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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 22, 2024 | 7:37 PM IST
Brinzagan Ophthalmic Suspension 5 ml is used to treat increased pressure in eye conditions. It contains Brinzolamide, which reduces the secretion of eye fluid called aqueous humour that maintains pressure in the eyeball and in turn lowers the raised pressure in the eye by reducing aqueous humour entry into the eyeball. Thus, it prevents eyes from getting blind in the conditions of open-angle type glaucoma and ocular hypertension. In some cases, you may experience side effects such as eye discharge, redness, itching, irritation or pain in the eyes, blurred vision, abnormal eye sensation and dry eyes. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type

OPHTHALMIC

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Brinzagan Ophthalmic Suspension 5 ml

Brinzagan Ophthalmic Suspension 5 ml is used to treat increased pressure in eye conditions. Glaucoma is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. Ocular hypertension is increased pressure in the eye due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow).

Brinzagan Ophthalmic Suspension 5 ml contains Brinzolamide, which works by inhibiting the action of carbonic anhydrase enzyme and decreasing bicarbonate production, which is essential for the production of fluid in the eye (aqueous humour).  Thus, it reduces the secretion of eye fluid called 'aqueous humour' that maintains pressure in the eyeball and, in turn, lowers the raised pressure in the eye by reducing aqueous humour entry into the eyeball. Thus, Brinzagan Ophthalmic Suspension 5 ml prevents eyes from getting blind in the conditions of open-angle type glaucoma and ocular hypertension. 

Use Brinzagan Ophthalmic Suspension 5 ml as prescribed. Brinzagan Ophthalmic Suspension 5 ml is only for use in the eyes. Do not swallow or inject Brinzagan Ophthalmic Suspension 5 ml. Your doctor will advise you on how many drops to instil based on your medical condition. In some cases, you may experience eye discharge, redness, itching, irritation or pain in the eyes, blurred vision, abnormal eye sensation and dry eyes. Most of these side effects of Brinzagan Ophthalmic Suspension 5 ml do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to Brinzagan Ophthalmic Suspension 5 ml or any other medicines, please tell your doctor. Brinzagan Ophthalmic Suspension 5 ml is not recommended for children below 18 years of age. You are not advised to use Brinzagan Ophthalmic Suspension 5 ml if you are pregnant, breastfeeding or have severe kidney problems or hyperchloraemic acidosis (excessive acidity in the blood). You are advised to remove soft contact lenses before using Brinzagan Ophthalmic Suspension 5 ml as it may cause discolouration of the soft contact lens. If you have any new eye problem or an eye infection or notice any allergic reactions such as itching or redness of the eye or skin rash, please consult your doctor immediately. You are advised to maintain a 5-minute time gap between using Brinzagan Ophthalmic Suspension 5 ml and other eye drops. If you have dry eyes, cornea problems, narrow-angle glaucoma, pseudoexfoliative glaucoma, pigmentary glaucoma, kidney or liver problems, before taking Brinzagan Ophthalmic Suspension 5 ml.

Uses of Brinzagan Ophthalmic Suspension 5 ml

Treatment of Glaucoma (open-angle type) and ocular hypertension (high eye pressure).

Medicinal Benefits

Brinzagan Ophthalmic Suspension 5 ml contains Brinzolamide, which is used to treat increased pressure in the eye in conditions such as glaucoma (damage of optic nerve) and ocular hypertension (high fluid pressure inside the eye). Brinzagan Ophthalmic Suspension 5 ml inhibits the action of carbonic anhydrase enzyme and decreases bicarbonate production, which is essential for the production of aqueous humour.  Thereby, it reduces the secretion of aqueous humour (a liquid that maintains normal pressure in the eyeball) and lowers the pressure in the eye by reducing aqueous humour entry into the eyeball.

