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Bevaro 400 Injection 16 ml

Bevaro 400 Injection 16 ml

Prescription drug
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Manufacturer/Marketer

Cadila Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Bevaro 400 Injection

Bevaro 400 Injection is a monoclonal antibody used to treat metastatic breast cancer, non-small cell lung cancer, kidney cancer, cervical cancer, epithelial ovarian, fallopian tube, or primary peritoneal cancer, cancer of colon and rectum. Cancer is a condition where cells in a specific part of the body grow and reproduce uncontrollably. Cancer can start in one region of the body and spread to other parts. This is referred to as metastasis.

Bevaro 400 Injection contains 'Bevacizumab' that works against vascular endothelial growth factor (VEGF) which is found on the lining of lymph and blood vessels. VEGF causes blood vessels to grow within tumours which provide oxygen and nutrients to the tumour. Inhibition of vascular endothelial growth factor limits the flow of oxygen and nutrients to the tumour, causing it to shrink or cease developing. Thus, it helps treat cancers.

Bevaro 400 Injection will be administered by a healthcare professional; do not self-administer. Based on your medical condition, your doctor will decide the dose and duration. In some cases, Bevaro 400 Injection may cause loss of appetite, constipation, fever, nosebleeds, change in speech, and taste. The majority of these side effects do not require medical treatment and fade away with time. However, consult your doctor if the side effects persist or worsen

Avoid taking Bevaro 400 Injection if you are pregnant. Use effective contraception during the treatment and for 6months after the last dose. Bevaro 400 Injection may cause sleepiness and fainting, so avoid driving while on treatment with Bevaro 400 Injection. Do not breastfeed during the treatment and for 6months after the last dose of Bevaro 400 Injection. Keep your doctor informed about your health condition and all the medicines you take to rule out any side effects.

Uses of Bevaro 400 Injection

Treatment of Metastatic breast cancer, non-small cell lung cancer, kidney cancer, cervical cancer, epithelial ovarian, fallopian tube, or primary peritoneal cancer, cancer of colon and rectum

Medicinal Benefits

Bevaro 400 Injection contains Bevacizumab, a monoclonal antibody used to treat metastatic breast cancer, non-small cell lung cancer, kidney cancer, cervical cancer, epithelial ovarian, fallopian tube, or primary peritoneal cancer, cancer of colon and rectum. Bevaro 400 Injection works against a protein called vascular endothelial growth factor (VEGF). Vascular endothelial growth factor (VEGF) inhibition limits the flow of oxygen and nutrients to the tumour cells, causing them to shrink or cease developing. Thus, it helps treat cancer.

Directions for Use

Bevaro 400 Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bevaro 400 Injection

  • Constipation
  • Loss of appetite
  • Fever
  • Nose bleeds
  • Change in speech
  • Change in taste
  • Voice changes/hoarseness
  • Loss of body weight

Drug Warnings

Bevaro 400 Injection should only be taken under medical supervision. While taking Bevaro 400 Injection, the doctor will monitor your condition on a regular basis. If you have a history of allergic reactions to Bevaro 400 Injection or other medications, inform your doctor before taking it. Avoid taking Bevaro 400 Injection if you are pregnant. Use effective contraception during the treatment and for 6months after the last dose. Bevaro 400 Injection may cause sleepiness and fainting, so avoid driving while on treatment with Bevaro 400 Injection. Inform your doctor if you have/had high blood pressure, heart attack, stroke, bleeding problems, stomach/intestinal bleeding, perforation; if you had surgery in the past 28days/are due to have surgery. Do not breastfeed during the treatment and for 6months after the last dose of Bevaro 400 Injection. While taking Bevaro 400 Injection, please do not get any immunizations or vaccinations unless your doctor has approved it. Bevaro 400 Injection may increase the risk of bleeding, so be cautious and consult your doctor if you notice any bleeding or bruising.

Drug Interactions

Drug-Drug Interactions: Bevaro 400 Injection may have interaction with a drug used to treat renal and gastrointestinal cancer (sunitinib) and platinum or taxane-based therapies for lung or metastatic breast cancer. Inform your doctor if you have recently received, or are receiving, radiotherapy.

Drug-Food Interactions: Avoid the consumption of alcohol while taking Bevaro 400 Injection.

Drug-Disease Interactions: Inform your doctor if you have/had infections, bleeding disorders, fistula formation (an abnormal connection between two body parts), GI perforation, hypertension, PRES (Posterior Reversible Encephalopathy Syndrome), proteinuria (abnormal quantities of protein in the urine), and thromboembolic disorders.

