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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:37 PM IST
Bro-Zedex Syrup is a combination medicine which belongs to the class of expectorants. It is used in the treatment of wet/productive cough. This medicine works by increasing the volume of fluid in the airways, reducing the stickiness of mucus, and removing it from the airways. Common side effects include nausea, diarrhoea, vomiting, stomach discomfort, sweating, muscle cramps, dizziness, and headache.
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Manufacturer/Marketer

Wockhardt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Bro-Zedex Syrup

Bro-Zedex Syrup is used to treat cough associated with vicious and excessive mucus in patients with asthma and COPD (chronic obstructive pulmonary disorder). Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) produces mucous or sputum. 

Bro-Zedex Syrup contains Guaifenesin, Bromhexine hydrochloride, Terbutaline sulphate and Menthol. Guaifenesin works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus. Bromhexine hydrochloride works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose, making it easier to cough it out. Terbutaline sulphate relaxes muscles and widens the airways making breathing easier. Menthol produces a cooling sensation and provides relief from minor throat irritation due to cough deposition.

Your doctor will recommend the dose and duration of Bro-Zedex Syrup based on your medical condition. Some people may experience common side effects such as diarrhoea, nausea, vomiting, drowsiness, headache, dizziness, skin rash, tremor, stomach upset and fast heartbeats. Most of these side effects of Bro-Zedex Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Consult your doctor if you are pregnant or planning for pregnancy. Avoid taking Bro-Zedex Syrup while breastfeeding as it is excreted in breast milk and may cause adverse effects in the baby. Bro-Zedex Syrup may cause dizziness, so drive or operate machinery only if you are alert. Bro-Zedex Syrup should be used with caution in children, especially those below 2 years of age, if prescribed by a doctor. Keep your doctor informed about your health condition and medication to rule out any interactions.

Uses of Bro-Zedex Syrup

Treatment of Cough

Medicinal Benefits

Bro-Zedex Syrup is a combination of four drugs, namely: Guaifenesin (expectorant), Bromhexine hydrochloride (mucolytic agent), Terbutaline sulphate (bronchodilator) and Menthol (cooling agent). Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus and making it easier for airway passage. Bromhexine hydrochloride belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose, making it easier to cough it out. Terbutaline sulphate belongs to the class of bronchodilators that relaxes muscles and widens the airways making breathing easier in people with respiratory complications. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation due to cough deposition. Together, Bro-Zedex Syrup helps provide relief from cough.

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bro-Zedex Syrup

  • Diarrhoea
  • Nausea
  • Vomiting
  • Drowsiness
  • Headache
  • Dizziness
  • Stomach upset

Drug Warnings

Consult your doctor if you are pregnant or planning for pregnancy. Avoid taking Bro-Zedex Syrup while breastfeeding as it is excreted in breast milk and may cause adverse effects in the baby. Inform your doctor if you have diabetes, fits, high blood pressure, glaucoma, chronic bronchitis (swelling and irritation of the lining of airways), emphysema (lung condition resulting in shortness of breath), overactive thyroid, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), ulcers in the stomach or intestines, kidney, liver or heart problems.

Drug Interactions

Drug-Drug Interaction: Bro-Zedex Syrup may interact with an anti-hypertensive agent (propranolol), hormone (epinephrine), water pills (furosemide), anti-allergic drugs (promethazine), uterine stimulant (oxytocin), bronchodilators (formoterol, dyphylline), anti-sickness drug (ondansetron).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: Inform your doctor if you have diabetes, fits, high blood pressure, glaucoma, cough from a long time, chronic bronchitis (swelling and irritation of the lining of airways), or emphysema (lung condition resulting in shortness of breath).

Drug-Drug Interactions Checker List

  • PROPRANOLOL
  • EPINEPHRINE
  • FUROSEMIDE
  • PROMETHAZINE
  • OXYTOCIN
  • FORMOTEROL
  • DYPHYLLINE
  • ONDANSETRON

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods.
  • Replace baked foods, fried foods, white bread, white pasta, french fries, sugary desserts and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid a dry throat. It also helps loosen mucus.
  • Avoid citrus fruits as it may worsen the cough.
  • Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Special Advise

  • Regularly monitor blood sugar levels while taking Bro-Zedex Syrup if you have diabetes, as it may increase blood sugar levels.

Disease/Condition Glossary

Cough: Coughing is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. Cough may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus and other matter) from the lungs. A dry cough does not produce sputum. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. 

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Alcohol

Caution

The interaction of alcohol with Bro-Zedex Syrup is unknown. Please consult a doctor before consuming alcohol with Bro-Zedex Syrup .

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Pregnancy

Unsafe

Bro-Zedex Syrup is contraindicated in pregnant women, especially in the first 3 months of pregnancy, as it may cause birth defects. Therefore, please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Bro-Zedex Syrup is excreted in breast milk and may cause adverse effects in the baby. Hence, it is not recommended for breastfeeding mothers.

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Driving

Caution

Bro-Zedex Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Bro-Zedex Syrup .

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Liver

Caution

If you have any concerns regarding the use of Bro-Zedex Syrup in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Bro-Zedex Syrup in patients with kidney problems, please consult a doctor.

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Children

Caution

Bro-Zedex Syrup should be used with caution in children, especially below 2 years of age, if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India
Other Info - BRO0003

Author Details

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FAQs

Bro-Zedex Syrup is used to treat cough associated with vicious and excessive mucus in patients with asthma and COPD (chronic obstructive pulmonary disorder).
Bro-Zedex Syrup contains Guaifenesin, Bromhexine hydrochloride, Terbutaline sulphate and Menthol. Guaifenesin works by increasing the volume of fluid in the airways, reduce the stickiness of mucus and helps to remove it from the airways. Bromhexine hydrochloride works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Thereby, helps to cough out easily. Terbutaline sulphate relaxes muscles and widens the airways. Thereby, makes breathing easier. Menthol produces a cooling sensation and provides relief from minor throat irritation.
Bro-Zedex Syrup may cause drowsiness or dizziness. It is not necessary for everyone taking Bro-Zedex Syrup to experience this side effect. Avoid driving if you feel drowsy or dizzy after taking Bro-Zedex Syrup .
Bro-Zedex Syrup should be used with caution in diabetic patients if prescribed by a doctor. However, regular monitoring of blood sugar levels is recommended while taking Bro-Zedex Syrup as it may increase blood sugar levels.
You are not recommended to take propranolol with Bro-Zedex Syrup as it may reduce the effectiveness of both medicines. Also, propranolol may cause a narrowing of airways sometimes, which may trigger severe asthmatic attacks or worsen breathing problems. However, you should consult a doctor before taking other medicines with Bro-Zedex Syrup .
Bro-Zedex Syrup should be used with caution in hyperthyroid (overactive thyroid) patients as it may worsen the condition. Inform your doctor if you have hyperthyroidism so that the dose may be adjusted appropriately. However, regular monitoring of thyroid hormone levels is recommended while taking Bro-Zedex Syrup .
You are recommended to take Bro-Zedex Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache, please consult your doctor.
You are not recommended to stop taking Bro-Zedex Syrup without consulting your doctor as it may worsen the cough or cause recurring symptoms. Therefore, take Bro-Zedex Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Bro-Zedex Syrup , please consult your doctor.

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