 mg Tablet as prescribed by your doctor. You are advised to take Bupro XL 300 mg Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience certain common side effects, such as nausea, headache, dizziness, vomiting, insomnia (difficulty in sleeping), fever, constipation, sweating, allergic reaction, impaired concentration, and dry mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to consult your doctor if you experience these side effects persistently. 

Do not take Bupro XL 300 mg Tablet if you are allergic to Bupro XL 300 mg Tablet or its ingredients. Tell your doctor if you are taking antidepressants, antipsychotic medication, or antihypertensives, especially if you are taking an MAO inhibitor (medicine to treat depression). Try not to stop taking Bupro XL 300 mg Tablet of your own, as it may lead to unpleasant side effects. Let your doctor know about this, as it may cause withdrawal symptoms. Bupro XL 300 mg Tablet is used with caution in children and adolescents under 18 years of age as it increases suicidal tendencies in this population. It is also habit-forming, so always take it in the dose and duration prescribed by a doctor, and never self-medicate.

Uses of Bupro XL 300 mg Tablet

Treatment of Depression, Smoking addiction.

Directions for Use

Take Bupro XL 300 mg Tablet with or without food or as directed by your physician. Swallow the whole tablet with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Bupro XL 300 mg Tablet belongs to a class of drugs known as 'antidepressant', which contains Bupropion primarily used in treating depression. In addition to this, it is also used by people who are addicted to smoking. It works by increasing serotonin levels. Serotonin is a chemical messenger in the brain responsible for improving mood and physical symptoms of depression. Hence, it helps to improve mood. 

How Bupro XL 300 mg Tablet Works

Bupro XL 300 mg Tablet contains Bupropion, which is used to treat depression. It works by increasing the level of a chemical messenger (serotonin) in the brain responsible for improving mood and physical symptoms of depression. Hence, it helps to improve mood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bupro XL 300 mg Tablet

  • Nausea
  • Headache
  • Dizziness
  • Vomiting
  • Insomnia (difficulty in sleeping)
  • Tremors, feeling anxious or nervous
  • Fever
  • Weight loss
  • Muscle pain
  • Constipation
  • Sweating
  • Allergic reaction
  • Impaired concentration
  • Dryness in mouth

What if I have taken an overdose of Bupro XL 300 mg Tablet

Take Bupro XL 300 mg Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include seizures, loss of consciousness, rapid/pounding heartbeat, and hallucinations. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Bupro XL 300 mg Tablet if you are allergic to Bupro XL 300 mg Tablet or its ingredients. Tell your doctor if you are taking antidepressants, antipsychotic medication, or antihypertensives, especially if you are taking MAO inhibitors (medicine to treat depression). Patients with liver diseases, diabetes, heart disease and bleeding disorders should use Bupro XL 300 mg Tablet with caution. Please do not stop the treatment abruptly, as it can cause withdrawal reactions. Bupro XL 300 mg Tablet may cause suicidal thoughts and worsen anxiety. Bupro XL 300 mg Tablet is used with caution in children and adolescents under 18 years of age as it increases suicidal tendencies in this population. It is also habit-forming, so always take it in the dose and duration prescribed by a doctor, and never self-medicate.

Drug-Drug Interactions

verifiedApollotooltip
BupropionMetoclopramide
Critical
BupropionIsocarboxazid
Critical

Drug-Drug Interactions

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BupropionMetoclopramide
Critical
How does the drug interact with Bupro XL 300 mg Tablet 10's:
Co-administration of Metoclopramide with Bupro XL 300 mg Tablet 10's can increase the levels of Metoclopramide and increase the risk or severity of developing seizures (fits).

How to manage the interaction:
Taking Metoclopramide with Bupro XL 300 mg Tablet 10's is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
BupropionIsocarboxazid
Critical
How does the drug interact with Bupro XL 300 mg Tablet 10's:
Using Bupro XL 300 mg Tablet 10's together with isocarboxazid can cause blood pressure to get dangerously high.

How to manage the interaction:
Taking Isocarboxazid with Bupro XL 300 mg Tablet 10's can cause an interaction, consult a doctor before taking it. Consult a doctor if you experience headache, sleep disturbances, tremor, restlessness, nervousness, anxiety, palpitation, and rapid heartbeat. Do not stop using any medications without talking to a doctor.
BupropionRasagiline
Critical
How does the drug interact with Bupro XL 300 mg Tablet 10's:
Taking Rasagiline with Bupro XL 300 mg Tablet 10's can cause increased blood pressure.

How to manage the interaction:
Taking rasagiline with Bupro XL 300 mg Tablet 10's is not recommended as it can result in an interaction but can be taken if a doctor has advised it. However, if you experience headache, sleep disturbances, tremor (shaking of hands & legs), restlessness, nervousness, anxiety, and rapid heartbeat contact a doctor. Do not discontinue any medications without consulting a doctor.
BupropionTranylcypromine
Critical
How does the drug interact with Bupro XL 300 mg Tablet 10's:
Taking tranylcypromine with Bupro XL 300 mg Tablet 10's can increase the risk of severe high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Bupro XL 300 mg Tablet 10's can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, sleep disturbances, tremor (shaking of hands & legs), restlessness, nervousness, anxiety, palpitation, and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
BupropionSafinamide
Critical
How does the drug interact with Bupro XL 300 mg Tablet 10's:
Taking Safinamide with Bupro XL 300 mg Tablet 10's can increase the risk of high blood pressure.

