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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:45 PM IST

Brivazen Injection 5 ml is used to treat Partial-onset seizures. It contains Brivaracetam, which reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Thus, it decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures. Common side effects include somnolence (excess sleepiness), dizziness, fatigue (feeling overtired), nausea, and vomiting.

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Composition :

BRIVARACETAM-10MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Brivazen Injection 5 ml

Brivazen Injection 5 ml belongs to a group of medications called 'anti-convulsants'. It is used for treating partial-onset seizures (seizures involving only one part of the brain) in people with epilepsy (fits) in patients one month of age and older. Partial-onset seizures are characterized by abnormal electrical activity in only one brain hemisphere. Common symptoms are involuntary muscle contractions, followed by relaxation on one side of the body, uncontrolled head or eye movements, rapid heart rate, and a tingling sensation on the skin.

Brivazen Injection 5 ml contains '‘Brivaracetam' that reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Thus, Brivazen Injection 5 ml decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures.

A qualified healthcare professional will administer Brivazen Injection 5 ml. In some cases, you may experience certain common side effects such as somnolence (excess sleepiness), dizziness, fatigue (feeling overtired), nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Brivazen Injection 5 ml for as long as your doctor has prescribed. Brivazen Injection 5 ml should be gradually withdrawn, so please do not stop taking Brivazen Injection 5 ml without consulting your doctor. Before taking the Brivazen Injection 5 ml, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Inform your doctor if you are pregnant or planning to become pregnant. You should not breastfeed unless the doctor advises. Consult your doctor immediately if you experience suicidal tendencies. It is recommended not to drive or operate machinery as Brivazen Injection 5 ml may cause tiredness and fatigue. It is recommended not to take alcoholic beverages while on Brivaracetam therapy.

Uses of Brivazen Injection 5 ml

Treatment of Partial-onset seizures

Medicinal Benefits

Brivazen Injection 5 ml belongs to a group of medicines called anticonvulsants or anti-epileptics used to control partial-onset seizures in the treatment of epilepsy (fits). Brivazen Injection 5 ml consists of ‘Brivaracetam' that works by reducing the electrical impulses and subsequent firing of the nerve impulses that cause fits. Brivazen Injection 5 ml decreases the brain's excessive and abnormal nerve activity, thereby helping control seizures.

Side Effects of Brivazen Injection 5 ml

  • Drowsiness
  • Tiredness
  • Fatigue
  • Asthenia (weakness)
  • Malaise (General discomfort)
  • Hypersomnia (Excessive sleepiness)
  • Sedation
  • Lethargy (a lack of energy)
  • Dizziness
  • Vertigo (Spinning sensation)
  • Balance disorder
  • Ataxia (Impaired coordination)
  • Nystagmus (Involuntary eye movement)
  • Gait disturbance (a manner of walking or moving on foot)
  • Abnormal coordination

Directions for Use

A qualified healthcare professional will administer Brivazen Injection 5 ml. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking the Brivazen Injection 5 ml, inform your doctor about all your medical conditions, allergic conditions, and all medications you are using. Inform your doctor if you are pregnant or planning to become pregnant. If you become pregnant while taking Brivazen Injection 5 ml, call your doctor. You should not breastfeed unless the doctor advises. Consult your doctor immediately if you experience suicidal tendencies. It is recommended not to drive or operate machinery as Brivazen Injection 5 ml may cause tiredness and fatigue. It is recommended not to take alcoholic beverages while on Brivaracetam therapy. Do not stop Brivazen Injection 5 ml without first talking to a healthcare provider. Stopping Brivazen Injection 5 ml suddenly can cause serious problems. Sometimes, it may lead to seizures that will not stop (status epilepticus).

Therapeutic Class

ANTICONVULSANT

Drug-Drug Interactions

verifiedApollotooltip
BrivaracetamKetamine
Severe
BrivaracetamEsketamine
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for energy generation.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures are and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

How Brivazen Injection 5 ml Works

Brivazen Injection 5 ml contains '‘Brivaracetam' that reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Thus, Brivazen Injection 5 ml decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures.

What if I have taken an overdose of Brivazen Injection 5 ml

Since Brivazen Injection 5 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Brivazen Injection 5 ml may cause somnolence and dizziness.
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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and sleepiness.

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Pregnancy

Caution

There are no adequate and well-controlled studies on pregnant women. Inform your doctor before receiving the Brivazen Injection 5 ml if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

There has been no significant research on using Brivazen Injection 5 ml in breastfeeding/nursing moms. So, let your doctor know if you are a nursing mother before taking Brivazen Injection 5 ml; your doctor will decide whether Brivazen Injection 5 ml can be taken by breastfeeding mothers.

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Driving

Unsafe

Brivazen Injection 5 ml may cause somnolence (excess sleepiness) and fatigue (feeling overtired). It impacts your daily activities; hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Dose adjustments are recommended for patients with hepatic impairment. So inform your doctor before receiving the Brivazen Injection 5 ml if you have a history of liver impairments.

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Kidney

Caution

Brivazen Injection 5 ml is recommended not to be used in end-stage renal disease patients undergoing dialysis. Inform your doctor before receiving the Brivazen Injection 5 ml if you have a history of kidney diseases/conditions.

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Children

Safe if prescribed

Your doctor will prescribe only if the benefits outweigh the risks.

Country of origin

INDIA

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - BRI0564

Author Details

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FAQs

Brivazen Injection 5 ml is used to treat Partial-onset seizures.
Brivazen Injection 5 ml contains Brivaracetam, an antiepileptic that attaches itself to specific sites (SV2A) on nerve cell surfaces. This activity may suppress the brain's abnormal activity and prevents the spread of electrical signals that cause seizures.
No, Brivazen Injection 5 ml should not be stopped even if you start feeling better. Suddenly stopping the Brivazen Injection 5 ml may cause continuous seizures, which can be difficult to control. To treat your condition effectually, continue taking Brivazen Injection 5 ml for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Brivazen Injection 5 ml; your doctor will gradually reduce the dose to avoid precipitating seizures.
Brivazen Injection 5 ml may cause suicidal thoughts such as killing or harming yourself. People taking Brivazen Injection 5 ml should be closely monitored for suicidal thoughts or behaviour. Speak with your doctor immediately if you need to.
Pay close attention to any changes in mood, behaviour, thoughts, or feelings, especially if they are sudden.

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