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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:35 PM IST
Astin Cv 20 Capsule is used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our bodies. It contains Atorvastatin and Clopidogrel, which lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Also, it prevents a clot in the blood vessels. In some cases, it may cause side effects such as headaches, ankle swelling (oedema), slow heart rate, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Micro Labs Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Astin Cv 20 Capsule

Astin Cv 20 Capsule is a combination drug composed of a blood-thinning agent and cholesterol-lowering agent primarily used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our bodies. A heart attack occurs when your coronary arteries (blood vessels supplying blood and oxygen to the heart) becomes blocked due to the build-up of fats (plaque), including cholesterol. These plaques narrow the arteries, leading to atherosclerosis and coronary artery disease, mainly for most heart attacks.

Astin Cv 20 Capsule is composed of two medicines, namely: Atorvastatin and Clopidogrel. Atorvastatin is a lipid-lowering medication which blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Astin Cv 20 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).

You can take Astin Cv 20 Capsule with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take this medicine based on your medical condition. You may sometimes experience headaches, ankle swelling (oedema), slow heart rate, and nausea. Astin Cv 20 Capsule is known to cause dizziness, so driving should be avoided. Most of these side effects of Astin Cv 20 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a Astin Cv 20 Capsule of your own. Suddenly stopping using Astin Cv 20 Capsule may worsen your condition and increase your risk of a future heart attack. Let your doctor know if you are sensitive to atorvastatin or clopidogrel or have any active liver disease (liver enzyme abnormalities), active bleeding issues (like peptic ulcer, brain haemorrhage), or muscle problem (myopathy, rhabdomyolysis). The patient should inform the doctor they are taking Astin Cv 20 Capsule before any surgery or any new medicine is taken. Atorvastatin, present in Astin Cv 20 Capsule is a pregnancy category X drug, so it should not be given to pregnant women. It may cause harm to the foetus if administered to pregnant or breastfeeding women.

Uses of Astin Cv 20 Capsule

Treatment of Hyperlipidemia (Increased cholesterol), Prevention of heart attack, Prevention of stroke.

Medicinal Benefits

Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents clot formation in the blood vessels. Together Astin Cv 20 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Astin Cv 20 Capsule

  • Bleeding (stomach, gastrointestinal, nose bleeding)

  • Rash

  • Diarrhoea

  • Stomach ulcer

  • Muscle disease (like myopathy, rhabdomyolysis)

  • Abdominal pain

Drug Warnings

Tell your doctor if you are sensitive to Atorvastatin or clopidogrel, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), are pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Astin Cv 20 Capsule before any surgery is scheduled or any new medicine is taken. Atorvastatin present in Astin Cv 20 Capsule is a pregnancy category X drug, so it is contraindicated in pregnant women. As it may cause harm to the foetus if administered to pregnant women. The risk of muscle disease might increase if Astin Cv 20 Capsule is taken with an antibiotic (clarithromycin), anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole). Coadministration with anticoagulants like warfarin may cause gastric bleeding and other bleeding problems. So, if you are using any blood-thinning agents, let your doctor know about this. Astin Cv 20 Capsule contains Atorvastatin which can cause muscle problems like myopathy and rhabdomyolysis. Patients with active liver disease should use the Astin Cv 20 Capsule with caution. The safety and effectiveness of Astin Cv 20 Capsule have not been established, so its use should be avoided in paediatric patients or children younger than ten years of age. Discontinuation of Astin Cv 20 Capsule may lead to cardiovascular events like heart attack, stroke and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Astin Cv 20 Capsule .

Drug Interactions

Drug-Drug Interactions: Astin Cv 20 Capsule interacts with antibiotics (e.g. clarithromycin), anti-HIV drugs (e.g. ritonavir, lopinavir, darunavir, atazanavir, indinavir), antifungal (e.g. itraconazole), blood thinners (e.g. warfarin, coumadin, heparin), anti-arthritis drug (e.g. colchicine), heart-related medicine (e.g. digoxin) and immune system affecting drug (e.g. cyclosporine).

Drug-Food Interactions: Alcoholic beverages and grapefruit or its juice intake should be avoided with Astin Cv 20 Capsule . It may interact with Astin Cv 20 Capsule to produce unpleasant side effects like muscle problems and bleeding disorder.

Drug-Disease Interactions: Caution should be exercised while using Astin Cv 20 Capsule in patients with active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), muscle problems or musculoskeletal problems (myopathy, rhabdomyolysis), asthma, and purpura (blood leakage under the skin).

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • RITONAVIR
  • LOPINAVIR
  • DARUNAVIR
  • ATAZANAVIR
  • INDINAVIR
  • ITRACONAZOLE
  • WARFARIN
  • COUMADIN
  • HEPARIN
  • COLCHICINE
  • DIGOXIN
  • CYCLOSPORINE

Habit Forming

No

Diet & Lifestyle Advise

  • Low cholesterol diet along with a regular exercise regime is found to complement treatment with Astin Cv 20 Capsule effectively.

