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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:07 PM IST
Axepine MD 5 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines. It contains Aripiprazole, which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbelief, and unfriendly characteristics of schizophrenia. It improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, it improves mood swings, depression, and other psychotic problems. Some people may experience drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production.
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Prescription drug

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Composition

ARIPIPRAZOLE-5MG

Manufacturer/Marketer

Cnx Health Care Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Axepine MD 5 Tablet

Axepine MD 5 Tablet is an antipsychotic medicine used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Axepine MD 5 Tablet also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterized by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused by disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Axepine MD 5 Tablet contains Aripiprazole, which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing its overactivity, thereby controlling the positive symptoms like hallucinations, misbelief, and unfriendly characteristics of schizophrenia. Axepine MD 5 Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Axepine MD 5 Tablet improves mood swings, depression, and other psychotic problems. 

Take Axepine MD 5 Tablet as prescribed. Your doctor will advise you how often you take Axepine MD 5 Tablet based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Axepine MD 5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Axepine MD 5 Tablet or any other medicines, please tell your doctor. Axepine MD 5 Tablet should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions such as dizziness, inability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Axepine MD 5 Tablet if you are pregnant or breastfeeding, and consult a doctor. Axepine MD 5 Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behaviour while taking Axepine MD 5 Tablet , please contact a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements, especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Axepine MD 5 Tablet .

Uses of Axepine MD 5 Tablet

Treatment of Schizophrenia, Mania, Bipolar disorder, and irritability associated with an autism spectrum disorder

Medicinal Benefits

Axepine MD 5 Tablet contains Aripiprazole, which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Axepine MD 5 Tablet inhibits the dopamine receptor in our brain, thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Axepine MD 5 Tablet improves overall behaviour and thoughts and helps people have a better social life and comfortably do daily activities. Axepine MD 5 Tablet may be used in combination with other medicines to treat depression. Additionally, Axepine MD 5 Tablet is also used to reduce the severity of unwanted sounds (tics) in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements).

Directions for Use

Tablet: Take it with or without food as advised by the doctor, and swallow it as a whole with a glass of water. Do not crush, chew or break it. Oral solution: Shake the bottle well before use and take it as advised by the doctor. Take it with the help of a measuring cup that is provided with the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Axepine MD 5 Tablet

  • Drowsiness

  • Headache

  • Tiredness

  • Akathisia (inability to sit still)

  • Difficulty in sleeping

  • Light-headedness

  • Indigestion

  • Shaking

  • Blurred vision

  • Nausea

  • Vomiting

  • Anxiety

  • Increased saliva production

Drug Warnings

If you are allergic to Axepine MD 5 Tablet or any other medicines, please tell your doctor. Axepine MD 5 Tablet should be used with caution in elderly patients above 65 years of age as there is an increased risk of adverse reactions such as dizziness, changes in the ability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Axepine MD 5 Tablet if you are pregnant or breastfeeding and consult a doctor. Axepine MD 5 Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Axepine MD 5 Tablet , please contact a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or are advised to stop taking Axepine MD 5 Tablet . If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Axepine MD 5 Tablet .

Drug Interactions

Drug-Drug Interaction: Axepine MD 5 Tablet may have interaction with medicines used to lower high blood pressure (metoprolol), antipsychotics (olanzapine), antidepressants (fluoxetine, paroxetine, venlafaxine), antifungals (itraconazole, ketoconazole), medicines used to treat irregular heartbeat (amiodarone, flecainide, quinidine), HIV drugs (nevirapine, efavirenz, indinavir, ritonavir), painkillers (ibuprofen), antibiotics (rifampicin, rifabutin), anticonvulsants (phenytoin, carbamazepine, phenobarbital).

Drug-Food Interaction: Axepine MD 5 Tablet may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Axepine MD 5 Tablet as it may reduce the effect of Axepine MD 5 Tablet . Avoid taking St. John's Wort (herbal medicine used to treat depression) as it may interact with Axepine MD 5 Tablet . Also, avoid alcohol intake as it may increase side effects such as drowsiness, dizziness or difficulty in concentrating.

Drug-Disease Interaction: If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, liver or kidney problems, inform your doctor before taking Axepine MD 5 Tablet .

Drug-Drug Interactions Checker List

  • METOPROLOL
  • OLANZAPINE
  • FLUOXETINE
  • PAROXETINE
  • VENLAFAXINE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • AMIODARONE
  • FLECAINIDE
  • QUINIDINE
  • NEVIRAPINE
  • EFAVIRENZ
  • INDINAVIR
  • RITONAVIR
  • IBUPROFEN
  • RIFAMPICIN
  • RIFABUTIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Habit Forming

No

Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Axepine MD 5 Tablet .

  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards and herring.

  • Cut down sugars, salt and saturated fats.

  • Drink adequate water to keep the body hydrated.

