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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Asunra 100mg Tablet is used to treat iron overload due to transfusional hemosiderosis (the accumulation of iron in the body due to frequent blood transfusions) or non-transfusion-dependent thalassemia (patients who do not require lifelong regular transfusions for survival). It works by binding to the extra iron and facilitates its removal from the body through faeces. In some cases, this medicine may cause side effects like diarrhoea, vomiting, nausea, abdominal pain, and skin rashes.
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Whats That

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Composition :

DEFERASIROX-100MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Asunra 100mg Tablet

Asunra 100mg Tablet is used for treating chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients two years older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).

The active ingredient in Asunra 100mg Tablet is deferasirox. It is a trivalent iron selective chelating agent. It binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.

Asunra 100mg Tablet is available in the form of oral formulations. Please take Asunra 100mg Tablet in the dose and duration prescribed by your doctor based on specific medical conditions. In some cases, you may experience common side effects such as diarrhoea, vomiting, nausea, abdominal pain, skin rashes, and increased serum creatinine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue using Asunra 100mg Tablet for as long as your doctor has prescribed it. Do not use Asunra 100mg Tablet without a doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using the Asunra 100mg Tablet if you are pregnant or breastfeeding. Do not use Asunra 100mg Tablet in more than prescribed doses or for a longer duration as it may cause adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Asunra 100mg Tablet to rule out any side effects.

Uses of Asunra 100mg Tablet

Used for treating chronic iron overload that occurs due to blood transfusions (transfusional hemosiderosis) in patients two years of age and older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).

Directions for Use

Swallow Asunra 100mg Tablet whole with water; do not crush, break, or chew it.

Medicinal Benefits

Deferasirox is the active component in Asunra 100mg Tablet. It's a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.

How Asunra 100mg Tablet Works

The active ingredient in Asunra 100mg Tablet is deferasirox. It is a trivalent iron selective chelating agent. It binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Asunra 100mg Tablet

  • Diarrhea

  • Vomiting
  • Nausea
  • Abdominal Pain
  • Skin Rashes
  • Increases in Serum Creatinine

What if I have taken an overdose of Asunra 100mg Tablet

Take Asunra 100mg Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Overdose symptoms may include nausea, abdominal pain, vomiting, diarrhoea, and kidney/liver problems that might be serious. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Asunra 100mg Tablet if you are allergic to Asunra 100mg Tablet or its ingredients. Asunra 100mg Tablet is not usually recommended if you are a pregnant or lactating woman; there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the medicine's benefits outweigh the risks. It is unknown whether Asunra 100mg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer. Avoid consuming alcohol along with Asunra 100mg Tablet as it could lead to unpleasant side effects. Should monitor elderly and paediatric patients closely for toxicity.

Drug-Drug Interactions

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DeferasiroxEtodolac
Severe
DeferasiroxAspirin
Severe

Drug-Drug Interactions

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DeferasiroxEtodolac
Severe
How does the drug interact with Asunra 100mg Tablet 6's:
Taking Etodolac with Asunra 100mg Tablet 6's can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Taking Asunra 100mg Tablet 6's with Etodolac together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop taking any medication without consulting a doctor.
DeferasiroxAspirin
Severe
How does the drug interact with Asunra 100mg Tablet 6's:
Using Asunra 100mg Tablet 6's together with Aspirin may increase your risk of developing gastrointestinal ulcers and bleeding.

How to manage the interaction:
Taking Aspirin with Asunra 100mg Tablet 6's together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of hunger, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, breathing difficulty, muscle pains, tiredness, weakness, confusion, and abnormal heart rhythm, consult the doctor. If you experience diarrhea or vomiting while taking these medications, stay hydrated. Do not stop taking any medications without talking to a doctor.
DeferasiroxPrednisolone
Severe
How does the drug interact with Asunra 100mg Tablet 6's:
Co-administration of Asunra 100mg Tablet 6's with Prednisolone can increase the risk of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Although taking Asunra 100mg Tablet 6's with Prednisolone together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience stomach pain, bloating, dizziness, lightheadedness, loss of appetite, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools, you should consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DeferasiroxCholine salicylate
Severe
How does the drug interact with Asunra 100mg Tablet 6's:
Coadministration of Asunra 100mg Tablet 6's and choline salicylate can increase the risk of developing stomach inflammation.

How to manage the interaction:
Although there is an interaction between choline salicylate and Asunra 100mg Tablet 6's, it can be taken if prescribed by a doctor. However, if you experience stomach pain dark stools, vomiting, muscle cramps, palpitations, or diarrhea contact your doctor immediately. Do not stop using any medications without talking to a doctor.
DeferasiroxIbuprofen
Severe
How does the drug interact with Asunra 100mg Tablet 6's:
The combined use of Asunra 100mg Tablet 6's and Ibuprofen can increase the risk of developing gastrointestinal ulcers and bleeding.

