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  1. Home
  2. Medicine

  3. Brisval ER 250 Tablet 10's

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Brisval ER 250 Tablet is used to treat seizures. Besides this, it is also used to treat manic episodes associated with bipolar disorder and prevent migraine symptoms. It contains Valproic acid which works by reducing abnormal electrical activity in the brain. It also produces a calming effect and limits the transmission of pain signals. This medicine may sometimes cause side effects such as nausea, upset stomach, tremors, sleepiness, headache, and weight gain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Brisval ER 250 Tablet 10's, Pack of 10 TabletS
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Composition :

VALPROIC ACID-250MG

Manufacturer/Marketer :

Madbris Lifesciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Brisval ER 250 Tablet

Brisval ER 250 Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. In addition, Brisval ER 250 Tablet also treats manic episodes associated with bipolar disorder. Besides this, it can also prevent migraine symptoms (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state.

Brisval ER 250 Tablet contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Brisval ER 250 Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Brisval ER 250 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Brisval ER 250 Tablet should be taken as prescribed by the doctor. You may sometimes experience nausea, upset stomach or stomach pain, tremors (shakes), sleepiness, headache, weight gain and thinning hair. Most of these side effects are temporary and will go away on their own. However, if you suffer these adverse effects on a regular basis, you should consult your doctor.

Inform your doctor if you are allergic to any components present in Brisval ER 250 Tablet . If you are pregnant, do not take Brisval ER 250 Tablet because it may cause serious congenital defects. Use effective contraception if you are of childbearing age while taking Brisval ER 250 Tablet . If you are breastfeeding, inform your doctor before taking Brisval ER 250 Tablet . As Brisval ER 250 Tablet causes sleepiness and dizziness, do not drive or operate machinery. Avoid drinking alcohol with Brisval ER 250 Tablet as it may cause dizziness and tiredness. To rule out any negative effects, keep your doctor updated about your health condition and medications.

Uses of Brisval ER 250 Tablet

Brisval ER 250 Tablet is used for the treatment of Epilepsy (fits), Bipolar disorder, Migraine.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Brisval ER 250 Tablet contains Valproic acid, an anticonvulsant (or anti-epileptic) medicine that reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Brisval ER 250 Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Brisval ER 250 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

How Brisval ER 250 Tablet Works

Brisval ER 250 Tablet contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Brisval ER 250 Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Brisval ER 250 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Brisval ER 250 Tablet

  • Stomach pain
  • Feeling or being sick
  • Diarrhoea
  • Dry or sore mouth or swollen gums
  • Shakes (tremors) in a part of your body
  • Unusual eye movements
  • Feeling tired or sleepy
  • Headache
  • Weight gain
  • Thinning hair, or changes to the colour or texture of your hair
  • Irregular or delayed periods

What if I have taken an overdose of Brisval ER 250 Tablet

Take Brisval ER 250 Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include sleepiness, irregular heartbeat, and coma (loss of consciousness for a period of time). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Before taking the Brisval ER 250 Tablet , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby, or are breastfeeding. You should not become pregnant while you are receiving Brisval ER 250 Tablet . Consult your doctor immediately if you become pregnant while receiving a Brisval ER 250 Tablet . Alcohol should be avoided during treatment with this medicine. You must not drive or operate machinery while receiving Brisval ER 250 Tablet .

Drug-Drug Interactions

verifiedApollotooltip
DivalproexGlycerol phenylbutyrate
Critical
DivalproexKetoconazole
Severe

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Brisval ER 250 Tablet 10's:
Coadministration of Glycerol phenylbutyrate and Brisval ER 250 Tablet 10's can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Brisval ER 250 Tablet 10's together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DivalproexKetoconazole
Severe
How does the drug interact with Brisval ER 250 Tablet 10's:
Coadministration of Ketoconazole and Brisval ER 250 Tablet 10's may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Brisval ER 250 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain, fatigue, nausea, vomiting, stomach pain, dark urine, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexErtapenem
Severe
How does the drug interact with Brisval ER 250 Tablet 10's:
Coadministration of Ertapenem with Brisval ER 250 Tablet 10's may reduce the blood levels of Brisval ER 250 Tablet 10's and increase the risk of developing seizures.