How to manage the interaction:
Taking Safinamide with Bupro XL 300 mg Tablet 10's is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately If you experience symptoms such as headache, sleep disturbances, tremor (shaking of hands & legs), restlessness, nervousness, anxiety, palpitation, and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
BupropionSertraline
Severe
How does the drug interact with Bupro XL 300 mg Tablet 10's:
Taking Bupro XL 300 mg Tablet 10's with Sertraline may raise the chance of seizures(fits). Furthermore, Bupro XL 300 mg Tablet 10's can raise sertraline levels in the blood.

How to manage the interaction:
Co-administration of Bupro XL 300 mg Tablet 10's along with Sertraline can lead to an interaction, it can be taken if a doctor has prescribed it. Avoid driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
BupropionNorfloxacin
Severe
How does the drug interact with Bupro XL 300 mg Tablet 10's:
Coadministration of Bupro XL 300 mg Tablet 10's with norfloxacin may enhance the risk or severity seizure (fits).

How to manage the interaction:
Co-administration of Bupro XL 300 mg Tablet 10's along with norfloxacin can lead to an interaction, it can be taken if recommended by a doctor. While taking these medications, you should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
BupropionClozapine
Severe
How does the drug interact with Bupro XL 300 mg Tablet 10's:
Taking Bupro XL 300 mg Tablet 10's with clozapine may raise clozapine levels in the blood which increases risk of seizures(fits).

How to manage the interaction:
Co-administration of Bupro XL 300 mg Tablet 10's along with clozapine can lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
BupropionPhenylpropanolamine
Severe
How does the drug interact with Bupro XL 300 mg Tablet 10's:
Bupro XL 300 mg Tablet 10's is capable of causing seizures (fits), and combining it with phenylpropanolamine, may enhance the risk.

How to manage the interaction:
Co-administration of Bupro XL 300 mg Tablet 10's along with phenylpropanolamine can lead to an interaction, it can be taken if recommended by a doctor. While taking these medications, you should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
BupropionCiprofloxacin
Severe
How does the drug interact with Bupro XL 300 mg Tablet 10's:
Taking ciprofloxacin with Bupro XL 300 mg Tablet 10's can increase the risk of seizures(fits).

How to manage the interaction:
Co-administration of Bupro XL 300 mg Tablet 10's along with ciprofloxacin can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience any unusual symptoms, consult a doctor. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise, which can help lower anxiety by releasing endorphins and improving your sleep.

  • Find humour in your daily life. Try to watch light-hearted shows to help relieve stress.

  • You can try increasing your mindfulness by including yoga, meditation, cognitive therapy and mindfulness-based stress reduction.

  • Drink enough water to stay hydrated and limit consumption of alcohol and caffeine to relieve anxiety.

  • Include a diet rich in whole grains, vegetables and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.

  • Herbs like turmeric, ginger and chamomile contain anti-inflammatory properties. Including these stuff in meals can reduce inflammation caused due to anxiety disorder.

  • Reduce your alcohol, caffeine, added sugar, high salt and fat intake. Especially transfat may help also help reduce inflammation.

  • You should include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea and lemon balm.

  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

Yes

Therapeutic Class

ANTIDEPRESSANT

Bupro XL 300 mg Tablet Substitute

Substitutes safety advice

  • Bupron XL 300 Tablet 10's

    ₹32.58per tablet

  • Buletrip SR-300 Tablet 10's

    ₹24.30per tablet

  • Bupet Xl 300mg Tablet 10's

    by AYUR

    ₹23.58per tablet

  • Atydep-SR 300 Tablet 10's

    ₹23.00per tablet

  • Unidep SR 300 Tablet

    ₹19.80per tablet

Product Substitutes

Info icon

Bupron XL 300 Tablet 10's

₹325.8

MRP ₹362

Info icon

Buletrip SR-300 Tablet 10's

₹243

MRP ₹270

Info icon

Bupet Xl 300mg Tablet 10's

₹235.8

MRP ₹262

Info icon

Atydep-SR 300 Tablet 10's

₹230

Info icon

Unidep SR 300 Tablet

₹198

MRP ₹220

Info icon

Atydep 300mg Tablet SR

₹160.2

MRP ₹178

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Bupro XL 300 mg Tablet as it may cause serious side effects.

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Pregnancy

Unsafe

Bupro XL 300 mg Tablet is a pregnancy category B drug. If you already take this medicine before becoming pregnant, consult your doctor immedietly. It can pose a small risk of problems for an unborn baby. Your doctor might prescribe this medicine during pregnancy if the benefits outweigh the risks.

