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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:46 PM IST
Asvs Polyvalent Injection is used to prevent bleeding in conditions such as oral, pulmonary, traumatic, postoperative, and other external and internal haemorrhages. It contains hemocoagulase which promotes blood clumping and coagulation, thereby effectively controlling bleeding. Additionally, it helps tighten and retract clots, thereby arresting bleeding and promoting wound healing. In some cases, this medicine may cause side effects like pain, swelling, and redness at the site of injection.
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Composition :

HEMOCOAGULASE-1IU

Manufacturer/Marketer :

Serum Institute Of India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Asvs Polyvalent Injection

Asvs Polyvalent Injection belongs to the group of haemostatic agents used to prevent bleeding in conditions such as oral, pulmonary, traumatic, postoperative, and other external and internal haemorrhages. Bleeding is the loss of blood, either within or outside the body. Excess bleeding is called haemorrhage. 

Asvs Polyvalent Injection contains ''Hemocoagulase,'' which is a hemostatic (meaning blood-stopping) enzyme. It exerts a thrombin and thromboplastin-like effect on the process of blood clotting, promoting blood clumping and coagulation and thereby effectively controlling bleeding. The thrombin acts on serum fibrinogen and converts it into stronger fibrin chains which basically help tighten and retract clots, thereby arresting bleeding and promoting wound healing.

Asvs Polyvalent Injection will be administered by a healthcare professional; do not self-administer. In some cases, Asvs Polyvalent Injection may cause certain common side effects like pain, swelling, and redness at the site of injection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

If you are allergic to any of the constituents of Asvs Polyvalent Injection, please inform the doctor. If you are pregnant or breastfeeding, please consult the doctor as Asvs Polyvalent Injection may not be recommended in these states. Asvs Polyvalent Injection should be used cautiously in the elderly or paediatric population. Asvs Polyvalent Injection should be used with caution in those suffering from chronic viral diseases such as HIV or hepatitis. 

Uses of Asvs Polyvalent Injection

Treatment of Haemorrhage (bleeding).

Medicinal Benefits

Asvs Polyvalent Injection belongs to the group of haemostatic agents used to prevent bleeding in conditions such as oral, pulmonary, traumatic, postoperative, and other external and internal haemorrhages. Asvs Polyvalent Injection contains ''Hemocoagulase'', which is a hemostatic (meaning blood-stopping) enzyme. It exerts a thrombin and thromboplastin-like effect on the process of blood clotting, promoting blood clumping and coagulation and thereby effectively controlling bleeding. The thrombin acts on serum fibrinogen and converts it into stronger fibrin chains which basically help tighten and retract clots, thereby arresting bleeding and promoting wound healing.

Side Effects of Asvs Polyvalent Injection

  • Pain at the injection site
  • Redness
  • Swelling

Directions for Use

It will be administered by a qualified medical expert in a hospital setting. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Please inform your doctor of any known allergies or conditions you may suffer, especially severe hypertension, thrombotic disease, DIC, Von Willebrand disease, haemophilia or cardiac and vascular disorders. If you are pregnant or breastfeeding, please consult the doctor. Please notify your doctor if you have a clot-forming tendency. Do not use Asvs Polyvalent Injection if the solution is coloured.

Therapeutic Class

HEMOSTATIC AGENTS

Diet & Lifestyle Advise

  • Include healthy fruits and vegetables in your diet.
  • Avoid processed foods, excess salt and sugar.
  • Snack on nuts and seeds.
  • Avoid saturated foods.

Habit Forming

No

How Asvs Polyvalent Injection Works

Asvs Polyvalent Injection contains ''Hemocoagulase,'' which is a hemostatic (meaning blood-stopping) enzyme. It exerts a thrombin and thromboplastin-like effect on the process of blood clotting, promoting blood clumping and coagulation and thereby effectively controlling bleeding. The thrombin acts on serum fibrinogen and converts it into stronger fibrin chains which basically help tighten and retract clots, thereby arresting bleeding and promoting wound healing.

What if I have taken an overdose of Asvs Polyvalent Injection

It is unlikely to overdose on parenteral medication as it is administered by a healthcare professional. However, seek medical attention if you experience any unusual symptoms.
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Alcohol

Caution

It is not known whether it is safe to consume alcohol with Asvs Polyvalent Injection. It is recommended to avoid alcohol consumption while on treatment with Asvs Polyvalent Injection.

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Pregnancy

Caution

There is limited information on the effects of Asvs Polyvalent Injection on pregnancy. If you are pregnant, inform your doctor before receiving this medicine.

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Breast Feeding

Caution

There is limited information on the effects of Asvs Polyvalent Injection on a breastfeeding woman. If you are breastfeeding, inform your doctor before receiving this medicine.

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Driving

Caution

It is not known whether Asvs Polyvalent Injection affects your driving ability. Avoid driving if you face any side effects that affect your concentration.

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Liver

Caution

There is limited information on the effects of Asvs Polyvalent Injection on the liver. Inform your doctor if you have liver impairment before taking Asvs Polyvalent Injection.

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Kidney

Caution

There is limited information on the effects of Asvs Polyvalent Injection on the kidney. However, severe renal insufficiency can be a contraindication for Asvs Polyvalent Injection. Inform your doctor if you have kidney impairment before taking Asvs Polyvalent Injection.

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Children

Caution

It is unknown whether Asvs Polyvalent Injection is safe for children below 12. Please consult your doctor.

Country of origin

India
Other Info - ASVS432

Author Details

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Asvs Polyvalent Injection Substitute

Substitutes safety advice
  • Troylase 1IU Injection 1 ml

    95.39per tablet
  • Reptilase 1IU Injection

    75.08per tablet

FAQs

Asvs Polyvalent Injection is used to prevent bleeding in conditions such as oral, pulmonary, traumatic, postoperative, and other external and internal haemorrhages.
Asvs Polyvalent Injection exerts thrombin and thromboplastin-like effect on the process of blood clotting, promoting blood clumping and coagulation. Thereby effectively controlling bleeding.
While anaphylaxis is a possible side effect, it is rare, and since Asvs Polyvalent Injection is administered only in a clinical setting, any untoward reaction or side effect can be promptly countered.
Aspirin may interact with Asvs Polyvalent Injection. It is not advisable to take aspirin immediately after administration of Asvs Polyvalent Injection. Please consult your doctor.
Haemocoagulase is the active component of Asvs Polyvalent Injection which promotes blood clot formation.
Asvs Polyvalent Injection will be administered either as intravenously (IV) or intramuscularly (IM) by a qualified medical expert in a hospital setting. Do not self-administer.
The dosage for Asvs Polyvalent Injection will be decided by the doctor based on severity of the bleeding disease or surgical operation.
The common side effects of Asvs Polyvalent Injection are redness, pain, or swelling at the injection site. If any of these side effects persist or worsen, please consult your doctor.
Yes, Asvs Polyvalent Injection may interact with alkaloids (reserpine), hormones (testosterone) and blood-thinners (aspirin, warfarin, Coumadin). Therefore, it is important to inform your doctor about all the medications you are currently taking, including over-the-counter drugs and supplements to avoid potential interactions.
Store Asvs Polyvalent Injection in a cool and dark place at room temperature. Keep it out of the reach of children.

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