Directions for Use

Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes. Please do not touch the container tip to the eye, eyelids, or surrounding areas as it may contaminate Brinzagan Ophthalmic Suspension 5 ml and cause eye infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Brinzagan Ophthalmic Suspension 5 ml

  • Eye discharge

  • Redness, itching, irritation or pain in the eyes

  • Blurred vision

  • Abnormal eye sensation

  • Dry eyes

Drug Warnings

If you are allergic to Brinzagan Ophthalmic Suspension 5 ml or any other medicines, please tell your doctor. Brinzagan Ophthalmic Suspension 5 ml is not recommended for children below 18 years of age. You are not advised to use Brinzagan Ophthalmic Suspension 5 ml if you are pregnant, breastfeeding, or have severe kidney problems or hyperchloraemic acidosis (excessive acidity in the blood). You are advised to remove soft contact lenses before using Brinzagan Ophthalmic Suspension 5 ml as it may cause discoloration of the soft contact lens. If you get any new eye problem, an eye infection, or notice any allergic reactions such as itching or redness of the eye and skin rash, please consult your doctor immediately. You are advised to maintain a 5 minutes time gap between using Brinzagan Ophthalmic Suspension 5 ml and other eye drops. Please do not touch the container tip to the eye, eyelids, or surrounding areas as it may contaminate Brinzagan Ophthalmic Suspension 5 ml and cause eye infections. If you have dry eyes, cornea problems, narrow-angle glaucoma, pseudoexfoliative glaucoma, or pigmentary glaucoma kidney or liver problems, before taking Brinzagan Ophthalmic Suspension 5 ml.

Drug Interactions

Drug-Drug Interaction: Brinzagan Ophthalmic Suspension 5 ml may have interaction with medicines used to treat glaucoma (dorzolamide, acetazolamide).

Drug- Food Interaction: No interactions found.

Drug-Disease Interaction: If you have dry eyes, cornea problems, narrow-angle glaucoma, pseudoexfoliative glaucoma or pigmentary glaucoma kidney or liver problems, before taking Brinzagan Ophthalmic Suspension 5 ml.

Drug-Drug Interactions Checker List

  • DORZOLAMIDE
  • ACETAZOLAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid baked foods such as cakes, cookies, donuts, or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage the optic nerve.

  • Please cut down your coffee intake as it may increase pressure in the eye and replace coffee with green tea.

  • Avoid exercises such as any position where the head is lower than the body like inverted yoga poses as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

Special Advise

  • You are recommended to avoid wearing contact lenses while using Brinzagan Ophthalmic Suspension 5 ml as it may cause discoloration of soft contact lenses.

  • Do not use Brinzagan Ophthalmic Suspension 5 ml if you have used any steroid eye injection within six months, undergone any other intraocular surgery (like cataract surgery) within 6 months, or have had any laser surgery within 12 months.

Disease/Condition Glossary

Glaucoma: It is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. If it is not treated in time, it may cause blindness. Usually, there are no symptoms of glaucoma initially except for the gradual slow loss of vision. However, some symptoms include visible rainbow-coloured circles around bright lights or blurred vision. Rarely, glaucoma can develop suddenly with intense pain in the eye, visual disturbance, or nausea.

Ocular hypertension: It is a condition caused by poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow). This leads to the build-up of excess fluid in the eye, resulting in increased pressure inside the eye without any damage to the optic nerve. If ocular hypertension is not controlled, it may lead to glaucoma.

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Alcohol

Caution

The interaction of alcohol with Brinzagan Ophthalmic Suspension 5 ml is unknown. Please consult a doctor before consuming alcohol with Brinzagan Ophthalmic Suspension 5 ml.

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Pregnancy

Unsafe

Brinzagan Ophthalmic Suspension 5 ml is a Category C pregnancy drug and is not recommended for use during pregnancy unless your doctor considers it essential.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Brinzagan Ophthalmic Suspension 5 ml. Please consult a doctor before using Brinzagan Ophthalmic Suspension 5 ml in breastfeeding mothers.

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Driving

Caution

Brinzagan Ophthalmic Suspension 5 ml may cause blurred vision in some people. So, drive only when your vision is clear after taking Brinzagan Ophthalmic Suspension 5 ml.

