Axinerve-GB Ointment is a combination medicine used to relieve neuropathic pain. It helps in treating chronic pain caused due to nerve damage in diabetes, shingles, and spinal cord injury. Neuropathic pain is a nervous system disorder caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury.

Axinerve-GB Ointment consists of four drugs: Capsaicin, Gabapentin, Ketoprofen, and Methyl salicylate. Capsaicin is a natural extract of chili pepper that works by blocking the pain messengers to the nerves. Gabapentin is an anti-epileptic agent that alters the way the nerves send messages to the brain, thus relieving pain. Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical substances, such as prostaglandins and leukotrienes, that cause pain and swelling. Methyl salicylate is a topical rubefacient that temporarily relieves muscle or joint pain caused by strains and sprains.

Axinerve-GB Ointment is for external use only. Take a pea-sized amount onto your fingers and apply it to the affected areas. You are advised to use Axinerve-GB Ointment for as long as your doctor has prescribed it for you, depending on your medical condition. Sometimes, you may experience certain common side-effects such as application site reactions like itching, irritation, redness, and burning sensation. These side-effects do not require medical attention and will resolve gradually over time. However, if these side effects persist for a longer time, please see your doctor. 

Do not use Axinerve-GB Ointment if you have had any recent heart surgery as Axinerve-GB Ointment can increase your risk of fatal heart attack or stroke. Axinerve-GB Ointment may increase the chances of stomach ulcers and bleed. Do not take Axinerve-GB Ointment if you are pregnant or breastfeeding unless prescribed. Axinerve-GB Ointment is not recommended for children as safety and efficacy have not been established. Avoid or limit exposure to natural or artificial sunlight as Axinerve-GB Ointment may cause a burning sensation. Do not take any other NSAIDs for pain relief along with Axinerve-GB Ointment unless prescribed.

Axinerve-GB Ointment is used to treat neuropathic pain caused due to nerve damage in diabetes, shingles, and spinal cord injury. It contains Capsaicin, Gabapentin, Ketoprofen, and Methyl salicylate. Capsaicin is a natural extract of chili pepper that works by blocking the pain messengers to the nerves. Gabapentin is an anti-epileptic agent that alters the way the nerves send messages to the brain, thus relieving pain. Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical substances, such as prostaglandins and leukotrienes, that cause pain and swelling. Methyl salicylate is a topical rubefacient that temporarily relieves muscle or joint pain caused by strains and sprains. Together, Axinerve-GB Ointment helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

• Itching
• Irritation
• Redness
• Burning sensation

Do not take Axinerve-GB Ointment if you are allergic to any of its contents. If you have/had severe heart problems, stomach ulcer or perforation, and bleeding problems, bypass surgery, heart attack, blood circulation problems, or inflammation of intestines, please inform your doctor in advance. Inform your doctor before using Axinerve-GB Ointment if you are taking any other NSAID/pain killers orally. Do not use Axinerve-GB Ointment if you are pregnant or breastfeeding unless prescribed. Axinerve-GB Ointment is not recommended for children as safety and effectiveness have not been established. Do not take any other NSAIDs for pain relief along with Axinerve-GB Ointment unless prescribed.

Drug-Drug Interaction: Axinerve-GB Ointment may interact with blood thinners (anisindione, dicumarol, warfarin), pain killers (hydrocodone, acetaminophen), antidepressants (duloxetine, escitalopram, sertraline), muscle relaxants (cyclobenzaprine), anti-anxiety drugs (alprazolam), fits medicines (pregabalin), antipsychotics (quetiapine), steroids (prednisone), antidepressants (lithium), anti-cancer drugs (methotrexate), gout medicines (probenecid), and water pills.

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: Inform your doctor before starting Axinerve-GB Ointment if you have/had heart problems, stomach ulcers or perforation, and bleeding problems, bypass surgery, heart attack, blood circulation problems, or inflammation of intestines.

• ANISINDIONE
• WARFARIN
• DICUMAROL
• HYDROCODONE
• ACETAMINOPHEN
• DULOXETINE
• ESCITALOPRAM
• SERTRALINE
• CYCLOBENZAPRINE
• ALPRAZOLAM
• PREGABALIN
• QUETIAPINE
• PREDNISONE
• LITHIUM
• METHOTREXATE
• PROBENECID

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
• Follow heat or cold therapy; apply a cold or hot compress on the joints for 15-20 minutes.
• De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
• Acupuncture, massage, and physical therapy may also be helpful.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
• Avoid smoking and alcohol consumption.
• Using essential oils for massages can help increase circulation and boosts healing.

• If Axinerve-GB Ointment comes in contact with eyes, nose, or mouth, rinse with water immediately.
• Wash your hands before and after using Axinerve-GB Ointment; however, do not wash your hands if you apply Axinerve-GB Ointment on your hands.

Neuropathic pain: It is a nervous system disorder caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).