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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Arvast-CF 5 Capsule is used to lower an increased level of total cholesterol (TC) and triglyceride (TG) level. This prevents the risk of having any cardiovascular events like heart attack, stroke, and heart-related chest pain (angina) in the future. It contains Rosuvastatin and Fenofibrate, which lowers the levels of raised lipids known as cholesterol and triglycerides in the blood and increases the good cholesterol (HDL) by blocking body's production of bad cholesterol. It also improves your body's ability to remove it from your blood. In some cases, you may experience side effects such as nausea, headache, abdominal pain, muscle pain, weakness, and daytime drowsiness.

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Prescription drug

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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Arvast-CF 5 Capsule is used to lower an increased level of total cholesterol (TC) and triglyceride (TG) level. This prevents the risk of having any cardiovascular events like heart attack, stroke, and heart-related chest pain (angina) in the future. The blockage of the heart occurs due to the increased level of bad cholesterol (low-density lipoprotein -LDL and triglycerides - TG), which build-up of fat, cholesterol, and other waxy substances layers forming a plaque in the lining of the artery wall (coronary arteries). This increases the chance of having a blood clot and heart attack in an individual.

Arvast-CF 5 Capsule contains Rosuvastatin (statin) and Fenofibrate (fibric acid derivative). Rosuvastatin lowers the levels of raised lipids known as cholesterol and triglycerides in the blood and increases the ‘good’ cholesterol (HDL) by blocking our body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood. On the other hand, Fenofibrate works by lowering the level of triglyceride in the blood. 

You can take Arvast-CF 5 Capsule with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience nausea, headache, abdominal pain, muscle pain, weakness, and daytime drowsiness. Most of these side effects of Arvast-CF 5 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.    

It is important to have your cholesterol and triglyceride levels (lipid profile) checked regularly. This medicine is only one part of a treatment program which should also include a healthy low-fat diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods that are high in fat. Also, please inform your doctor before starting Arvast-CF 5 Capsule if you have kidney problems, are pregnant or breastfeeding, or are diabetic (as you need to monitor your sugar level regularly).

Treatment of Hypertriglyceridemia, Hypercholesterolemia, and Mixed dyslipidaemia.
Swallow Arvast-CF 5 Capsule as a whole with water; do not crush, break or chew it. It is better to take it at a fixed time.

Arvast-CF 5 Capsule is beneficial for patients with Hypertriglyceridemia (high level of triglycerides), Hypercholesterolemia (high level of cholesterol), and Mixed Dyslipidaemia (elevated level of triglycerides – TG, low-density lipoprotein – LDL, and low level of high-density lipoprotein – HDL). Rosuvastatin first increases the LDL (bad cholesterol) in the liver cells for uptake and breakdown. Then, it stops the synthesis of very low-density lipoprotein (VLDL) made by the liver to reduce the total number of bad cholesterols (LDL and VLDL). Fenofibrate works by increasing the enzyme (a natural substance) that breaks down fats or lipids present in the blood. Besides this, Fenofibrate also reduces the raised uric acid levels by increasing the excretion of uric acid through urination. It is also prescribed to diabetes patients with an increased level of lipid and cholesterol to minimize cardiovascular risks like heart attack, stroke, and heart-related chest pain (angina).

Arvast-CF 5 Capsule contains Rosuvastatin (statin) and Fenofibrate (fibric acid derivative). Rosuvastatin lowers the levels of raised lipids known as cholesterol and triglycerides in the blood and increases the ‘good’ cholesterol (HDL) by blocking our body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood. On the other hand, Fenofibrate works by lowering the level of triglyceride in the blood.
Store in a cool and dry place away from sunlight

  • Nausea
  • Headache
  • Abdominal pain
  • Muscle pain (myalgia)
  • General weakness
  • Daytime drowsiness
Do not take more than the prescribed dose of Arvast-CF 5 Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Prolonged intake of statins is reported to cause severe musculoskeletal problems like myopathy and rhabdomyolysis. The most common adverse reactions associated with the use of Arvast-CF 5 Capsule are muscle pain, muscle weakness, stomach upset, nausea, headache, and asthenia (general unexplained weakness). Elderly patients are at greater risk of having muscle problems so it should be given with caution and only after consulting the doctor. Rosuvastatin present in Arvast-CF 5 Capsule is a pregnancy category X medicine (high risk to both pregnant mother and fetus). Hence, it should not be used by pregnant or lactating mothers. Arvast-CF 5 Capsule also passes into the breast milk but its safety and efficiency are unclear, so its intake should be avoided by the nursing mother. The use of a Arvast-CF 5 Capsule should be avoided in all kidney patients and to be taken with caution in all liver disease patients. The use of alcohol with Arvast-CF 5 Capsule increases liver damage, so its use should be avoided. Arvast-CF 5 Capsule contains fenofibrate which is contraindicated in gallstone patients, as there is an increased level of cholesterol in the bile leading to cholelithiasis.

verifiedApollotooltip
RosuvastatinSaquinavir
Severe
RosuvastatinFenofibrate
Severe

