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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Atropine Injectio is used to treat bradycardia (decreased heart rate). It contains Atropine, which restores normal heartbeat during cardiac arrest. It is also used to reduce saliva, mucus, or other secretions in the respiratory tract during surgery. It is further used as an antidote to treat organophosphate insecticide, nerve gas or mushroom poisonings.
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Composition :

ATROPINE-0.6MG

Manufacturer/Marketer :

Harson Laboratories

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Atropine Injectio

Atropine Injectio is used to treat bradycardia (decreased heart rate). It restores normal heartbeat during cardiac arrest. It is also used to reduce saliva, mucus, or other secretions in the respiratory tract during surgery. It is further used as an antidote to treat organophosphate insecticide, nerve gas or mushroom poisonings.

Atropine Injectio contains Atropine, which belongs to the class of muscarinic antagonists or parasympatholytics. It works by blocking the activity of acetylcholine (chemical messenger). As a result, this helps to bring back the blood pressure within the normal range and relaxes the heart. Hence, it treats symptomatic bradycardia and prevents sudden falls in blood pressure.

Atropine Injectio may cause some common side effects like constipation, bloating, stomach pain, nausea, vomiting, dry eyes, blurred vision, dry mouth, fast/pounding heartbeat, flushing (sudden warmth, redness, or tingly feeling), confusion, headache, dizziness, drowsiness, and thirst. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.

Inform your doctor if you are allergic to Atropine Injectio or any of its ingredients. Before using Atropine Injectio, inform your doctor if you have any medical history, including asthma, glaucoma (elevated pressure in the eye), heart rhythm disorder, liver/kidney diseases, enlarged prostate, stomach diseases or myasthenia gravis (muscle weakness). Atropine Injectio may cause blurred vision, dizziness and drowsiness; hence, do not drive or operate machinery until you feel better. Pregnant and breastfeeding women should consult their doctor before using Atropine Injectio. This medicine will be prescribed by a doctor for children depending on the child's age and body weight.

Uses of Atropine Injectio

Treatment of Bradycardia (slow heart rate), an organophosphate insecticide, nerve gas, and mushroom poisoning reduces saliva and mucus secretions in the airway during surgery.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Atropine Injectio contains Atropine, which is an anticholinergic agent, antisialagogue (that inhibits the flow of saliva), and an antidote. It is used to treat bradycardia (slow heart rate). It also restores a normal heartbeat in cardiac arrest or failure patients. It is used as a preoperative medication before anaesthesia to inhibit salivation and excessive secretions of the respiratory tract. It also acts as an antidote to insecticide, nerve gas, and mushroom poisoning. In combination with other medicines, Atropine Injectio is used to reverse the muscle relaxant effect during surgery.

How Atropine Injectio Works

Atropine Injectio contains Atropine, which belongs to the class of muscarinic antagonists or parasympatholytics. It works by blocking the activity of acetylcholine (chemical messenger). As a result, this helps to bring back the blood pressure within the normal range and relaxes the heart. Hence, it treats symptomatic bradycardia and prevents sudden falls in blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Atropine Injectio

  • Constipation
  • Bloating
  • Stomach pain
  • Nausea
  • Vomiting
  • Dry eyes
  • Blurred vision
  • Dry mouth
  • Fast/pounding heartbeat,
  • Flushing (sudden warmth, redness, or tingly feeling)
  • Confusion
  • Headache
  • Dizziness
  • Drowsiness
  • Thirst

What if I have taken an overdose of Atropine Injectio

The overdose of Atropine Injectio is unlikely as it is administered by a doctor. However, in case of overdose, patients may experience very fast heart beat, quick breathing, fever, restlessness, confusion, hallucinations or loss of co-ordination. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Before using Atropine Injectio, inform your doctor if you have any medical history, including asthma, glaucoma, heart rhythm disorder, liver/kidney diseases, enlarged prostate, stomach diseases or myasthenia gravis (muscle weakness). Atropine Injectio may cause blurred vision, dizziness and drowsiness, hence do not drive or operate machinery until you feel better. Pregnant and breastfeeding women should consult their doctor before using Atropine Injectio. Alcohol consumption may worsen the side effect of Atropine Injectio like dizziness and drowsiness. It is better to avoid alcohol while you are being treated with Atropine Injectio. This medicine will be prescribed by a doctor for children depending on the child's age and body weight.

Drug-Drug Interactions

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AtropineSecretin
Severe
AtropineTopiramate
Severe

Drug-Drug Interactions

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AtropineSecretin
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
When Secretin human is used with Atropine Injection10 ml, the therapeutic efficacy of Secretin human can be decrease.

How to manage the interaction:
Although there is a possible interaction between Atropine Injection10 ml and Secretin, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AtropineTopiramate
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
When Atropine Injection10 ml and Topiramate are taken together it can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking Atropine Injection10 ml and topiramate together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
AtropinePotassium citrate
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Taking potassium citrate oral tablets or capsules with Atropine Injection10 ml may increase the irritating effects of potassium on stomach and upper intestine.