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Breast Feeding

Unsafe

In very small quantities, Bupro XL 300 mg Tablet enters the breast milk and may have negative effects on breastfed babies. If the infant is in good health, it may be prescribed. Please see your doctor, though, if the baby stops eating as well as usual after taking Bupro XL 300 mg Tablet or starts sleeping a lot more than usual.

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Driving

Unsafe

Do not drive after taking Bupro XL 300 mg Tablet as it may cause drowsiness and interfere with your driving ability.

bannner image

Liver

Caution

Bupro XL 300 mg Tablet to be taken with caution, especially if you have a history of liver diseases. Your doctor may adjust the dose if required based on your condition.

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Kidney

Caution

Bupro XL 300 mg Tablet to be taken with caution, especially if you have a history of kidney disease. Your doctor may adjust the dose if required based on your condition.

bannner image

Children

Unsafe

Bupro XL 300 mg Tablet is not recommended for use in children below 18 years. Its safety and efficacy are not established in children.

FAQs

Bupro XL 300 mg Tablet is used in the treatment of depression. It is also used to help people stop smoking.
Bupro XL 300 mg Tablet contains Bupropion, primarily used in treating depression. In addition to this, it is also used by people who are addicted to smoking. It works by increasing serotonin levels. Serotonin is a chemical messenger in the brain responsible for improving mood and physical symptoms of depression. Hence, it helps to improve mood.
Certain side-effects of Bupro XL 300 mg Tablet can be dealt with simple tips such as if you experience dry mouth, you can chew sugar-free gum or take sugar-free sweets. If you are sweating a lot while taking Bupro XL 300 mg Tablet , wear loose clothing and use a strong antiperspirant. If you cannot sleep after taking Bupro XL 300 mg Tablet , prefer to take it in the morning to avoid sleep disturbances. If you feel sleepy after taking Bupro XL 300 mg Tablet , avoid taking it in the evening and limit your alcohol intake. If you feel tired or weak after taking Bupro XL 300 mg Tablet , sit or lie down until you feel better. If you feel that the side effects are worsening, please consult your doctor.
Yes, however, there may be an increased risk of experiencing suicidal tendencies in children, adolescents and young adults. This medicine is not recommended for children less than 18 years of age.
Taking Bupro XL 300 mg Tablet in more than the recommended dose can cause unpleasant side effects such as dizziness, tremor, agitation, convulsion, coma, nausea, vomiting, changes in heart rhythm, decreased blood pressure and change in body fluid/salt balance.
In elderly patients, the risk of side effects is more if you are taking Bupro XL 300 mg Tablet . For the patients who are elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.
Bupro XL 300 mg Tablet is not advised in cases if you are allergic to Bupro XL 300 mg Tablet , have epilepsy (seizure disorder or fits), diabetes, sexual disorders, liver or kidney disease, any heart problems, bleeding or clotting disorders, or currently taking medicines for depression known as MAO inhibitors (such as Isocarboxazid, Phenelzine, Selegiline) or problems with alcohol or other prescription drugs. It should not be given to a person having a low heart rate along with symptoms of diarrhoea and vomiting, pregnant women, trying to get pregnant, breastfeeding, or having eye problems such as glaucoma. In diabetics, it can cause difficulty in keeping stable blood sugar levels.
No, Bupro XL 300 mg Tablet does not help with anxiety and sleeplessness. It is used to treat depression.
Though Bupropion may have a low risk of addiction, Bupro XL 300 mg Tablet does not cause addiction if taken in the dose and duration prescribed by the doctor.
Factors that can increase the chances of seizures with Bupro XL 300 mg Tablet are sudden and large increments in dose, bulimia or anorexia nervosa (eating disorder), history of head trauma or prior seizure, central nervous system (CNS) tumour, the presence of severe hepatic cirrhosis, and concomitant medications that lower the seizure threshold.
It is very rare to develop eye problems like redness, pain, and blurred vision with Bupro XL 300 mg Tablet . Please consult the doctor if you experience any eye problems during treatment with Bupro XL 300 mg Tablet .
Avoid exceeding the prescribed dose and use Bupro XL 300 mg Tablet cautiously with medicines that might lower the seizure threshold such as antipsychotics, antidepressants, theophylline, and systemic steroids.
Bupro XL 300 mg Tablet may cause high blood pressure, therefore, let the doctor know if you have hypertension or if you are taking medicines used to treat high blood pressure.
Bupro XL 300 mg Tablet may cause side effects such as nausea, headache, dizziness, vomiting, insomnia (difficulty in sleeping), fever, constipation, sweating, allergic reaction, impaired concentration, and dry mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to consult your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

1/583,585,586 Sitapura Industrial Area, RIICO, Tonk Road, Jaipur
Other Info - BUP0049

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Author Details

Doctor imageDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.drugs.com/bupropion.html#:~:text=Bupropion%20is%20an%20antidepressant%20medication,listed%20in%20this%20medication%20guide.
  2. https://medlineplus.gov/druginfo/meds/a695033.html
  3. https://www.medicines.org.uk/emc/files/pil.3827.pdf
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