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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST
Azawan Tablet helps to reduce the pain/inflammation in rheumatoid arthritis conditions and keep the immune system from attacking new transplant organs like kidneys. Besides this, it also treats pain and inflammation in gastrointestinal issues like Crohn's disease, and ulcerative colitis, for patients who have undergone a kidney transplant. It contains Azathioprine, which works by reducing the function of the cells, causing inflammation, especially in the joint tissues thereby decreasing pain, inflammation, and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. This medicine helps stop your body from rejecting a new organ by suppressing your immune system. In some cases, you may experience certain common side effects such as nausea, headaches, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, lowered resistance to infections, tingling sensation, stomach pain, leukopenia (decreased number of white blood cells), and sore throat.
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Manufacturer/Marketer

Rowan Bioceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Azawan Tablet

Azawan Tablet is used to reduce the pain/inflammation in rheumatoid arthritis conditions and keep the immune system from attacking new transplant organs like kidneys. Besides this, it also treats pain and inflammation in gastrointestinal issues like Crohn's disease and ulcerative colitis for patients who have undergone a kidney transplant. 

Azawan Tablet contains 'Azathioprine' that works by reducing the function of the cells, causing inflammation, especially in the joint tissues, thereby decreasing pain and inflammation and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Azawan Tablet helps stop your body from rejecting a new organ by suppressing your immune system. 

Take Azawan Tablet as prescribed. Your doctor will advise you on how often you take Azawan Tablet based on your medical condition. In some cases, you may experience certain common side-effects such as nausea, headaches, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, increase in liver enzymes, lowered resistance to infections, tingling sensation, stomach pain, leukopenia (decreased number of white blood cells), and sore throat. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Azawan Tablet for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Azawan Tablet if you are pregnant or planning for pregnancy. Azawan Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Azawan Tablet should not be given to children as safety and efficacy have not been established. Azawan Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using Azawan Tablet. While taking Azawan Tablet, do not contact anyone who has shingles, chickenpox, or measles. If you accidentally come in contact with any person who has them, please inform your doctor immediately, as special treatment is required if you have not had these illnesses. Your doctor may advise you to undergo regular blood tests and kidney and liver tests to monitor your condition. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Uses of Azawan Tablet

Treatment of Rheumatoid arthritis, Immunosuppressant therapy after kidney transplant.

Medicinal Benefits

Azawan Tablet contains 'Azathioprine', which is an immunosuppressant that works by reducing the function of the cells and causing inflammation in the joint tissues. It reduces pain and inflammation and slows joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Azawan Tablet helps stop your body from rejecting a new organ by suppressing your immune system. Azawan Tablet is also used to treat severe inflammatory diseases of the skin, Crohn's disease, ulcerative colitis, and some blood disorders.

Directions for Use

Swallow Azawan Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Azawan Tablet

  • Nausea
  • Headaches
  • Vomiting
  • Diarrhoea
  • Unusual fatigue
  • Dizziness
  • Headache
  • Loss of appetite
  • Increase in liver enzymes
  • Lowered resistance to infections
  • Tingling sensation
  • Stomach pain
  • Leukopenia (decreased number of white blood cells)
  • Sore throat

Drug Warnings

Do not take Azawan Tablet if you are allergic to any immunosuppressant medicines or Azathioprine. Let your doctor know before using Azawan Tablet if you have liver or kidney problems, serious blood disorders, immune system problems, bone marrow problems, serious infections, immunodeficiency syndrome, or if you have a condition where your body produces too little of a natural chemical called thiopurine methyltransferase (TPMT), received any vaccinations. Do not take Azawan Tablet if you are pregnant or planning for pregnancy as Azawan Tablet is a Pregnancy category risk D medicines which can cause serious congenital disabilities to the unborn baby. Azawan Tablet should not be taken by breastfeeding mothers as it passes into breast milk. While taking Azawan Tablet, do not contact anyone who has shingles, chickenpox, or measles. If you accidentally come in contact with any person having them, please inform your doctor immediately as it requires special treatment if you have not had these illnesses. Azawan Tablet causes dizziness and drowsiness, so drive with caution. Azawan Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Azawan Tablet as it could lead to increased dizziness. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Using Azawan Tablet for a long time can increase your chance of getting certain types of cancer, such as lymphoma (cancer of the spleen, thymus gland, and bone marrow), leukemia (blood cancer), and skin cancer. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using Azawan Tablet.

Drug Interactions

Drug-Drug Interaction: Azawan Tablet may have interaction with other immunosuppressant medicines (tacrolimus), anti-gout (allopurinol, oxypurinol, thiopurine), angiotensin-converting enzyme (ACE) inhibitors (benazepril, captopril, enalapril, fosinopril, moexipril, perindopril, quinapril, ramipril), blood thinner (warfarin, phenprocoumon), medicines used to treat inflammation of the bowels (infliximab), medicines used to treat ulcers (cimetidine, olsalazine, mesalazine, sulfasalazine), diuretics (furosemide), medicines used to treat bacterial infections (trimethoprim, sulfamethoxazole), pain killers (indomethacin), medicines used as muscle relaxants (d-tubocurarine, pancuronium, succinylcholine).

