Bestofix DM Tablet is used to reduce the pain of osteoarthritis (OA). Osteoarthritis is a chronic (lifelong) joint condition in which glucosamine sulfate (a chemical found in the human body, especially in joints) gets reduced. When this chemical gets reduced, the cartilage breaks down and becomes thin, which causes friction between the bones, leading to wear and tear (damage) of the joint tissues. Symptoms include pain, stiffness, inflammation of the joints, and reduced locomotion.

Bestofix DM Tablet contains Diacerein, Dimethyl sulfoxide, and Glucosamine. Diacerein slows down the breakdown of cartilage and helps to reduce pain and swelling. Dimethyl sulfoxide reduces the inflammation of the joints. Glucosamine reduces the breakdown of cartilage and helps to repair joints. Together, Bestofix DM Tablet can lower pain, swelling, and inflammation of the joints.

You should take this medicine as your doctor has instructed. The common side-effects of Bestofix DM Tablet are headache, tiredness, nausea, abdominal pain, indigestion, onion-like taste in the mouth, diarrhoea, discolouration of the urine, constipation, and wind (flatulence). These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Bestofix DM Tablet if you are allergic to any of its contents, shellfish, or soya. Before taking Bestofix DM Tablet , inform your doctor if you have glucose intolerance, liver or kidney disease, high cholesterol, asthma, bladder or kidney cancer, and vision problems. It is not recommended for use in children, pregnant women, and breastfeeding mothers. It should be used with caution in the elderly. Avoid alcohol consumption as it may increase the risk of side effects. Bestofix DM Tablet may decrease alertness, so do not drive or operate heavy machinery if you are not fully alert.

Bestofix DM Tablet improves joint's movement and flexibility by helping in the formation of cartilage (the soft tissue that cushions the joints) and lubricating the joints. It helps to repair joints and slow down the progression of the disease. It helps to relieve pain, swelling, and inflammation of the joints. Pain relief and improved motility can help you to perform daily activities easily.

• Headache
• Tiredness
• Nausea
• Abdominal pain
• Indigestion
• Onion-like taste in the mouth
• Diarrhea
• Discoloration of the urine
• Constipation
• Wind (flatulence)

Bestofix DM Tablet may cause high cholesterol, so it should be used with caution in patients with heart disease risk. Bestofix DM Tablet may worsen the symptoms of asthma. You may notice discoloration of urine and an onion-like taste in the mouth. However, these effects are mild and do not require medical attention. If you notice any changes in vision while using Bestofix DM Tablet , inform your doctor immediately as this medicine may increase pressure in the eye.

Drug-Drug Interactions: Bestofix DM Tablet may interact with a blood thinner (warfarin), antidiabetic medicines (metformin, glimepiride, and glibenclamide, etc.), and antibiotic (tetracycline).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Bestofix DM Tablet should be used with caution in patients with glucose intolerance, liver or kidney disease, high cholesterol, asthma, bladder or kidney cancer, and vision problems.

• WARFARIN
• METFORMIN
• GLIBENCLAMIDE
• GLIMEPIRIDE
• TETRACYCLINE

• Include more glucosamine, chondroitin sulfate, vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

• Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.

• In the chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.

• Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit little as possible, and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

• Your doctor may advise you to regularly monitor blood glucose levels while using Bestofix DM Tablet .  
• Patients taking anticoagulant therapy should be carefully monitored during the treatment with Bestofix DM Tablet .

Osteoarthritis: Osteoarthritis is a chronic (lifelong) joint condition in which glucosamine sulfate (a chemical found in the human body, especially in joints) gets reduced. The body uses this fluid to produce other chemicals required to make ligaments, cartilage, tendons, and the thick fluid surrounding joints. When this chemical gets reduced, the cartilage breaks down. It becomes thin, which causes friction between the bones, leading to wear and tear (damage) of the joint tissues, leading to pain, stiffness, inflammation, and reduced locomotion.  It causes the bone to rub together, leading to pain, stiffness, and other osteoarthritis symptoms. This disease can occur in any joint, but commonly affected areas of the body are hands, fingertips, knees, hips, spine, typically at the neck or lower back. The most common symptoms of osteoarthritis include pain, tenderness (discomfort when pressing on the area with fingers), stiffness, and inflammation.