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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Bipivac 0.5%Inj is used to reduce pain and discomfort during labour, surgery, dental treatment and other medical procedures. It contains Bupivacaine which works by blocking the transmission of pain signals and numbing the area. In some cases, this medicine may cause side effects such as weakness, numbness or tingling, restlessness, drowsiness, headache, nausea and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Whats That

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Synonym :

BUPIVACAINE HYDROCHLORIDE

Composition :

BUPIVACAINE-50MG

Manufacturer/Marketer :

Aesmira Lifesciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Bipivac 0.5%Inj

Bipivac 0.5%Inj belongs to the class of 'local anaesthetics', primarily used to reduce pain and discomfort during labour, surgery, dental treatment and other medical procedures. It produces local numbness and relieves pain. Bipivac 0.5%Inj is given in the form of an epidural injection at the spinal cord to prevent pain during labour and Caesarean section. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or intermittent. The tolerance level of pain might vary from person to person.

Bipivac 0.5%Inj contains 'Bupivacaine' that belongs to the group of medicines called 'amide-type anaesthetics'. Bupivacaine is a numbing medication that blocks the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus Bipivac 0.5%Inj helps in numbing the area and provides relief from pain.

Your doctor will decide the dose and duration based on the severity of your pain and response to treatment. Common side effects of Bipivac 0.5%Inj include weakness, numbness or tingling, restlessness, drowsiness, tremors or shakiness, headache, blurred vision, irregular heartbeat, chills or shivering, back pain, nausea and vomiting. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you have liver, kidney or heart diseases, high or low blood pressure, excess fat in the body and breathing problems before starting Bipivac 0.5%Inj. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother before using Bipivac 0.5%Inj. Bipivac 0.5%Inj causes drowsiness, so do not drive until you are mentally alert. Avoid alcohol to further prevent the worsening of side effects like drowsiness. Bipivac 0.5%Inj is not recommended for children less than one year of age.

Uses of Bipivac 0.5%Inj

Treatment of Temporary pain relief.

Directions for Use

Bipivac 0.5%Inj will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Bipivac 0.5%Inj contains 'Bupivacaine,' a local anaesthetic used to relieve pain and discomfort during labour, surgery, dental treatment and other medical procedures. It works by blocking the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus Bipivac 0.5%Inj helps in numbing the localized area and provides relief from pain. Bipivac 0.5%Inj, when injected as an epidural injection at the spinal cord, it prevents pain during labour and Caesarean section.

How Bipivac 0.5%Inj Works

Bipivac 0.5%Inj contains 'Bupivacaine' that belongs to the group of medicines called 'amide-type anaesthetics'. Bupivacaine is a numbing medication that blocks the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus Bipivac 0.5%Inj helps in numbing the area and provides relief from pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bipivac 0.5%Inj

  • Weakness
  • Numbness or tingling
  • Restlessness
  • Drowsiness
  • Tremors or shakiness
  • Headache
  • Blurred vision
  • Irregular heartbeat
  • Hypotension
  • Chills or shivering
  • Back pain
  • Nausea
  • Vomiting 

What if I have taken an overdose of Bipivac 0.5%Inj

Since Bipivac 0.5%Inj is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Brief your medical history to the doctor if you have any liver, kidney or heart diseases, high or low blood pressure, excess fat in the body, breathing problems, excess fluid in womb during pregnancy (a condition called hydramnios), a tumour of the ovary, blood poisoning (septicaemia) and fluid around lungs before starting Bipivac 0.5%Inj. Let your doctor know if you use any prescription and non-prescription medications, including vitamins and herbal supplements, before starting Bipivac 0.5%Inj. Bipivac 0.5%Inj may affect the foetus when used by a pregnant mother. It is also released into breast milk during breastfeeding. Please consult your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Bipivac 0.5%Inj causes dizziness and drowsiness, so do not drive until you are mentally alert. Avoid alcohol to prevent the worsening of side effects further. Bipivac 0.5%Inj is not recommended in children younger than one year of age.

