Bortecine Injection belongs to a group of anti-cancer medicines used to treat adult patients with multiple myeloma and mantle cell lymphoma who have received at least one prior therapy. Multiple myeloma, also known as myeloma, is a type of bone marrow cancer it affects several areas of the body, such as the spine, skull, pelvis, and ribs. Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma (NHL). It develops when B-cells (also called B-lymphocytes) become abnormal. B-cells are white blood cells that fight infection.

Bortecine Injection contains 'Bortezomibx' that works by interfering with how proteasomes work, which may cause cancer cells to die and may stop cancer from growing and eventually kills them.

Bortecine Injection is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection into your vein (intravenously or IV) or under your skin (subcutaneously or SC). Bortecine Injection must not be administered into your spinal fluid (intrathecally). You may experience nausea, diarrhoea, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), peripheral neuropathy (nerves malfunction), fatigue, neuralgia, anaemia, leukopenia, constipation, vomiting, lymphopenia, rash, pyrexia, and anorexia. Most of these side effects of Bortecine Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Bortecine Injection for as long as your doctor has prescribed. Do not stop the Bortecine Injection midway. Talk to your doctor before taking Bortecine Injection if you have allergies or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Avoid taking Bortecine Injection if you are pregnant or breastfeeding because this Bortecine Injection can cause harmful effects on the unborn baby. Both women and men using this Bortecine Injection should use birth control to avoid pregnancy.

Bortecine Injection contains the active substance bortezomib, also-called ‘proteasome inhibitor. Proteasomes play an important role in controlling cell function and growth. By interfering with their function, thereby it can kill cancer cells. Bortecine Injection is used to treat multiple myeloma (a cancer of the bone marrow) and mantle cell lymphoma (a type of cancer affecting the lymph nodes) in 18 years or older patients. It can be used alone or together with other medicines.

• Nausea
• Diarrhoea
• Thrombocytopenia (low blood platelet count)
• Neutropenia (too few neutrophils)
• Peripheral neuropathy (nerves malfunction)
• Fatigue (overtired)
• Neuralgia (pain in the head or face)
• Muscle pain, bone pain
• Anaemia (low red blood cell Count)
• Leukopenia (Low White Blood Cell Count)
• High blood pressure
• Constipation
• Dehydration
• Vomiting
• Loss of appetite
• Lymphopenia (Low lymphocytes Count)
• Rash
• Pyrexia (raised body temperature)
• Anorexia (lack or loss of appetite for food)
• Infections, including pneumonia, respiratory infections, bronchitis, fungal infections, coughing with phlegm, flu-like illness

To treat your condition effectually, continue taking Bortecine Injection for as long as your doctor has prescribed. Do not stop the Bortecine Injection midway. Talk to your doctor before taking Bortecine Injection if you have allergies or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. And also, inform your doctor if you have diabetes because this medicine can affect your blood glucose levels. Your doctor may require close monitoring of your blood glucose levels and change your diabetes medicine dose while being treated with Bortecine Injection. Avoid taking Bortecine Injection if you are pregnant because this Bortecine Injection can cause harmful effects on the unborn baby. Both women and men using this Bortecine Injection should use birth control to avoid pregnancy and for at least six months following treatment. Do not breastfeed during treatment with Bortecine Injection and four months after your final dose of Bortecine Injection.

Drug-Drug Interactions: Bortecine Injection interacts with antifungal medication (ketoconazole), HIV medication (ritonavir), antibiotic medication (rifampicin), epilepsy medications (carbamazepine, phenytoin or phenobarbital), depression medication (St. John’s Wort), and oral antidiabetics.

Drug-Food Interactions: No food interaction was found.

Drug-Disease Interactions: Inform your doctor before taking Bortecine Injection; it requires close monitoring if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), and hepatic disorders.

• KETOCONAZOLE
• RITONAVIR
• RIFAMPICIN
• CARBAMAZEPINE
• PHENYTOIN
• PHENOBARBITAL

• Eat a healthy diet and exercise regularly to maintain proper weight.
• Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
• Get optimal sleep, and rest well.
• Performing yoga may also help in improving both physical and mental health.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
• Avoid smoking and alcohol consumption.
• Avoid fast, fried, processed meats, refined carbs, and added sugars.

• Bortecine Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Bortecine Injection.
• Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, blood cell count in your blood.
• Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Bortecine Injection may make your skin sensitive to sunlight.

Multiple myeloma, also known as myeloma, is a type of bone marrow cancer it affects several areas of the body, such as the spine, skull, pelvis, and ribs.

Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma (NHL). It develops when B-cells (also called B-lymphocytes) become abnormal. B-cells are white blood cells that fight infection.

Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can invade and destroy surrounding healthy tissue, including organs.