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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Atranza Capsule belongs to a class of drugs called retinoids which is used in the treatment of acne. This medicine works by inhibiting the acne-causing microbes and unblocks pores. Common side effects include dryness of skin, redness, skin irritation, pain or skin flaking.

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Composition :

TRETINOIN-10MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Atranza Capsule

Atranza Capsule belongs to a class of drugs called retinoids (similar to vitamin A). Atranza Capsule is used to treat acute promyelocytic leukaemia (a type of blood problem). Acute promyelocytic leukaemia is a blood cancer that causes a marked increase in a type of immature white blood cells known as promyelocytes in the blood and bone marrow. 

Atranza Capsule contains Tretinoin, a form of vitamin A that works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

Take Atranza Capsule as prescribed. Your doctor will advise you how often you need to take Atranza Capsule based on your medical condition. Some people may experience dizziness, headache, feeling tired, stomach pain, irregular heartbeat, hair loss, bone or joint pain, dry skin and changes in eyesight or hearing. Most of these side effects of Atranza Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Tretinoin, peanuts, soya or any other ingredients in Atranza Capsule, please tell your doctor. Avoid taking Atranza Capsule if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Atranza Capsule as it is excreted into breast milk and may harm the baby. Avoid taking Atranza Capsule if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Atranza Capsule as it may contain sorbitol.

Uses of Atranza Capsule

Treatment of Acute promyelocytic leukaemia

Directions for Use

Take Atranza Capsule preferably with a meal or as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Atranza Capsule is a form of vitamin A that is primarily used to treat acute promyelocytic leukaemia (a type of blood problem). Atranza Capsule reduces the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.  

How Atranza Capsule Works

Atranza Capsule contains Tretinoin, a form of vitamin A that works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Atranza Capsule

  • Dizziness
  • Headache
  • Feeling tired
  • Stomach pain
  • Irregular heartbeat
  • Hair loss
  • Bone or joint pain
  • Dry skin
  • Changes in eyesight or hearing

What if I have taken an overdose of Atranza Capsule

Never take more than the prescribed dose. Atranza Capsule overdose symptoms can include redness, headache, flushing, stomach pain, dizziness, and loss of coordination in addition to cracked and sore lips. Seek immediate medical help if an overdose is suspected.

Drug Warnings

If you are allergic to Tretinoin, peanuts, soya or any other ingredients, please tell your doctor. Avoid taking Atranza Capsule if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Atranza Capsule as it is excreted into breast milk and may harm the baby. You are advised to use effective contraceptive methods while using Atranza Capsule to prevent pregnancy. Avoid taking Atranza Capsule if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Atranza Capsule as it may contain sorbitol.

Drug-Drug Interactions

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TretinoinMinocycline
Critical
TretinoinTetracycline
Critical

Drug-Drug Interactions

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TretinoinMinocycline
Critical
How does the drug interact with Atranza Capsule:
Co-administration of Atranza Capsule with Minocycline can increase the risk of side effects like pseudotumor cerebri (increased pressure in the brain)

How to manage the interaction:
Taking Atranza Capsule with Minocycline is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinTetracycline
Critical
How does the drug interact with Atranza Capsule:
Coadministration of Atranza Capsule with Tetracycline can increase the risk of pseudotumor cerebri(caused by increased pressure in the brain).

How to manage the interaction:
Taking Atranza Capsule with Tetracycline is not recommended, but can be taken together if prescribed by a doctor. However, if you experience headache, nausea, vomiting, and visual disturbances contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinDemeclocycline
Critical
How does the drug interact with Atranza Capsule:
Combining Atranza Capsule with Demeclocycline can increase the risk of side effects like pseudotumor cerebri (increased pressure in the brain)

How to manage the interaction:
Taking Atranza Capsule with Demeclocycline is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headache, nausea, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinDoxycycline
Critical
How does the drug interact with Atranza Capsule:
Coadministration of Atranza Capsule with Doxycycline can increase the risk of side effects like vision problems.

How to manage the interaction:
Taking Atranza Capsule with Doxycycline is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headache, nausea, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinOxytetracycline
Critical
How does the drug interact with Atranza Capsule:
Co-administration of Atranza Capsule with Oxytetracycline can increase the risk of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Oxytetracycline with Atranza Capsule is not recommended as it can be taken if prescribed by a doctor. However, if you experience headaches, nausea, vomiting, and vision problems contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinAcitretin
Severe
How does the drug interact with Atranza Capsule:
Coadministration of Acitretin with Atranza Capsule may increase the risk or severity of hypervitaminosis A (too much vitamin A in the body), increased pressure in the brain, and injury of the liver, pancreas, or digestive tract.