How to manage the interaction:
Although there is a possible interaction, ertapenem can be taken with Brisval ER 250 Tablet 10's if prescribed by the doctor. Consult the doctor if you experience loss of seizure control or changes in behaviour. Do not stop using any medications without talking to your doctor.
DivalproexSodium oxybate
Severe
How does the drug interact with Brisval ER 250 Tablet 10's:
Co-administration of Sodium oxybate and Brisval ER 250 Tablet 10's can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Sodium oxybate and Brisval ER 250 Tablet 10's can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, sweating, palpitations, and shortness of breath, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexEsketamine
Severe
How does the drug interact with Brisval ER 250 Tablet 10's:
Coadministration of Esketamine and Brisval ER 250 Tablet 10's can increase the side effects of esketamine.

How to manage the interaction:
Although taking Brisval ER 250 Tablet 10's and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any symptoms like drowsiness and impaired motor coordination, consult the doctor immediately. Do not stop using any medications without talking to your doctor.
DivalproexLeflunomide
Severe
How does the drug interact with Brisval ER 250 Tablet 10's:
Co-administration of Brisval ER 250 Tablet 10's and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Brisval ER 250 Tablet 10's and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DivalproexLomitapide
Severe
How does the drug interact with Brisval ER 250 Tablet 10's:
Co-administration of Brisval ER 250 Tablet 10's and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Brisval ER 250 Tablet 10's and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.
DivalproexMipomersen
Severe
How does the drug interact with Brisval ER 250 Tablet 10's:
Co-administration of Brisval ER 250 Tablet 10's and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Brisval ER 250 Tablet 10's and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.
DivalproexKetamine
Severe
How does the drug interact with Brisval ER 250 Tablet 10's:
Co-administration of Brisval ER 250 Tablet 10's and Ketamine can increase the risk of side effects.

How to manage the interaction:
Co-administration of Brisval ER 250 Tablet 10's and Ketamine can lead to an interaction, it can be taken if advised by your doctor. If you have any symptoms such as dizziness, drowsiness, shortness of breath, or impairment in thinking and motor coordination, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
DivalproexTeriflunomide
Severe
How does the drug interact with Brisval ER 250 Tablet 10's:
Co-administration of Brisval ER 250 Tablet 10's and teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Brisval ER 250 Tablet 10's and teriflunomide can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Adolescents and adults are advised to follow the Atkins diet (high fat, low carbohydrate).
  • Exercising on a regular basis aids with weight maintenance and general health.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and drinking alcohol.
  • Meditation and yoga can help reduce stress, reduce pain sensitivity, and increase coping abilities.
  • Have a seizure response plan in place, and make sure everyone around you knows what to do in the event of a seizure.
  • Prepare your living environment; simple changes may help reduce the risk of physical damage during a seizure.
  • Understand what causes seizures and try to reduce or avoid them.
  • Please keep your overall health in mind, as it can aid in the reduction of seizure activity.
  • Install an alarm or an emergency gadget to summon help during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Brisval ER 250 Tablet Substitute

Substitutes safety advice

  • Dicorate ER 250 Tablet 10's

    ₹10.38per tablet

  • Valance Solution 100 ml

    ₹2.50per tablet

  • Divaprime OD 250 Tablet 10's

    ₹10.80per tablet

  • Dv Exel-250 Tablet 10's

    ₹12.60per tablet

  • Dvlyf XR 250 Tablet 10's

    ₹8.28per tablet

Product Substitutes

Info icon

Dicorate ER 250 Tablet 10's

₹103.8

MRP ₹118

Info icon

Valance Solution 100 ml

₹249.8

MRP ₹277.5

Info icon

Divaprime OD 250 Tablet 10's

₹108

MRP ₹120

Info icon

Dv Exel-250 Tablet 10's

₹126

MRP ₹140

Info icon

Dvlyf XR 250 Tablet 10's

₹82.8

MRP ₹92

Info icon

Valbest-250 mg ER Tablet 10's

₹71.3

MRP ₹81

Info icon

Diwok-Od 250Mg Er Tablet 10'S

₹54.9

MRP ₹61

Info icon

Valcare-250 Tablet 10's

₹76.5

MRP ₹85

Info icon

Solpin-ER 250 mg Tablet 10's

₹46.44

MRP ₹51.6

Info icon

Divato OD-250 Tablet 10's

₹59.9

MRP ₹66.5

Info icon

Dicopril-ER 250 Tablet 10's

₹103.5

MRP ₹115

Info icon

Divaldec ER-250 Tablet 10's

₹86.4

MRP ₹96

Info icon

Divvs ER 250 Tablet 10's

₹75.6

MRP ₹84

Info icon

Discern-250-OD Tablet 10's

₹61.2

MRP ₹68

Info icon

Valpam-250 ER Tablet 10's

₹82.8

MRP ₹92

Info icon

Divalant ER 250 Tablet 10's

₹63.9

MRP ₹71

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Alcohol

Caution

Do not consume alcohol while taking Brisval ER 250 Tablet as alcohol can worsen the side effects of the Brisval ER 250 Tablet , including sleepiness and dizziness.

bannner image

Pregnancy

Unsafe

Brisval ER 250 Tablet is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of a cleft lip, which is a congenital disability in the unborn baby. If you are a female able to have a baby, you must use an effective method of birth control (contraception) without interruption during your entire treatment with Brisval ER 250 Tablet .