Drug-Drug Interactions Checker List

  • SUNITINIB

Habit Forming

No

Diet & Lifestyle Advise

  • Meditating, reading novels, taking a nice bubble bath, or listening to calming music can all help you relax.
  • Yoga can also aid in the improvement of both physical and mental health.
  • Maintain a healthy weight by engaging in low-strain workouts on a regular basis and consuming nutritious foods.
  • To maintain a healthy weight, eat a portion of nutritious food and exercise on a regular basis.
  • Leafy greens, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs should all be part of your daily diet.
  • Rest well and get a good night's sleep.
  • Avoid smoking and consuming alcoholic beverages.
  • Fast food, fried foods, processed meats, refined carbohydrates, and added sugars should be avoided.

Special Advise

  • Your doctor may perform routine blood tests to evaluate your liver function, electrolyte levels, and blood cell count.
  • Peripheral blood counts should be closely maintained during the treatment and, if necessary, until recovery.
  • Wear protective clothing, sunglasses, and sunscreen to avoid unnecessary or prolonged exposure to sunlight and UV rays (such as tanning booths). Your skin may become sun-sensitive as a result of Bevaro 400 Injection.
  • Peripheral blood counts should be evaluated on a regular basis throughout Bevaro 400 Injection treatment and until full recovery is achieved.

Disease/Condition Glossary

Cancer: It is a condition where cells in a specific part of the body grow and reproduce uncontrollably. The cancerous cells can invade and destroy surrounding healthy tissue, including organs. Cancer sometimes begins in one part of the body and spreads to other areas. It occurs due to mutations in genes that regulate cell growth. The mutations cause the cells to divide and multiply in an uncontrolled manner, leading to tumour formation. The most common cancer treatment methods are surgery, chemotherapy, radiotherapy, bone marrow (stem cell) transplantation, immunotherapy, and targeted drug therapy.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Bevaro 400 Injection. It could lead to unpleasant side effects.

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Pregnancy

Unsafe

Bevaro 400 Injection should not be used during pregnancy because it causes harm to the fetus. Women of childbearing potential must use an effective contraception method while taking Bevaro 400 Injection and at least six months after the last dose. Please consult your doctor about any concerns regarding this.

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Breast Feeding

Unsafe

Avoid breastfeeding during treatment and for 6months after the last dose. This is due to the possibility of the medication being passed on to the infant through breast milk.

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Driving

Caution

Caution should be exercised when driving or operating machinery because in some cases, Bevaro 400 Injection may cause sleepiness and fainting.

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Liver

Caution

If you have/had a history of any liver-related diseases, please inform the doctor before taking Bevaro 400 Injection. Your doctor will weigh the benefits and potential risks before prescribing Bevaro 400 Injection.

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Kidney

Caution

If you have/had a history of any kidney-related diseases, please inform the doctor before taking Bevaro 400 Injection. Your doctor will weigh the benefits and potential risks before prescribing Bevaro 400 Injection.

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Children

Unsafe

Bevaro 400 Injection is not recommended for children below 18years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, India.
Other Info - BEV0040

Author Details

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FAQs

Bevaro 400 Injection is a monoclonal antibody used to treat metastatic breast cancer, non-small cell lung cancer, kidney cancer, cervical cancer, epithelial ovarian, fallopian tube, or primary peritoneal cancer, cancer of colon and rectum.
Bevaro 400 Injection works against a protein called vascular endothelial growth factor (VEGF). Inhibition of vascular endothelial growth factor (VEGF) limits the flow of oxygen and nutrients to the tumour cells, causing them to shrink or cease developing. Thereby, Bevaro 400 Injection helps treat cancer.
Bevaro 400 Injection may reduce the number of red blood cells leading to anaemia. Its symptoms include pale skin, lack of energy, feeling breathless, feeling dizzy and lightheadedness.
Chemotherapy remains necessary. Bevaro 400 Injection is given along with chemotherapy for treating cancer.
Bevaro 400 Injection may increase the risk of bleeding and problems with wound healing. If you have had major surgery in the past 28days or if the wound hasn't healed, you should not take Bevaro 400 Injection. Talk to your doctor for more information.
Cancer can affect anyone, though the risk increases with age. Individual risk is determined by factors such as smoking and drinking habits, lifestyle choices such as what you eat and exercise; a family history of cancer, and factors in your workplace and environment.
Bevaro 400 Injection may increase the incidence of hypertension. Therefore, consult your doctor before taking Bevaro 400 Injection if you have high blood pressure.

Disclaimer

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Keep Refrigerated. Do not freeze.

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