  • Do regular exercise and maintain a stable weight as Axepine MD 5 Tablet may cause weight gain.

  • Avoid consumption of alcohol as it may increase drowsiness.

Special Advise

  • Elderly patients more than 65 years with dementia-related psychosis treated with Axepine MD 5 Tablet can be at an increased risk of death. 

  • Axepine MD 5 Tablet is not prescribed and approved for the treatment of dementia-related psychosis. 

  • Increased risk of suicidal thinking and behavior changes has been observed in children, adolescents, and young adults taking Axepine MD 5 Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.  

Disease/Condition Glossary

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or sleep pattern changes, high levels of stress, and alcohol intake. Seek medical help immediately if you have any self-harming or suicidal thoughts.

Bipolar disorder: It is also called manic depression, associated with extreme mood swings ranging from manic highs to depressive lows. The symptoms of bipolar disorder include mania (high energy and excitability) and depression (loss of interest, hopelessness, low energy). Bipolar disorder involves lifelong treatment. 

Depression: It is a mental condition characterized by low mood and a loss of interest in activities. People affected by this condition are often unsocial and try to keep isolated from other social activities. 

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Axepine MD 5 Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty in concentrating.

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Pregnancy

Unsafe

Axepine MD 5 Tablet is a Category C pregnancy drug and is not recommended for use during pregnancy, especially in the third trimester as it may cause adverse effects in the newborn baby. Axepine MD 5 Tablet may cause extrapyramidal and/or withdrawal symptoms in newborn babies with third-trimester exposure.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Axepine MD 5 Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Axepine MD 5 Tablet may cause dizziness or vision problems such as blurred vision. Therefore, avoid driving if you feel dizzy or have vision disturbances after taking Axepine MD 5 Tablet .

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Liver

Caution

Take Axepine MD 5 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Axepine MD 5 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Axepine MD 5 Tablet is not recommended for children below 15 years due to the increased risk of adverse effects. However, please consult a doctor before giving Axepine MD 5 Tablet to children.

Country of origin

India

Manufacturer/Marketer address

1 A, PATANWALA INDUSTRTIAL COMPOUND, LBS ROAD, NEAR SHREYAS CINEMA, GHATKOPAR-W, MUMBAI-400 086
Other Info - AXE0172

Author Details

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FAQs

Axepine MD 5 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines.
Axepine MD 5 Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and prevents its overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbelief and unfriendliness) of schizophrenia. Also, Axepine MD 5 Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Thereby, Axepine MD 5 Tablet improves behaviour, thoughts and helps in having a better social life and enables to comfortably do daily activities.
No, you are not recommended to take Axepine MD 5 Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Axepine MD 5 Tablet in the blood leading to increased adverse effects. However, please consult a doctor before taking Axepine MD 5 Tablet with other medicines.
Axepine MD 5 Tablet may cause weight gain in some patients but it is not necessary for everyone taking Axepine MD 5 Tablet to experience this side effect. However, in order to avoid gaining weight while taking Axepine MD 5 Tablet , you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.
Axepine MD 5 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people as it may cause severe adverse effects including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Axepine MD 5 Tablet .
Yes, Axepine MD 5 Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Axepine MD 5 Tablet and inform your doctor if you have diabetes before taking Axepine MD 5 Tablet . However, if you experience dry mouth, increased thirst or urination, fruity breath odour, please consult a doctor as these might be signs of high blood sugar.
No, you are not recommended to stop taking Axepine MD 5 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Axepine MD 5 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Axepine MD 5 Tablet , please consult your doctor so that the dose may be gradually reduced.
Yes, Axepine MD 5 Tablet is a mood stabilizer. It helps calm the mood and treats mood-related problems.
Axepine MD 5 Tablet might start working within a few days or weeks. However, you may notice the full benefits of Axepine MD 5 Tablet after 2-3 months. Continue taking Axepine MD 5 Tablet for the prescribed duration to prevent the recurrence of symptoms.
Axepine MD 5 Tablet may cause priapism (prolonged and painful erection) in some people. Please consult the doctor if you have any concerns.
Elderly patients more than 65 years old with dementia-related psychosis treated with Axepine MD 5 Tablet can be at an increased risk of death. Increased risk of suicidal thinking and behaviour changes has been observed in children, adolescents, and young adults taking Axepine MD 5 Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.
Avoid intake of grapefruit juice with Axepine MD 5 Tablet as it may reduce the effect of Axepine MD 5 Tablet . Also, avoid alcohol consumption with Axepine MD 5 Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty in concentrating. Do not drive if you feel dizzy or have vision disturbances after taking Axepine MD 5 Tablet .
Consult the doctor if you are diabetic as Axepine MD 5 Tablet may cause high blood sugar levels. Regular monitoring of blood glucose levels is advised.
Axepine MD 5 Tablet may cause side effects like drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Axepine MD 5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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