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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:48 PM IST
BUPRIGESIC INJECTION is used to treat opioid dependence (addiction to opioid drugs). It contains Buprenorphine which prevents withdrawal symptoms in patients who stop receiving opioid drugs by producing similar effects to these drugs. It may also provide pain relief by acting on specific receptors in the brain. This medicine may sometimes cause side effects such as dry mouth, vomiting, blurred vision, constipation, dizziness, tiredness and injection site reactions. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

BUPRENORPHINE-0.3MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About BUPRIGESIC INJECTION

BUPRIGESIC INJECTION belongs to a class of drugs called 'opioid analgesic' primarily used to treat opioid addiction (narcotics) like morphine, heroin, etc. In some cases, it is also used to treat, prevent and treat moderate to severe pain. Drug addiction, also called substance use disorder, is a disease that affects a person's brain and behaviour and leads to an inability to control the use of a legal or illegal drug or medication.

BUPRIGESIC INJECTION contains 'Buprenorphine', an opioid partial agonist-antagonists that prevent withdrawal symptoms in patients who stop receiving opioid drugs by producing similar effects to these drugs. It has been approved for the treatment of narcotic-use disorders. A combination of buprenorphine and naloxone is prescribed for use in the treatment of opioid dependence. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

BUPRIGESIC INJECTION will be administered by a trained healthcare professional. Hence, do not self-administer. This medicine may cause certain side effects such as dry mouth, vomiting, blurred vision, constipation, dizziness, tiredness and injection site reactions. Most of these side effects of BUPRIGESIC INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

BUPRIGESIC INJECTION should be avoided if you are allergic to it. Do not use BUPRIGESIC INJECTION if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. This medicine is not recommended for children below 18 years of age. BUPRIGESIC INJECTION is a habit-forming drug, and there is a risk of dependence on BUPRIGESIC INJECTION. Hence, do not stop receiving BUPRIGESIC INJECTION without consulting a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors or general unwell feeling. BUPRIGESIC INJECTION may decrease fertility in men and women. Do not consume alcohol with BUPRIGESIC INJECTION as it may increase the risk of side effects. Inform your doctor if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease before starting treatment with BUPRIGESIC INJECTION.

Uses of BUPRIGESIC INJECTION

Treatment of Opioid (drug) addiction, Pain.

Medicinal Benefits

The BUPRIGESIC INJECTION contains Buprenorphine as a substitution (replacement) treatment in patients addicted to opioid drugs (heroin and morphine, etc.). It prevents or reduces the unpleasant withdrawal symptoms experienced when addicts stop using opioid drugs. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain. Compared to other opioid analgesics like methadone, BUPRIGESIC INJECTION has the advantage of having less sedation (sleepiness), decreased respiratory depression, decreased risk of diversion, fewer withdrawal symptoms and lower risk of toxicity at higher doses. 

Side Effects of BUPRIGESIC INJECTION

  • Weakness
  • Nervousness
  • Dizziness
  • Headache
  • Orthostatic hypotension (a sudden dip of blood pressure on standing)
  • Constipation
  • Diarrhea
  • Nausea
  • Vomiting
  • Sweating
  • Injection site reactions

Directions for Use

BUPRIGESIC INJECTION will be administered by a trained healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Please do not stop receiving BUPRIGESIC INJECTION suddenly, as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to BUPRIGESIC INJECTION or any other medicines, please tell your doctor.  Do not use BUPRIGESIC INJECTION if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. BUPRIGESIC INJECTION is not recommended for children below 18 years of age.  Avoid consuming alcohol with BUPRIGESIC INJECTION as it may increase the risk of side effects. Do not use this medicine if you have used an MAO inhibitor (antidepressants) in the past 14 days, as a dangerous drug interaction could occur. BUPRIGESIC INJECTION should be used with extreme caution in patients who have a history of alcoholism or drug abuse. Inform your doctor if you have severe breathing problems, asthma, delirium tremens (confusion and shaking after stopping drinking alcohol), hallucinations (seeing and hearing things that are not there), kidney or liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression or other conditions that are treated with antidepressants. 

