Augplat 500 mcg Injection belongs to the class of 'platelet-stimulating agents' primarily used to treat chronic immune thrombocytopenia in adults who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy. Immune thrombocytopenia, often called idiopathic thrombocytopenic purpura (ITP), is an immune disorder characterised by low platelet counts.

Augplat 500 mcg Injection contains 'Romiplostim,' which is a thrombopoietin receptor agonist that functions similarly to thrombopoietin. Augplat 500 mcg Injection promotes platelet formation by activating the thrombopoietin receptor. Thereby, Augplat 500 mcg Injection helps treat immune thrombocytopenia effectively.

Augplat 500 mcg Injection will be administered by the healthcare professional. In some cases, Augplat 500 mcg Injection may cause common side effects like headache, joint pain, dizziness, trouble sleeping, muscle tenderness or weakness, pain in the arms and legs and indigestion. These side effects may vary individually. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Notify your doctor if you have allergic reactions to Augplat 500 mcg Injection or other medications. You must inform your doctor if you have leukaemia (blood or bone marrow cancer), bleeding or clotting disorders, or heart, kidney, or liver problems. Augplat 500 mcg Injection is not recommended during pregnancy unless indicated by the doctor. Augplat 500 mcg Injection may make you dizzy; hence drive or operate machinery only when you are alert. Augplat 500 mcg Injection is not recommended for use during breastfeeding.

Augplat 500 mcg Injection contains 'Romiplostim' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune thrombocytopenia. Augplat 500 mcg Injection promotes platelet formation by activating the thrombopoietin receptor. Thereby, Augplat 500 mcg Injection helps treat immune thrombocytopenia effectively.

• Joint pain (arthralgia)
• Dizziness
• Insomnia (inability to sleep)
• Muscle pain (myalgia)
• Pain in extremities
• Abdominal pain
• Shoulder pain
• Dyspepsia (indigestion)
• Paresthesia (tingling or pricking sensation)
• Headache
• Sore throat

Before beginning Augplat 500 mcg Injection, notify your doctor if you have had any allergic reactions to Augplat 500 mcg Injection or any other medications. You must notify your doctor if you have blood or bone marrow cancer (leukaemia), bleeding or clotting disorders, heart, kidney, or liver problems. Augplat 500 mcg Injection is not recommended during pregnancy unless indicated by the doctor. Augplat 500 mcg Injection may make you dizzy hence do not attempt to drive or operate machinery until you are physically stable and mentally alert. Augplat 500 mcg Injection should never be used to normalize platelet counts; Augplat 500 mcg Injection should only be used in ITP patients whose thrombocytopenia and clinical condition increase the risk of bleeding. Augplat 500 mcg Injection is not recommended for use during breastfeeding.

Drug-Drug Interactions: Augplat 500 mcg Injection may interact with anti-cancer medication (e.g. carfilzomib, ibritumomab) and medication used to treat myasthenia gravis (e.g. efgartigimod alfa).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Augplat 500 mcg Injection may interact with disease conditions like leukaemia, liver or kidney impairment.

• EFGARTIGIMOD ALFA
• CARFILZOMIB
• IBRITUMOMAB

• Eating papaya is the greatest natural therapy for increasing platelet count; you can also use a blend of papaya leaves.
• A high protein diet, which includes lean meat, chicken, crab, turkey, beef, and fish, can help improve platelet count.
• Include iron-rich foods such as pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas.
• Platelet counts can be increased by eating foods high in vitamin C, such as guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit, and broccoli.
• Exercise on a regular basis to keep your body and mind healthy.
• Smoking and consuming alcohol should be avoided.
• To reduce the risk of bleeding, avoid activities such as contact sports and the use of sharp objects such as nail cutters and razors.

Immune thrombocytopenia: It is an immune disorder characterised by low platelet counts and abnormal blood clotting. It happens when the immune system destroys its own platelets by mistake. Immune thrombocytopenia symptoms include easy bruising, bleeding from the gums and nose, blood in the urine and stools, heavy menstruation, and pinpoint-sized reddish-purple patches on the lower thighs.