Drug-Drug Interactions

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BupivacaineChloroquine
Severe
BupivacaineRasburicase
Severe

Drug-Drug Interactions

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BupivacaineChloroquine
Severe
How does the drug interact with Bipivac 0.5%Inj 20Ml:
Taking Bipivac 0.5%Inj 20Ml with chloroquine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Bipivac 0.5%Inj 20Ml and chloroquine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineRasburicase
Severe
How does the drug interact with Bipivac 0.5%Inj 20Ml:
Taking Bipivac 0.5%Inj 20Ml with rasburicase can increase the risk of methemoglobinemia(blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Bipivac 0.5%Inj 20Ml with Rasburicase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineIsosorbide dinitrate
Severe
How does the drug interact with Bipivac 0.5%Inj 20Ml:
Combining Bipivac 0.5%Inj 20Ml with Isosorbide dinitrate can increase the risk of methemoglobinemia(a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Bipivac 0.5%Inj 20Ml with Isosorbide dinitrate can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, confusion, consult a doctor right away. Do not stop using any medications without a doctor's advice.
BupivacaineRopivacaine
Severe
How does the drug interact with Bipivac 0.5%Inj 20Ml:
Combining Ropivacaine with Bipivac 0.5%Inj 20Ml can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
Although there is a possible interaction between Ropivacaine and Bipivac 0.5%Inj 20Ml, you can take these medicines together if prescribed by a doctor. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without consulting a doctor.
BupivacainePhenobarbital
Severe
How does the drug interact with Bipivac 0.5%Inj 20Ml:
Taking Bipivac 0.5%Inj 20Ml and Phenobarbital may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Bipivac 0.5%Inj 20Ml and phenobarbital together may cause an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineMetoclopramide
Severe
How does the drug interact with Bipivac 0.5%Inj 20Ml:
Coadministration of Bipivac 0.5%Inj 20Ml and Metoclopramide can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between metoclopramide and Bipivac 0.5%Inj 20Ml, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineNitric oxide
Severe
How does the drug interact with Bipivac 0.5%Inj 20Ml:
Taking Bipivac 0.5%Inj 20Ml and Nitric oxide may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Bipivac 0.5%Inj 20Ml and nitric oxide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineNitrofurantoin
Severe
How does the drug interact with Bipivac 0.5%Inj 20Ml:
Taking Bipivac 0.5%Inj 20Ml and Nitrofurantoin may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Taking Bipivac 0.5%Inj 20Ml and nitrofurantoin together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacainePhenazopyridine
Severe
How does the drug interact with Bipivac 0.5%Inj 20Ml:
Taking phenazopyridine with Bipivac 0.5%Inj 20Ml can increase the risk of methemoglobinemia,(a blood disorder that affects how red blood cells deliver oxygen throughout your body).

How to manage the interaction:
Although taking Bipivac 0.5%Inj 20Ml and phenazopyridine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineMepivacaine
Severe
How does the drug interact with Bipivac 0.5%Inj 20Ml:
Combining Bipivac 0.5%Inj 20Ml with Mepivacaine can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
Although taking Mepivacaine and Bipivac 0.5%Inj 20Ml together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the painful areas for 15-20 minutes regularly.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

LOCAL ANESTHETICS

Bipivac 0.5%Inj Substitute

Substitutes safety advice
  • Buloc 0.25 Injection 20 ml

    2.46per tablet
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Alcohol

Caution

You are recommended to limit or avoid alcohol consumption while taking Bipivac 0.5%Inj. Alcohol intake, along with Bipivac 0.5%Inj, may cause increased drowsiness.

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Pregnancy

Caution

Bipivac 0.5%Inj is a pregnancy category C drug. It may be unsafe to use during pregnancy since animal studies of Bipivac 0.5%Inj showed harmful effects on the foetus. Please consult your doctor before taking Bipivac 0.5%Inj if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Bipivac 0.5%Inj is excreted into the breast milk. Please consult your doctor before taking Bipivac 0.5%Inj if you are a nursing mother.