Therapeutic Class

OPIOID ANTAGONISTS

Diet & Lifestyle Advise

  • Do regular exercise such as swimming or walking.
  • Drink plenty of water while on treatment with BUPRIGESIC INJECTION to avoid dry mouth.
  • Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while receiving BUPRIGESIC INJECTION.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

Yes

How BUPRIGESIC INJECTION Works

BUPRIGESIC INJECTION contains 'Buprenorphine', an opioid partial agonist-antagonists that prevent withdrawal symptoms in patients who stop receiving opioid drugs by producing similar effects to these drugs. It has been approved for the treatment of narcotic-use disorders. A combination of buprenorphine and naloxone is prescribed for use in the treatment of opioid dependence. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

What if I have taken an overdose of BUPRIGESIC INJECTION

Overdose of BUPRIGESIC INJECTION may cause narrowing or widening of the pupils (black circles in the centre of the eye), slowed/shallow/difficulty breathing, extreme sleepiness or drowsiness, unable to respond or wake up, coma (loss of consciousness for a period of time), and slow heartbeat. Since BUPRIGESIC INJECTION is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any of these symptoms.
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Alcohol

Unsafe

BUPRIGESIC INJECTION may cause dizziness, drowsiness, blurred vision, or impaired thinking in some people. Alcohol consumption may even worsen these effects. Hence, do not consume alcohol while on treatment with this medicine.

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Pregnancy

Unsafe

BUPRIGESIC INJECTION is not recommended during pregnancy as it may cause life-threatening withdrawal symptoms in the newborn. Hence, inform your doctor before administering BUPRIGESIC INJECTION if you are pregnant or planning pregnancy. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It may be unsafe to use during breastfeeding as it passes into breastmilk and may cause sleepiness and decreased heart rate in your infant. It is not recommended for use in breastfeeding. Hence, if you are breastfeeding, inform your doctor before receiving BUPRIGESIC INJECTION. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

BUPRIGESIC INJECTION may cause dizziness, blurred vision or drowsiness in some people. It is an offence to drive if BUPRIGESIC INJECTION affects you. Therefore, avoid driving if you feel drowsy, dizzy or experience vision problems after administration of BUPRIGESIC INJECTION.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving BUPRIGESIC INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving BUPRIGESIC INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

BUPRIGESIC INJECTION is not recommended for use in children below 18 years of age as the safety and effectiveness have not been established.

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - BUP0003

Author Details

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FAQs

BUPRIGESIC INJECTION is used to treat opioid addiction.
BUPRIGESIC INJECTION consists of Buprenorphine is an opioid partial agonist. It prevents withdrawal symptoms in patients who stop receiving opioid drugs by producing similar effects to these drugs. It also provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.
Yes, BUPRIGESIC INJECTION may cause withdrawal symptoms such as sweating, feeling hot and cold, runny eyes and nose, feeling or being sick, diarrhoea, stomach cramps, poor sleep, and just feeling awful. Therefore, if you experience any difficulty while receiving BUPRIGESIC INJECTION, do not stop administration suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.
Chronic use of opioids may cause reduced fertility (ability to have children) in females and males of reproductive potential. It is not known whether these effects on fertility are reversible. However, it is essential to talk to your doctor before starting treatment with BUPRIGESIC INJECTION if you think you may want to have a baby in the future.
No, you are not recommended to use BUPRIGESIC INJECTION with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with BUPRIGESIC INJECTION may cause life-threatening respiratory depression and death have occurred. However, please consult a doctor before receiving BUPRIGESIC INJECTION with other medicines.
Yes, BUPRIGESIC INJECTION may cause addiction, especially if used for a prolonged time. Therefore, BUPRIGESIC INJECTION should be given only for a short duration under strict medical supervision, particularly to patients susceptible to drug abuse. BUPRIGESIC INJECTION should be administered only as advised by a doctor as overuse, or misuse of BUPRIGESIC INJECTION can lead to overdose or death.

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