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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 9, 2024 | 12:37 PM IST
Axonrich Tablet is a combination medicine used to manage neuropathic pain due to damaged nerves. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps alter the nerve signals that are responsible for pain and also provides a protective effect on the nerve tissues and the brain. You may experience common side effects like dizziness, sleepiness, tiredness, nausea, and vomiting.
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About Axonrich Tablet

Axonrich Tablet is indicated for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms of neuropathic pain include burning or shooting pain followed by tingling and numbness (loss of sensation). Neuropathic pain can be caused due to amputation of limbs, diabetic neuropathy (nerve damage due to excess blood sugar level), excessive alcohol intake (alcoholism), and cancer treatment via chemotherapy.

Axonrich Tablet is a combination of five drugs: Pregabalin, Mecobalamin, Alpha-lipoic acid, Pyridoxine-5-phosphate, and Calcium-L-5-Methyltetrahydrofolate. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Mecobalamin and Pyridoxine-5-phosphate help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and the brain. Calcium-L-5-Methyltetrahydrofolate helps in delivering essential nutrients to the nerves. Together, Axonrich Tablet provides relief from neuropathic pain.

Use Axonrich Tablet as suggested by your doctor. In some cases, you may experience certain common side-effects, such as dizziness, sleepiness, tiredness, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before starting Axonrich Tablet if you are pregnant or breastfeeding. Axonrich Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Axonrich Tablet as it could lead to increased dizziness and sleepiness. Axonrich Tablet is not recommended for children as safety and effectiveness have not been established. Let your doctor know if you are taking any other medicines, including vitamins and herbal supplements.

Uses of Axonrich Tablet

Treatment of Neuropathic pain

Medicinal Benefits

Axonrich Tablet contains Pregabalin (anti-convulsant or antiepileptic), Mecobalamin (vitamin B12), Alpha-lipoic acid (antioxidant), Pyridoxine-5-phosphate (vitamin B6), and Calcium-L-5-Methyltetrahydrofolate. Axonrich Tablet is used to treat neuropathic pain. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Mecobalamin and Pyridoxine-5-phosphate help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Calcium-L-5-Methyltetrahydrofolate helps in providing essential nutrients to the nerves. Together, Axonrich Tablet helps in providing relief from neuropathic pain.

Directions for Use

Swallow it as a whole with a glass of water; do not chew, crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Axonrich Tablet

  • Dizziness
  • Sleepiness
  • Tiredness
  • Nausea
  • Vomiting

Drug Warnings

Do not take Axonrich Tablet if you are allergic to any of its contents. Inform your doctor before taking Axonrich Tablet if you have/had heart problems or bipolar syndrome. Please do not stop taking Axonrich Tablet without consulting your doctor as it could cause withdrawal symptoms. Do not take Axonrich Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Axonrich Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Axonrich Tablet as it could lead to increased dizziness and sleepiness. Axonrich Tablet is not recommended for children as safety and effectiveness have not been established. Consult your doctor immediately if you experience suicidal tendencies.

Drug Interactions

Drug-Drug Interaction: Axonrich Tablet may have interaction with antidepressants (amitriptyline), pain killer (codeine, tramadol), anti-convulsant (gabapentin), anti-anxiety (diazepam), anti-diabetic (metformin), immunosuppressant (methotrexate), anti-rheumatoid (sulfasalazine), antibiotic (chloramphenicol), anti-cancer (altretamine), and anti-Parkinson’s (levodopa).

Drug-Food Interaction: Avoid consumption of alcohol while taking Axonrich Tablet as it might cause increased dizziness and sleepiness.

Drug-Disease Interaction: Axonrich Tablet may have interactions with disease conditions such as angioedema, creatine kinase elevations, peripheral oedema, malabsorption, and anaemia.

Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • CODEINE
  • TRAMADOL
  • GABAPENTIN
  • DIAZEPAM
  • METFORMIN
  • METHOTREXATE
  • SULFASALAZINE
  • CHLORAMPHENICOL
  • ALTRETAMINE
  • LEVODOPA

Habit Forming

No

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

Disease/Condition Glossary

Neuropathic pain: It is a nervous disorder that occurs due to nerve damage caused by chronic progressive nerve disease, limb amputation, diabetes, or due to infection or injury. The pain could be intermittent or continuous, felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of senses is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain that is not triggered by an injury, the body sends the pain signals unpromptedly. Symptoms include spontaneous, un-triggered pain, unpleasant feeling, shooting, burning, or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Axonrich Tablet as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Avoid taking Axonrich Tablet if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Axonrich Tablet ; your doctor will decide whether Axonrich Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Axonrich Tablet may cause drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Axonrich Tablet is not recommended for children as safety and efficacy have not been established.

Country of origin

INDIA

Manufacturer/Marketer address

Primus Remedies Pvt Ltd, C-16, Ankur Cooperative Society, Thakurli Estate, Dombivili, Mumbai-421202.
Other Info - AXO0073

Author Details

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FAQs

Axonrich Tablet is indicated for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system.
Axonrich Tablet contains pregabalin, mecobalamin, alpha-lipoic acid, pyridoxine-5-phosphate, and calcium-L-5-methyltetrahydrofolate. It affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Axonrich Tablet also helps reduce further nerve damage in neuropathy. It works by improving blood circulation to peripheral body parts and thus relieving pain.
To treat your condition effectually, continue taking Axonrich Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Axonrich Tablet ; your doctor will reduce the dose gradually.
If you miss a dose, take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose. Avoid taking a double dose.

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