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Driving

Unsafe

Bipivac 0.5%Inj may make you feel dizzy and drowsy that can affect your ability to drive. Do not drive or operate machinery if you experience these side effects.

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Liver

Caution

Please consult your doctor since Bipivac 0.5%Inj should be used with caution in patients with liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor since Bipivac 0.5%Inj should be used with caution in patients with kidney impairment/kidney disease.

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Children

Caution

Bipivac 0.5%Inj is not recommended in children, unless prescribed by a doctor.

FAQs

Bipivac 0.5%Inj is used to induce anaesthesia to reduce pain and discomfort during labour, surgery, dental treatment and other medical procedures.
Bipivac 0.5%Inj temporarily blocks the pain signals from the nerves of the painful area to the brain, thereby causing numbness at the affected site and provides relief from pain.
Bipivac 0.5%Inj may affect your blood pressure. It is advised to inform your doctor before using Bipivac 0.5%Inj if you have high blood pressure during pregnancy or low blood pressure.
You are recommended to consult your doctor to know the after-effects of Bipivac 0.5%Inj if you are using an epidural injection of Bipivac 0.5%Inj. Some epidural numbing medications may have long-lasting or permanent effects on body functions like bowel movement or bladder control, sexual function and movement in your legs. Please discuss the risks and benefits thoroughly with your doctor.
After using Bipivac 0.5%Inj, you may not be able to move your body or the localized part for certain time. You may feel numbness in the injected area. When you are injected with an epidural, you may not be able to move your lower part of the body for a certain period. It is advised to stay careful during such times to avoid any injuries. After a dental procedure with the usage of Bipivac 0.5%Inj, please don't eat, chew gum or drink hot beverages until your mouth is completely free of numbness.
Bipivac 0.5%Inj should be used with caution and only under doctor's supervision if you have any liver, kidney or heart diseases, high or low blood pressure, excess fat in the body, breathing problems, excess fluid in womb during pregnancy (a condition called hydramnios), a tumour of the ovary, blood poisoning (septicaemia) and fluid around lungs. Please let your doctor know if you suffer from any medical issues before using Bipivac 0.5%Inj.
The common side effects of the Bipivac 0.5%Inj may include weakness, numbness or tingling, restlessness, drowsiness, tremors or shakiness, headache, blurred vision, chills or shivering, back pain, nausea, and vomiting. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
Bipivac 0.5%Inj contains Bupivacaine, which belongs to the group of medicines called amide-type anesthetics.
Pregnancy Category C means that animal studies have shown potential risks, but there are no good studies in pregnant women. As a result, the medication should only be used during pregnancy if the potential benefits justify the possible risks. Always consult your healthcare provider for personalized guidance.
Bipivac 0.5%Inj is not an opioid or narcotic. It belongs to the class of local anesthetics. It primarily reduces pain and discomfort during surgery, dental treatments, and other medical procedures.
Bipivac 0.5%Inj is a local anesthetic for numbing a specific area during surgeries or medical procedures. Depending on your condition, pain extent, and overall health, your doctor may combine it with other medications for optimal pain relief. Following your doctor's advice is best to avoid any potential interactions.
Both Ropivacaine and Bipivac 0.5%Inj are safe and effective local anesthetics. Your doctor will prescribe the one most suitable for you based on your health status and the severity of your condition.
Early signs of local anesthesia toxicity can include symptoms like perioral numbness (numbness around the mouth), tinnitus (ringing in the ears), agitation, difficulty speaking (dysarthria), and confusion. These may be followed by more severe central nervous system (CNS) derangements such as seizures and coma.

Country of origin

India

Manufacturer/Marketer address

C-3/6, Vasant Vihar, New Delhi - 110057
Other Info - BIP0021

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