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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:44 PM IST

Bivamax 250mg Injection is used to prevent the formation of blood clots. It works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack) or stroke, especially in people who have had heart surgery, known as angioplasty.

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Composition :

BIVALIRUDIN-250MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Bivamax 250mg Injection

Bivamax 250mg Injection belongs to the group of medicines called blood thinners used to prevent the formation of blood clots. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful for stopping bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels. Bivamax 250mg Injection is used in combination with aspirin during Percutaneous transluminal coronary angioplasty (PTCA) and Percutaneous coronary intervention (PCI) (angioplasty procedures) in unstable angina patients to reduce the chance of blood clot formation.

Bivamax 250mg Injection contains Bivalirudin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. This results in lower cardiovascular events like myocardial infarction (heart attack) or other severe chest pain-related problems.

Bivamax 250mg Injection will be administered by your doctor. So, do not self-administer. The dose of the medicine will be decided by your doctor based on your health condition. Bivamax 250mg Injection may cause certain side effects such as nose bleeds, skin rash, bleeding in the bowels, blood in urine, low haemoglobin, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme levels. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Bivamax 250mg Injection should not be used if you are allergic to it or if you ever had a brain stroke, bleeding in the brain or transient ischemic attack (stroke). Talk to your doctor before receiving Bivamax 250mg Injection if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems, have/had a heart problem, kidney disease or using any blood thinner medicine. Pregnant or breastfeeding mothers should inform the doctor before receiving this medicine. Bivamax 250mg Injection is not recommended for children as efficacy and safety have not been established.

Uses of Bivamax 250mg Injection

Prevention of blood clots

Medicinal Benefits

Bivamax 250mg Injection belongs to the group of medicines called antithrombolytic agents (direct thrombin inhibitors) used to prevent the formation of blood clots. Bivamax 250mg Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack) or stroke, especially in people who have had heart surgery, known as angioplasty.

Side Effects of Bivamax 250mg Injection

  • Nose bleeds
  • Skin rash
  • Bleeding in bowels
  • Blood in urine
  • Low haemoglobin
  • Bruising
  • Thrombocytopenia

Directions for Use

A trained healthcare professional will administer Bivamax 250mg Injection. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not receive Bivamax 250mg Injection if you are allergic to it or if you have a medical condition that causes bleeding from the stomach or intestine, had a transient ischemic attack (stroke) or if you are suffering from severe liver disease. Let your doctor know if you have bleeding problems, had/have a recent serious injury or surgery, kidney/liver disease, or are taking any blood thinner medicine before receiving this medicine. Consult your doctor immediately if you develop a medical condition called thrombotic thrombocytopenic purpura (blood disorder) while on treatment with Bivamax 250mg Injection. Pregnant or breastfeeding mothers should inform their doctor before receiving this medicine. Bivamax 250mg Injection is not recommended for children as efficacy and safety have not been established.

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

How Bivamax 250mg Injection Works

Bivamax 250mg Injection contains Bivalirudin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. This results in lower cardiovascular events like myocardial infarction (heart attack) or other severe chest pain-related problems.

What if I have taken an overdose of Bivamax 250mg Injection

Since Bivamax 250mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption while receiving Bivamax 250mg Injection to prevent unpleasant side effects.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Bivamax 250mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited data are available on the effect of Bivamax 250mg Injection on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Bivamax 250mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Bivamax 250mg Injection does not affect your ability to drive.

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Liver

Caution

Bivamax 250mg Injection should be used with caution in patients with liver impairment. Please inform your doctor if you have liver disease or any concerns regarding this.

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Kidney

Caution

Bivamax 250mg Injection should be used with caution in patients with kidney impairment. Please inform your doctor if you have kidney disease or any concerns regarding this.

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Children

Unsafe

Bivamax 250mg Injection is not recommended for use in children, as efficacy and safety have not been established.

Other Info - BIVA170

Author Details

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FAQs

Bivamax 250mg Injection is used to prevent blood clots.
Bivamax 250mg Injection works by inhibiting the clumping of platelets, thereby reducing the chance of blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack).
No, you are not recommended to take ibuprofen with Bivamax 250mg Injection as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Bivamax 250mg Injection.
Bivamax 250mg Injection may cause anaemia (low haemoglobin and low red blood cell count). So it would be best if you include iron-rich food in your diet to prevent anaemia.
Bivamax 250mg Injection does not affect the functioning of the liver. However, long-term use of Bivamax 250mg Injection may slightly increase the risk of mild liver damage, particularly in those with increased liver enzyme levels. Therefore, if you have any liver problem, please inform your doctor before starting Bivamax 250mg Injection.
It is best to avoid drinking alcohol while taking Bivamax 250mg Injection. Intake of alcohol might increase the risk of stomach or intestinal bleeding.
Store Bivamax 250mg Injection at controlled room temperature (15-25°C) in a cool and dry place. Do not freeze. Keep out of reach of children.
You might not feel any difference after taking Bivamax 250mg Injection, but you should continue taking it as prescribed by your doctor. Even though you don't notice any difference, you will still receive all benefits of Bivamax 250mg Injection.
Bivamax 250mg Injection should not be taken by individuals with allergies, bleeding issues, strokes, liver disease, or taking any blood thinners. It is important to inform your doctor if you develop thrombotic thrombocytopenic purpura while on treatment with Bivamax 250mg Injection. Pregnant or breastfeeding mothers should inform your doctor before receiving Bivamax 250mg Injection. Bivamax 250mg Injection is not recommended for children as efficacy and safety have not been established.
No, Bivamax 250mg Injection does not usually cause hair loss. However if you notice hair loss while on treatment with Bivamax 250mg Injection, please consult your doctor.
The common side effects of Bivamax 250mg Injection are nose bleeds, skin rash, bruising, bleeding in the bowels, blood in urine, low haemoglobin, and thrombocytopenia (low platelets). If any of these side effects persist or worsen, please consult your doctor.

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