Brufen 400 Tablet is used to relieve mild to moderate pain, inflammation, and fever in adults and paediatrics above 6 months of age. It helps to treat conditions such as menstrual cramps, headache, neuralgia (nerve-related pain), migraine, back pain, dental pain, swelling and stiffness in joints and muscles, cold, and flu symptoms.
 
Brufen 400 Tablet contains 'Ibuprofen', which works by blocking the effect of a chemical messenger in the body. It is known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, fewer prostaglandins are produced, which reduces mild to moderate pain, inflammation, and fever. 
 
Take Brufen 400 Tablet as prescribed by your doctor. You are advised to take Brufen 400 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as indigestion, diarrhoea, constipation, flatulence (gas), general weakness, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 
 
Brufen 400 Tablet may increase the chances of stomach ulcers, bleeding and the risk of heart attack or stroke. Avoid or limit the intake of alcohol while taking Brufen 400 Tablet . Consult your doctor before taking Brufen 400 Tablet if you are pregnant or breastfeeding; your doctor will prescribe Brufen 400 Tablet only if the benefits outweigh the risks. Brufen 400 Tablet may cause drowsiness, so drive with caution. Do not take Brufen 400 Tablet for more than 10 days unless prescribed by your doctor. If your condition does not improve even after taking Brufen 400 Tablet for 10 days, please consult your doctor.

Brufen 400 Tablet belongs to the group of NSAIDs used to relieve pain and inflammation. Brufen 400 Tablet relieves period pain, headache, neuralgia (nerve-related pain), migraine, back pain, dental pain, swelling and stiffness in joints and muscles, cold, flu, and fever symptoms. Brufen 400 Tablet works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Besides this, it also minimizes fever due to pain and inflammatory conditions.

• Indigestion
• Diarrhoea
• Constipation
• Flatulence (gas)
• Nausea
• Rash
• Weakness
• Dizziness

If you have had any recent heart bypass surgery (CABG), do not use Brufen 400 Tablet . Brufen 400 Tablet increases the chances of stomach ulcers and bleeding, so do not exceed the dose and duration prescribed by your doctor. Consult your doctor before taking Brufen 400 Tablet if you are pregnant or breastfeeding; your doctor will prescribe you Brufen 400 Tablet only if the benefits outweigh the risks. Brufen 400 Tablet may cause drowsiness, so drive with caution. Do not take Brufen 400 Tablet for more than 10 days unless prescribed by your doctor. If your condition does not improve even after taking Brufen 400 Tablet for 10 days, please consult your doctor. Avoid consuming alcohol with Brufen 400 Tablet as it could lead to increased drowsiness and increase the risk of stomach bleeding. Stop taking Brufen 400 Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take aspirin or any other NSAIDs for pain relief along with Brufen 400 Tablet unless prescribed by the doctor.

Drug-Drug Interactions: Brufen 400 Tablet may have interaction with pain killers (naproxen, aspirin), anti-depressants (duloxetine, sertraline, escitalopram, fluoxetine), and drugs used to treat arthritis (meloxicam).

Drug-Food Interactions: Avoid consuming alcohol along with Brufen 400 Tablet as it could lead to increased drowsiness and dizziness. It could also increase the risk of stomach bleeding.

Drug-Disease Interactions: Inform your doctor if you have/had stomach/intestine ulcer or bleeding, heart failure, fluid retention (oedema), asthma, high blood pressure, hyperkalemia (high levels of potassium), thrombosis (formation of clots), anaemia (low red blood cells), rash, platelet aggregation inhibition, kidney and liver problems.

• ASPIRIN
• NAPROXEN
• DULOXETINE
• SERTRALINE
• ESCITALOPRAM
• MELOXICAM
• FLUOXETINE

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.

• Performing yoga may also help in improving joint flexibility and pain management.

• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

• Follow heat or cold therapy. Apply a cold or hot compress on the joints for 15-20 minutes regularly.

• De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.

• Acupuncture, massage, and physical therapy may also be helpful.

• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

• Avoid alcohol consumption.

Pain: It is not a disease but a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis, and certain medical conditions.