How to manage the interaction:
Taking Asunra 100mg Tablet 6's and Ibuprofen together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, black, tarry stools,swelling, shortness of breath, muscle cramps, tiredness, weakness, confusion, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
DeferasiroxMipomersen
Severe
How does the drug interact with Asunra 100mg Tablet 6's:
Mipomersen may cause liver problems and using it with Asunra 100mg Tablet 6's may increase that risk.

How to manage the interaction:
Although taking Asunra 100mg Tablet 6's and Mipomersen together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, bleeding, abdominal pain, or dark urine. Do not discontinue any medications without first consulting your doctor.
DeferasiroxDanaparoid
Severe
How does the drug interact with Asunra 100mg Tablet 6's:
Combining Danaparoid with Asunra 100mg Tablet 6's can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Danaparoid with Asunra 100mg Tablet 6's can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxCilostazol
Severe
How does the drug interact with Asunra 100mg Tablet 6's:
Co-administration of Asunra 100mg Tablet 6's with cilostazol can increase the risk or severity of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Taking Asunra 100mg Tablet 6's with cilostazol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as stomach pain, bloating, dizziness, lightheadedness, decreased hunger, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools. Do not discontinue any medications without consulting a doctor.
DeferasiroxCortisone
Severe
How does the drug interact with Asunra 100mg Tablet 6's:
Using Asunra 100mg Tablet 6's together with cortisone may increase the risk of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Co-administration of Cortisone with Asunra 100mg Tablet 6's can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts. If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxCiclosporin
Severe
How does the drug interact with Asunra 100mg Tablet 6's:
Coadministration of Asunra 100mg Tablet 6's with ciclosporin may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Asunra 100mg Tablet 6's and ciclosporin, they can be taken together if your doctor has prescribed them. However, contact your doctor immediately if experience nausea, vomiting, loss of hunger, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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DEFERASIROX-100MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEFERASIROX-100MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
The blood levels and effects of caffeine may be enhanced by Asunra 100mg Tablet 6's. Avoid consumption of caffeinated drinks during the treatment with Asunra 100mg Tablet 6's. If you experience any unusual symptoms call a doctor.

Diet & Lifestyle Advise

  • Choose foods high in nutrients, such as fruits, vegetables, and whole grains.

  • Replace fatty protein sources with lean alternatives and consume modest quantities of healthy fat sources for improved well-being.

  • Create a diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.

  • Instead of saturated and trans fats, choose monounsaturated and polyunsaturated fats (fish, nuts, and vegetable oils).

  • Select/prepare foods and beverages with fewer added sugars/caloric sweeteners.

  • Be mindful of salt; consume no more than 2,300 mg each day.

  • Limit or avoid alcohol and caffeine consumption.

Habit Forming

No

Therapeutic Class

CHELATING AGENTS

Asunra 100mg Tablet Substitute

Substitutes safety advice
  • Desifer 100 mg Tablet 6's

    by Others

    30.00per tablet
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Alcohol

Caution

Consume alcohol along with Asunra 100mg Tablet is not advisable as it may cause unpleasant side effects, or you also may become more sensitive to the effects of alcohol.

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Pregnancy

Caution

Asunra 100mg Tablet is not usually recommended if you are pregnant. This is because there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks. Please consult the doctor.

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Breast Feeding

Caution

Asunra 100mg Tablet is not usually recommended if you are a lactating woman. This is because there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks.

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Driving

Caution

It is not known whether Asunra 100mg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react.

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Liver

Caution

Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Should be used under the supervision of healthcare provider

FAQs

Asunra 100mg Tablet is used to treat chronic iron overload due to blood transfusions (transfusional hemosiderosis).
Deferasirox is the active component in Asunra 100mg Tablet. It's a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose. Do not take a double dose to make up for the dose that you missed.
Asunra 100mg Tablet is safe if used in the dose and duration recommended by your doctor. Take it precisely as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
The extra iron due to iron overload is stored in pancreas. This damages the pancreas and it does not produce insulin properly. Insulin is required by the body to utilise sugar/glucose efficiently. As insulin is not produced properly, it affects blood sugar levels.
Yes, iron overload is the same as haemochromatosis. Hemochromatosis, or iron overload, is a condition in which your body stores too much iron.
Yes, Asunra 100mg Tablet can be used in children above 2 years if prescribed by the doctor. Talk to the doctor if you have any concerns regarding this.
Asunra 100mg Tablet may cause side effects like diarrhoea, vomiting, nausea, abdominal pain, skin rashes, and increased serum creatinine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

Switzerland

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - ASU0001

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