  • Stick to a freshly prepared home-cooked meal and avoid processed, packed foods that contain hidden sugar and extra calories.

  • Try to replace most of your saturated fats with unsaturated fats to reduce total cholesterol and LDL cholesterol (bad cholesterol) quickly.

  • Foods like avocados, olive oil, fatty fish and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.

  • Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.

  • Quit smoking and avoid excessive intake of alcohol.

Special Advise

  • If you have a high cholesterol level, try to have a lipid profile test (LFT) every 6 months.

 

Disease/Condition Glossary

Atherosclerosis: Atherosclerosis occurs when fats, cholesterol, and other substances known as plaque deposit on your artery walls that restrict blood flow. This plaque formation triggers blood clots, narrows the arteries' size, and hardens them. This, in turn, can lead to various heart complications like atherosclerosis, heart attack, heart-related chest pain (angina), and stroke. However, it can also affect the body's arteries apart from the heart.

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Alcohol

Unsafe

Astin Cv 20 Capsule should not be taken with alcohol as it may worsen your liver condition with increased secretion of liver enzymes like transaminase. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

Astin Cv 20 Capsule contains Atorvastatin which is a pregnancy category X medicine. It may cause harm to both the pregnant mother and the fetus. Hence, it is not recommended for pregnant women and those who are planning for a pregnancy. Your doctor might prescribe you only in an extreme case.

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Breast Feeding

Caution

Take Astin Cv 20 Capsule only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Caution

Drive with caution, Astin Cv 20 Capsule usually causes blurry vision and may affect driving ability.

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Liver

Caution

Astin Cv 20 Capsule to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Astin Cv 20 Capsule to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Astin Cv 20 Capsule is not recommended for children below the age of 10 years. The safety and effectiveness of Astin Cv 20 Capsule have not been established in children due to limited testing of Astin Cv 20 Capsule on children by competent authorities worldwide.

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - AST0238

Author Details

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FAQs

Astin Cv 20 Capsule is used to treat Hyperlipidemia (Increased cholesterol), heart attack prevention, and stroke prevention.
Yes, Astin Cv 20 Capsule contains clopidogrel which prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots which in turn prevents the risk of heart attack and stroke.
Yes, taking Astin Cv 20 Capsule can increase the risk of bleeding as it contains aspirin and clopidogrel which belongs to a class of blood-thinning agents. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid any bleeding. Let your doctor know before going any surgical procedure, that you are taking Astin Cv 20 Capsule .
No. Astin Cv 20 Capsule contains Atorvastatin which is pregnancy category X medicine and can cause harm to both pregnant mother and unborn baby. Even if you are planning for pregnancy tell your doctor that you are using Astin Cv 20 Capsule .
Yes, prolonged use of Astin Cv 20 Capsule may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Astin Cv 20 Capsule consult your doctor about this issue.
Do not drink grapefruit juice while taking Astin Cv 20 Capsule . Grapefruit juice may increase the blood-thinning effect of your medicine.
Drinking alcohol with Astin Cv 20 Capsule may damage your liver and increase liver enzymes like transaminase. So, Astin Cv 20 Capsule should be used with caution who consume alcohol and/or have past history of liver disease.
If you accidentally take an overdose of Astin Cv 20 Capsule you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist you should immediately go to the nearby clinic or hospital.
You should have a total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.
Astin Cv 20 Capsule may cause acidity in some cases. Stick to simple meals and avoid spicy food. Do not lie down immediately after eating as it might cause acidity.
Include fruits, vegetables, and whole grains in your diet. Avoid smoking and drinking and try to work out every day as well.
Do not discontinue Astin Cv 20 Capsule without consulting your doctor. Stopping using Astin Cv 20 Capsule may worsen your condition and increase your risk of a future heart attack. To treat your condition effectively, keep taking Astin Cv 20 Capsule for the prescribed duration.
Yes, Astin Cv 20 Capsule is good for cholesterol. It lowers bad cholesterol and increases the levels of good cholesterol.
As Astin Cv 20 Capsule may increase the risk of bleeding, the doctor may ask you to stop taking Astin Cv 20 Capsule before surgery or dental procedure. Inform the doctor that you are taking Astin Cv 20 Capsule if you are due to undergo any surgery.
A low cholesterol diet along with a regular exercise regime is found to complement treatment with Astin Cv 20 Capsule effectively. Avoid fast foods, fried and processed foods.
Paracetamol may be safe while taking Astin Cv 20 Capsule as other painkillers may increase the risk of bleeding. However, consult the doctor before taking any painkillers with Astin Cv 20 Capsule .
Consult the doctor before taking other medicines like antibiotics, anti-HIV drugs, antifungal medicines, blood thinners, anti-arthritis drugs, heart-related medicines and immune system-affecting drugs with Astin Cv 20 Capsule .
Store Astin Cv 20 Capsule at room temperature, in a dry place. Keep out of sight and reach of children.
Side effects of Astin Cv 20 Capsule include headaches, ankle swelling (oedema), slow heart rate, and nausea. If the side effects are persistent, reach out to your doctor.

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