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Breast Feeding

Caution

Brisval ER 250 Tablet passes into breast milk and may harm your infant. Please consult a doctor if you are breastfeeding before taking Brisval ER 250 Tablet . Breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy.

bannner image

Driving

Caution

Brisval ER 250 Tablet may cause dizziness, drowsiness or tiredness in some people. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking Brisval ER 250 Tablet .

bannner image

Liver

Caution

Inform your doctor before receiving the Brisval ER 250 Tablet if you have a history of liver diseases/conditions. Extreme caution is recommended in patients with impaired liver function. Your doctor will weigh the benefits and potential risks before prescribing Brisval ER 250 Tablet .

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment.

bannner image

Children

Consult your doctor

Use is not recommended for children less than ten years. Your doctor will decide the dose based on your child's condition if more than ten years.

FAQs

Brisval ER 250 Tablet is used to treat epilepsy/seizures/fits. In addition, it also helps treat manic episodes associated with bipolar disorder and prevent migraine symptoms (like a headache).
Brisval ER 250 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures.
Brisval ER 250 Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.
Brisval ER 250 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition which is characterized by intense headaches.
Brisval ER 250 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.
Use an effective method of contraception during the treatment with Brisval ER 250 Tablet . Avoid getting pregnant while taking Brisval ER 250 Tablet as it could lead to serious birth defects. Do not stop taking Brisval ER 250 Tablet and consult your doctor immediately if you become pregnant.
Brisval ER 250 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.
Brisval ER 250 Tablet may cause common side effects such as nausea, vomiting, headache, sleepiness, tremor, weakness, dizziness, stomach pain, and weight gain. If these side effects persist or worsen, please consult your doctor.
Brisval ER 250 Tablet contains Valproic acid as its active ingredient.
Take Brisval ER 250 Tablet with or without food as advised by your doctor.
You are recommended to avoid alcohol consumption while taking Brisval ER 250 Tablet as it may worsen the side effects of the Brisval ER 250 Tablet , including sleepiness and dizziness.
No, Brisval ER 250 Tablet does not cause addiction. However, Brisval ER 250 Tablet should be used as per dose and duration prescribed by your doctor. Do not self-medicate.
Brisval ER 250 Tablet does not cure epilepsy, it only helps to prevent the seizures. However, you have to take Brisval ER 250 Tablet for as long as it is advised by your doctor. If you face any difficulty while taking Brisval ER 250 Tablet , consult your doctor.
If you stop taking Brisval ER 250 Tablet suddenly, it may increase the risk of recurrence of seizures. Therefore, it should be stopped gradually. If you feel the need to stop taking Brisval ER 250 Tablet , please consult your doctor.
Some birth control pills (oestrogen-containing birth control pills) may lower the levels of Brisval ER 250 Tablet in blood. Thus, inform your doctor if you are using birth control pills and discuss with your doctor about the suitable method of contraception.
Brisval ER 250 Tablet is safe to take for long time in many patients if prescribed by a doctor. In rare cases, prolonged use of Brisval ER 250 Tablet may weaken your bones, thereby increasing their risk of breaking easily (osteopenia and osteoporosis). Get regular checkups done for bone health if you are taking Brisval ER 250 Tablet for a long time.
Brisval ER 250 Tablet may cause hair thinning, hair colour changes and even hair loss. If you have any concerns regarding this, please ask your doctor if it is possible to lower the dose of Brisval ER 250 Tablet . Your hair may regrow after either lowering your dose or changing medication.

Country of origin

India

Manufacturer/Marketer address

2099, Street Number 1, Prem Nagar, Patel Nagar, CENTRAL DELHI, Delhi 110008
Other Info - BRI0812

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Author Details

Doctor imageDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/mtm/valproic-acid.html
  2. https://www.medicines.org.uk/emc/files/pil.6102.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/018081s065_018082s048lbl.pdf
  4. https://www.nhs.uk/medicines/valproic-acid/
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