Drug-Food Interaction:  Avoid alcohol consumption while taking Azawan Tablet as it may increase dizziness.

Drug-Disease Interaction: Azawan Tablet may cause interactions with disease conditions such as leukopenia (low levels of white blood cells), infections, have any unusual bleeding or bruising liver, and kidney dysfunction.

Drug-Drug Interactions Checker List

  • TACROLIMUS
  • ALLOPURINOL
  • BENAZEPRIL
  • CAPTOPRIL
  • ENALAPRIL
  • FOSINOPRIL
  • LISINOPRIL
  • PERINDOPRIL
  • RAMIPRIL
  • WARFARIN
  • PHENPROCOUMON
  • INFLIXIMAB
  • CIMETIDINE
  • MESALAZINE
  • SULFASALAZINE
  • FUROSEMIDE
  • TRIMETHOPRIM+SULFAMETHOXAZOLE
  • INDOMETHACIN
  • TUBOCURARINE
  • PANCURONIUM
  • SUCCINYLCHOLINE

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.

  • Acupuncture, massage, and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

  • Avoid smoking and alcohol consumption.

 

Special Advise

  • Use sunscreen while taking Azawan Tablet, as it can make your skin more sensitive to sunlight and may cause skin cancer.

  • Long-term use of Azawan Tablet may increase your risk of developing cancers like blood cancer, skin cancer and immune system cancer (lymphoma). 

Disease/Condition Glossary

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.

Kidney transplant rejection: When you get a new kidney transplanted to your body, your body recognizes it as a foreign element and tries to attack, and reject it because it is not originally part of your body. So, immunosuppressant drugs like Azathioprine are given to such patients to suppress their immune system to attack a newly transplanted kidney. The ultimate goal is to adjust immunosuppressants to prevent rejection and minimize any side effects of the drugs.

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Azawan Tablet. It could lead to increased dizziness and drowsiness.

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Pregnancy

Caution

Azawan Tablet is a Category D pregnancy drug that is not recommended for pregnant women or given only when strictly guidance of the doctor as there is no clinical data available on use in pregnant women.

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Breast Feeding

Caution

It is not recommended to take Azawan Tablet while you are breastfeeding. Azawan Tablet passes into breast milk.

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Driving

Caution

Azawan Tablet may cause dizziness, drowsiness, and tiredness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Take Azawan Tablet only after the doctor's prescription, especially if you are dealing with Liver diseases/conditions as your doctor may adjust the dose as required.

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Azawan Tablet.

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Children

Unsafe

Azawan Tablet should not be used by children below 18 years of age, as the efficacy and safety have not been established.

Country of origin

India
Other Info - AZ28985

Author Details

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FAQs

Azawan Tablet is used in treating Rheumatoid arthritis and immunosuppressant therapy after kidney transplant.
Azawan Tablet causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.
Azawan Tablet acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby provides relief from rheumatoid arthritis.
If you miss a dose of Azawan Tablet, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
Diarrhoea might be a side-effect of Azawan Tablet. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
Azawan Tablet is a Category D pregnancy drug that is not recommended for pregnant women or given only when strictly guidance of the doctor as there is no clinical data available on use in pregnant women.
Azawan Tablet starts to work gradually. it can take up to 12 weeks of taking the right adjusted dose before you notice any benefits.
If you miss a prescription dose, take it as soon as you recall and resume your regular routine. If you are near the next dose, skip the missing dose and resume your regular schedule. Do not take a double dose to make up for a forgotten dose.
It depends on your individual medical condition and response to the medication. Your doctor will determine the appropriate duration of treatment based on your specific needs.
Taking Azawan Tablet for a long time can increase your risk of developing some types of cancer, including skin cancer. As a result, avoid direct sunlight, apply sunscreen (SPF 30 or higher), and wear in clothes that shield your arms and legs.
You'll have regular blood tests while taking azathioprine. These tests will ensure that any concerns or problems are found quickly.
Azawan Tablet may have an effect on your liver, kidneys, or bone marrow. Before you begin taking this medication, you will undergo blood tests to assess your liver function, renal function, and blood count. From week one to week eight of your treatment, you will undergo at least one blood test every week.
Yes, taking Azawan Tablet for a long time can increase your risk of developing some types of cancer, including skin cancer. Seek medical attention if you experience any changes in your body.
Using Cyclosporine together with Azawan Tablet may decrease the effects of cyclosporine. Caution is advised if Cyclosporine must be taken with Azawan Tablet. You may need a dose adjustment or special test if you use both medications.
Alcohol does not affect the way azathioprine works. However, both azathioprine and alcohol can affect your liver. For this reason, limit or avoid the consumption of alcohol is recommended.
Common side effects of Azawan Tablet may include nausea, headaches, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, increase in liver enzymes, lowered resistance to infections, tingling sensation, stomach pain, leukopenia (decreased number of white blood cells), and sore throat. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

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