How to manage the interaction:
Although there is a possible interaction between Acitretin and Atranza Capsule, you can take these medicines together if prescribed by your doctor. However, if you notice early signs and symptoms of hypervitaminosis A such as inflammation or bleeding of the gums or lips, dry, scaly, itchy, or red skin, hair loss, headache, dizziness, and nausea, contact a doctor immediately. Avoid or limit the consumption of additional vitamin A while taking these medications. Do not discontinue any medication without consulting a doctor.
TretinoinIsotretinoin
Severe
How does the drug interact with Atranza Capsule:
Taking Isotretinoin together with Atranza Capsule may increase the risk of hypervitaminosis A (excessive vitamin A-related effects).

How to manage the interaction:
Although taking isotretinoin and Atranza Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as increased pressure in the brain (headache, nausea, vomiting, visual disturbances) or liver damage (fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, yellowing of the skin or eyes). Do not stop using any medications without consulting doctor.
TretinoinAprotinin
Severe
How does the drug interact with Atranza Capsule:
Co-administration of Aprotinin and Atranza Capsule may increase the risk of blood clots.

How to manage the interaction:
Co-administration of Atranza Capsule with Aprotinin can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - chest pain, coughing up blood, sudden loss of vision, pain, redness, or swelling in your arm or leg - contact your doctor right away. Do not stop using any medications without a doctor's advice.
TretinoinBexarotene
Severe
How does the drug interact with Atranza Capsule:
Taking Atranza Capsule with Bexarotene may increase the risk of pancreatitis (inflammation of pancreas).

How to manage the interaction:
Although there is a possible interaction between Atranza Capsule and Bexarotene, you can take these medicines together if prescribed by your doctor. If you're having symptoms like nausea, vomiting, or pain in your upper abdomen, contact your doctor right away. Do not discontinue any medications without consulting a doctor.
TretinoinItraconazole
Severe
How does the drug interact with Atranza Capsule:
The blood levels of Atranza Capsule may rise when itraconazole and Atranza Capsule are taken together, which may lead to pseudotumor cerebri(elevated pressure in the brain).

How to manage the interaction:
Atranza Capsule and itraconazole may interact, but if a doctor prescribes them, you can still use them. If you have a headache, nausea, vomiting, blurred vision, sensitivity to light, or ringing in the ears, contact a doctor. Never stop taking a medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat 5 portions of vegetables and fruits in a day.
  • Reduce the intake of salt and fat.

  • Regular exercise may help to reduce depression and excessive tiredness after treatment.

  • Start with gentle walking and once your white blood cell count comes back to normal, you can go swimming.

  • Avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

RETINOIDS

Atranza Capsule Substitute

Substitutes safety advice
  • Asuperz Softgel Capsule 90's

    136.66per tablet
  • CA Atra 10 Softgel Capsule 100's

    78.30per tablet
  • Ematra Soft Gelatin Capsule 100's

    by AYUR

    77.62per tablet
  • Vesanoid Capsule 100's

    91.55per tablet
  • CA Retrans Softgel Capsule 100's

    96.35per tablet
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Alcohol

Caution

Interaction of alcohol with Atranza Capsule is unknown. Please consult a doctor before consuming alcohol while using Atranza Capsule.

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Pregnancy

Unsafe

Atranza Capsule is Category C pregnancy drug and is considered unsafe for pregnant women as it may harm the unborn baby.

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Breast Feeding

Unsafe

Atranza Capsule is excreted into breast milk and may harm the baby. Therefore, you are recommended to avoid breastfeeding while taking Atranza Capsule.

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Driving

Caution

Atranza Capsule may cause dizziness or severe headache. Therefore, drive only if you alert after taking Atranza Capsule.

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Liver

Caution

Take Atranza Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Atranza Capsule with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Atranza Capsule should be given to children only in doses advised by the doctor.

FAQs

Atranza Capsule belongs to a class of drugs called retinoids (similar to vitamin A). Atranza Capsule is used to treat acute promyelocytic leukaemia (a type of blood problem).
Atranza Capsule works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.
You are recommended to avoid pregnancy while taking Atranza Capsule and for 1 month after stopping treatment with Atranza Capsule as it may cause the birth of the deformed baby. Therefore, you are advised to use effective contraceptive measures while taking Atranza Capsule and for 1 month after stopping treatment with Atranza Capsule to prevent pregnancy. Also, women using Atranza Capsule should take a pregnancy test every month and if you become pregnant while taking Atranza Capsule, inform your doctor immediately.
Atranza Capsule may cause dizziness as a temporary side effect. Therefore, drive only if you are alert after taking Atranza Capsule.
You are not recommended to take low-dose progestogens (mini pill) with Atranza Capsule as their effectiveness may be reduced. However, discuss with your doctor if you have any concerns regarding this so that a different oral contraceptive may be prescribed.
Atranza Capsule may cause painful swelling in the leg in a few patients. If you experience painful swelling in your leg, difficulty breathing or sudden chest pain while taking Atranza Capsule, please inform your doctor immediately as these might be signs of a blood clot.

Manufacturer/Marketer address

50Th K.M. Stone, Nh-1, Murthal, Sonepat
Other Info - AT86036

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