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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 9:31 AM IST

Atgam 250 Injection 5 ml is used to prevent and treat acute rejection in patients receiving a kidney transplant. It may also treat aplastic anaemia in patients unsuitable for bone marrow transplantation. It contains Antithymocyte immunoglobulin, which lowers specific cells within the immune system that are likely to attack the transplanted kidney. It helps to stop the body's immune system from rejecting the new kidney.

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Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Atgam 250 Injection 5 ml

Atgam 250 Injection 5 ml belongs to the group of medicines called immunosuppressants indicated for the prevention and treatment of acute rejection in patients receiving a kidney transplant. It may also be used to treat aplastic anaemia in patients unsuitable for bone marrow transplantation.

Atgam 250 Injection 5 ml contains antithymocyte immunoglobulin, which works by preventing the white blood cells within the immune system that are likely to attack the transplanted kidney. It helps to stop the body's immune system from rejecting the new kidney.

In some cases, Atgam 250 Injection 5 ml may cause side effects such as fever, chills, low white blood cell count, low platelet count, blood clotting problems, and skin rash. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Atgam 250 Injection 5 ml. Consult the doctor Atgam 250 Injection 5 ml if you are pregnant. Avoid breastfeeding during treatment. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Atgam 250 Injection 5 ml

Prevention and treatment of Kidney transplant rejection and aplastic anaemia

Medicinal Benefits

Atgam 250 Injection 5 ml belongs to the group of medicines called immunosuppressants indicated for preventing and treating acute rejection in patients receiving a kidney transplant. It may also be used to treat aplastic anaemia in patients unsuitable for bone marrow transplantation. Atgam 250 Injection 5 ml contains Antithymocyte immunoglobulin, which lowers certain cells within the immune system that are likely to attack the transplanted kidney. It helps to stop the body's immune system from rejecting the new kidney.

Side Effects of Atgam 250 Injection 5 ml

  • Fever
  • Chills
  • Low white blood cell count
  • Low platelet count
  • Blood clotting problems
  • Skin rash

Directions for Use

Atgam 250 Injection 5 ml will be administered by a healthcare professional; do not self-administer. It should only be used by physicians experienced in immunosuppressive therapy to treat kidney transplant patients.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Atgam 250 Injection 5 ml if you are allergic to any of its components. Inform the doctor if you have any active infection. Consult the doctor if you are pregnant or think you may be pregnant. Avoid/discontinue breastfeeding during treatment with Atgam 250 Injection 5 ml. Seek medical attention if you experience symptoms of cytokine release syndrome (fever, chills, headache, chest pain, low blood pressure, shortness of breath, fast breathing, and swelling), infusion-associated reactions (generalised rash, fast heart rate, shortness of breath, and low blood pressure), or serum sickness (rash, joint pain, fever, chills, and pain). Let the doctor know if you are taking any other medicines, including supplements and herbal products.

Therapeutic Class

IMMUNOSUPPRESSANTS

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

How Atgam 250 Injection 5 ml Works

Atgam 250 Injection 5 ml contains antithymocyte immunoglobulin, which works by preventing the white blood cells within the immune system that are likely to attack the transplanted kidney. It helps to stop the body's immune system from rejecting the new kidney.

What if I have taken an overdose of Atgam 250 Injection 5 ml

As Atgam 250 Injection 5 ml is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.
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Alcohol

Consult your doctor

It is not known if alcohol affects Atgam 250 Injection 5 ml. Please consult your doctor.

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Pregnancy

Caution

Consult the doctor if you are pregnant, think you may be pregnant or are planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Atgam 250 Injection 5 ml. Seek medical advice before taking this medicine if you want to breastfeed your child.

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Driving

Caution

Do not drive or operate heavy machinery after the treatment with Atgam 250 Injection 5 ml as it may cause side effects. ask your doctor for more information.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Atgam 250 Injection 5 ml.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Atgam 250 Injection 5 ml.

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Children

Consult your doctor

Information about the use of Atgam 250 Injection 5 ml in children is limited. Consult the doctor if you have any concerns.

Country of origin

INDIA

Manufacturer/Marketer address

The Capital, 1802, 18Th Floor , Plot No. C-70, G Block , Bandra Kurla Complex, Bandra East , Mumbai 400051.
Other Info - ATG0001

Author Details

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FAQs

Atgam 250 Injection 5 ml is used to prevent and treat acute rejection in patients receiving a kidney transplant. It may also treat aplastic anaemia in patients unsuitable for bone marrow transplantation.
Atgam 250 Injection 5 ml helps to stop your body's immune system from rejecting the new kidney.
Due to immunosuppressive effects, infections have been reported during treatment with Atgam 250 Injection 5 ml. Careful patient monitoring and appropriate anti-infective prophylaxis are recommended. Consult the doctor immediately if you notice signs of infections such as fever, chills, pale skin, shortness of breath, tiredness, or mouth sores.
Concomitant use of Atgam 250 Injection 5 ml with live vaccines is not advised, as live vaccines may interfere with Atgam 250 Injection 5 ml treatment. Talk to the doctor if you are undergoing any vaccination.

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