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Liver

Caution

If you have any concerns regarding the use of Brinzagan Ophthalmic Suspension 5 ml in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Brinzagan Ophthalmic Suspension 5 ml in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Brinzagan Ophthalmic Suspension 5 ml is not recommended for children below 18 years of age, as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

No.3, Kasturba Road, Level 2, Prestige Obelisk, Bangalore – 560 001., KARNATAKA, INDIA
Other Info - BRI0390

Author Details

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FAQs

Brinzagan Ophthalmic Suspension 5 ml is used to treat glaucoma (open-angle type) and ocular hypertension (high eye pressure).
Brinzagan Ophthalmic Suspension 5 ml contains Brinzolamide that works by inhibiting the action of carbonic anhydrase enzyme and decreases bicarbonate production that is essential for the production of aqueous humour. Thereby, it reduces the secretion of aqueous humour (a liquid that maintains normal pressure in the eyeball) and lowers the pressure in the eye by reducing aqueous humour entry into the eyeball.
You are recommended to wash your hands first and tilt your head back and gently pull the lower eyelid downwards. Then, press the bottom of the bottle gently by holding it upside down to instil one drop into the affected eye without touching the tip of the bottle to the eye or surrounding areas in order to avoid contamination. Finally, replace the cap tightly after use. After applying Brinzagan Ophthalmic Suspension 5 ml, you are advised to apply to the corner of the eye by pressing a finger to stop eye drops from spreading into the rest of the body.
No, you are not recommended to wear contact lenses while using Brinzagan Ophthalmic Suspension 5 ml as it contains benzalkonium chloride, a preservative that changes the colour of the contact lens as it may be absorbed by a soft contact lens. Benzalkonium chloride also causes irritation in the eye especially if you have disorders of the cornea (transparent layer at the front of the eye) or dry eyes. Therefore, you are advised to remove contact lenses before applying Brinzagan Ophthalmic Suspension 5 ml and reinsert after 15 minutes of using Brinzagan Ophthalmic Suspension 5 ml. Also, inform your doctor if you experience pain, stinging or abnormal sensation in the eye after using Brinzagan Ophthalmic Suspension 5 ml.
You are recommended to maintain a minimum of 5 minutes time gap between using Brinzagan Ophthalmic Suspension 5 ml and other eye drops and administer eye ointments in the last.
Yes, Brinzagan Ophthalmic Suspension 5 ml may cause temporary blurred vision. Therefore, you are recommended to wait until your vision is clear before driving or operating heavy machinery.
You are not recommended to stop using Brinzagan Ophthalmic Suspension 5 ml without consulting your doctor as it may increase pressure in the eyes and may lead to loss of vision. Therefore, use Brinzagan Ophthalmic Suspension 5 ml for as long as your doctor has prescribed it, and if you experience any difficulty while taking Brinzagan Ophthalmic Suspension 5 ml, please consult your doctor.
Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.
Brinzagan Ophthalmic Suspension 5 ml should be used as prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Brinzagan Ophthalmic Suspension 5 ml may cause headache as a side effect. Rest in a quiet/dark room, massage gently, and use a hot/cold compress on the head and neck.
Brinzagan Ophthalmic Suspension 5 ml may cause side effects like eye discharge, redness, itching, irritation or pain in the eyes, blurred vision, abnormal eye sensation and dry eyes. If the side effects worsen or persist, please consult your doctor.
Other eye drops should be used with Brinzagan Ophthalmic Suspension 5 ml if prescribed by the doctor. Maintain a gap of 10 minutes between Brinzagan Ophthalmic Suspension 5 ml and other eye medicines.
Avoid using Brinzagan Ophthalmic Suspension 5 ml if you are allergic to any of its components. Inform the doctor if you are pregnant, breastfeeding, have severe kidney problems or have hyperchloraemic acidosis (excessive acidity in the blood).

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