How to manage the interaction:
Taking Atropine Injection10 ml with potassium citrate together can result in an interaction, it can be taken if a doctor has advised it. However, if you happen to experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, consult the doctor. Do not discontinue any medications without consulting a doctor.
AtropinePotassium chloride
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Co-administration of Atropine Injection10 ml with Potassium chloride oral tablets or capsules can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
There may be a possibility of interaction between Atropine Injection10 ml and Potassium chloride, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact the doctor right away: severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting(especially with blood), decreased hunger, dark, tarry stools. Do not discontinue any medications without a doctor's advice.
AtropineHydromorphone
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Using Hydromorphone together with Atropine Injection10 ml may increase the risk and/or severity of some side effects (dizziness, drowsiness, confusion, difficulty concentrating, difficulty urinating, dry mouth, abdominal cramping, and constipation).

How to manage the interaction:
Although taking Hydromorphone and Atropine Injection10 ml together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away: trouble peeing, feeling dizzy or sleepy, feeling confused or having trouble focusing, dry mouth, constipation, or feeling less mentally sharp. Do not discontinue any medications without consulting a doctor.
AtropineUmeclidinium bromide
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Using Atropine Injection10 ml together with umeclidinium may increase side effects (drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heartbeat, confusion, memory problems, and glaucoma - an eye disease that causes vision loss in one or both eyes).

How to manage the interaction:
Although taking Atropine Injection10 ml and Umeclidinium bromide together can cause an interaction, it can be taken if a doctor has suggested it. If you experience drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heartbeat, confusion, memory problems, and glaucoma - an eye disease that causes vision loss in one or both eyes. Do not stop using any medications without talking to a doctor.
AtropineZonisamide
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Coadministration of Atropine Injection10 ml and Zonisamide can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking Atropine Injection10 ml and Zonisamide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
AtropinePramlintide
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
Coadministration of Pramlintide with Atropine Injection10 ml can increase the risk of reduced movement in the digestive system.

How to manage the interaction:
Taking Atropine Injection10 ml with Pramlintide together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
AtropineSolifenacin
Severe
How does the drug interact with Atropine Injection10 ml Injection10 ml:
When Atropine Injection10 ml is used with solifenacin may cause side effects (drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems).

How to manage the interaction:
Co- administration of Atropine Injection10 ml with solifenacin can lead to an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, blurred vision, dry mouth, heat intolerance, flushing, reduced sweating, trouble urinating, abdominal cramps, constipation, irregular heartbeat, disorientation, and memory issues, consult the doctor. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your cholesterol and triglyceride levels under control.

  • Eat at regular intervals and maintain a healthy diet that includes fresh fruits and vegetables

  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases

  • Keep a check on your weight and exercise regularly to keep your heart healthy.

  • Your doctor also guides you on noticing and managing the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

ANTICHOLINERGICS

Atropine Injectio Substitute

Substitutes safety advice
  • Atropine Sulphate-1Ml Inj

    by AYUR

    4.51per tablet
  • Atropine Sulphate Injection 1 ml

    by AYUR

    3.60per tablet
  • ATROWOK INJECTION 1ML

    3.51per tablet
  • Atrotas Injection 1ml

    by AYUR

    4.05per tablet
  • Atropine Sulphate Injection 1 ml

    3.60per tablet
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Alcohol

Caution

Alcohol consumption may worsen the side effect of this medicine like dizziness and drowsiness. It is better to avoid alcohol while you are being treated with Atropine Injectio.

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Pregnancy

Caution

Please inform your doctor if you are pregnant or planning pregnancy. Your doctor will prescribe Atropine Injectio only if the benefits outweigh the risk.

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Breast Feeding

Caution

Please inform your doctor if you are breastfeeding. Your doctor will prescribe Atropine Injectio only if the benefits outweigh the risk.

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Driving

Caution

Atropine Injectio may cause side effects like dizziness and drowsiness that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.

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Liver

Caution

Inform your doctor if you have any history of liver diseases or hepatic impairment before receiving Atropine Injectio.

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Kidney

Caution

Inform your doctor if you have any history of kidney diseases/impairment before receiving Atropine Injectio.

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Children

Caution

Please consult your doctor. Your doctor will decide the dose depending on the age and condition of your child.

FAQs

Atropine Injectio belongs to a class of drugs known as 'anticholinergics', used to treat bradycardia (decreased heart rate). It restores normal heartbeat during cardiac arrest. It is also used to reduce saliva, mucus, or other secretions in the respiratory tract during surgery. It is further used as an antidote to treat organophosphate insecticide, nerve gas or mushroom poisonings.
Atropine Injectio contains Atropine, which is used to treat bradycardia (slow heart rate). It works by blocking the activity of acetylcholine (chemical messenger). As a result, this helps to bring back the blood pressure within the normal range and relaxes the heart.
Dry mouth could be a side-effect of Atropine Injectio. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.
Atropine may decrease sweating and make you more prone to heat stroke. Hence, it is advised to avoid becoming overheated or dehydrated during any physical activity and in hot weather.
Atropine is contraindicated in allergic reactions, urinary difficulties, elevated pressure in the eye (glaucoma), and stomach-related disorders like achalasia of the oesophagus, a blockage in the intestine (paralytic ileus) or acute form of colonic distension (toxic megacolon).

Country of origin

INDIA

Manufacturer/Marketer address

12, R. C. Patel Industrial Estate, Akota, Baroda - 390 020., INDIA
Other Info - ATR0063

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