Drug-Drug Interactions

RosuvastatinSaquinavir
Severe
How does the drug interact with Arvast-CF 5 Capsule 10's:
Co-administration of Saquinavir and Arvast-CF 5 Capsule 10's can increase the blood levels of Arvast-CF 5 Capsule 10's and can increase the risk of developing liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Saquinavir and Arvast-CF 5 Capsule 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinFenofibrate
Severe
How does the drug interact with Arvast-CF 5 Capsule 10's:
Co-administration of Arvast-CF 5 Capsule 10's and Fenofibrate can increase the blood levels of Arvast-CF 5 Capsule 10's and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Arvast-CF 5 Capsule 10's and Fenofibrate can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinSimeprevir
Severe
How does the drug interact with Arvast-CF 5 Capsule 10's:
Co-administration of Simeprevir and Arvast-CF 5 Capsule 10's can increase the blood levels of Arvast-CF 5 Capsule 10's and can increase the risk of side effects like liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Simeprevir and Arvast-CF 5 Capsule 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinAmprenavir
Severe
How does the drug interact with Arvast-CF 5 Capsule 10's:
Co-administration of Arvast-CF 5 Capsule 10's and amprenavir can increase the blood levels of Arvast-CF 5 Capsule 10's and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Arvast-CF 5 Capsule 10's and Amprenavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinNicotinamide
Severe
How does the drug interact with Arvast-CF 5 Capsule 10's:
Coadministration of Nicotinamide with Arvast-CF 5 Capsule 10's may increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage which can be fatal.

How to manage the interaction:
Taking Nicotinamide with Arvast-CF 5 Capsule 10's together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like unexplained muscle pain, muscle stiffness or tenderness, fever, dark-coloured urine, or weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
RosuvastatinColchicine
Severe
How does the drug interact with Arvast-CF 5 Capsule 10's:
Coadministration of colchicine and Arvast-CF 5 Capsule 10's may increase the risk of conditions that affect your muscles and kidneys.

How to manage the interaction:
Taking Colchicine with Arvast-CF 5 Capsule 10's may possibly result in an interaction, but they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience abdominal discomfort, nausea, vomiting, diarrhea, back pain, weakness, or tingling or numbness in your hands and feet. Do not discontinue any medication without consulting your doctor.
RosuvastatinAtazanavir
Severe
How does the drug interact with Arvast-CF 5 Capsule 10's:
Co-administration of Arvast-CF 5 Capsule 10's and Atazanavir can increase the blood levels of Arvast-CF 5 Capsule 10's and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Arvast-CF 5 Capsule 10's and Atazanavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinLenalidomide
Severe
How does the drug interact with Arvast-CF 5 Capsule 10's:
Co-administration of Arvast-CF 5 Capsule 10's with lenalidomide may increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is an interaction between lenalidomide and Arvast-CF 5 Capsule 10's, it can be taken if prescribed by a doctor. However, if you experience muscle pain, tenderness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
RosuvastatinLeflunomide
Severe
How does the drug interact with Arvast-CF 5 Capsule 10's:
Co-administration of leflunomide and Arvast-CF 5 Capsule 10's can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Arvast-CF 5 Capsule 10's can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RosuvastatinGemfibrozil
Severe
How does the drug interact with Arvast-CF 5 Capsule 10's:
Co-administration of Gemfibrozil and Arvast-CF 5 Capsule 10's may increase the risk or severity of side effects like muscle injury.

How to manage the interaction:
Co-administration of Gemfibrozil and Arvast-CF 5 Capsule 10's can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • A low-fat diet is advised to lower levels of fat in the blood.
  • As a precautionary measure, you are recommended not to consume alcohol, or junk food items from outside, stick to freshly prepared home-cooked meals and take proper rest, for a speedy recovery.
  • And also try to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL cholesterol in a short span of time.
  • Foods like avocados, olive oil, fatty fish and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
  • Regular exercise can make your heart strong and decrease your risk of a heart attack.
No
ANTILIPEMICS
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Unsafe

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Unsafe

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Caution

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Safe if prescribed

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Caution

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Caution

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Caution

FAQs

Arvast-CF 5 Capsule is used to lower increased levels of total cholesterol (TC) and triglyceride (TG) levels. This prevents the risk of having any cardiovascular events like heart attack, stroke, and heart-related chest pain (angina) in the future.
Usually, it is not safe to take Arvast-CF 5 Capsule with fusidic acid as it may lead to muscle weakness, tenderness or pain. Please consult your doctor before taking Arvast-CF 5 Capsule along with fusidic acid.
Yes, taking Arvast-CF 5 Capsule can cause muscle pain (myalgia) and long term complications like rhabdomyolysis and myopathy. Also please tell your doctor if you have a muscle weakness that is constant.
Yes, Arvast-CF 5 Capsule can be taken at night or any other time with or without food. It is better to take it at fixed time.
Yes Arvast-CF 5 Capsule can make you feel tired as it reduces the energy supply to the muscles in the body. People suffering from heart or liver diseases feel more tired while taking Arvast-CF 5 Capsule . Please consult your doctor if you feel tired while taking Arvast-CF 5 Capsule .
No, Arvast-CF 5 Capsule does not cause weight gain. If you experience weight gain while you are taking Arvast-CF 5 Capsule , please consult your doctor.
No, Arvast-CF 5 Capsule should not be stopped even if you feel better as it lead to worsening of your condition. Please consult your doctor if you feel better and do as advised.
Yes. Arvast-CF 5 Capsule is also prescribed for the treatment of diabetic dyslipidemia (high cholesterol and lipid in diabetes). However, you should consult doctor before using Arvast-CF 5 Capsule .
Arvast-CF 5 Capsule contains Rosuvastatin (statin) and Fenofibrate (fibric acid derivative), which help treat high cholesterol.
No, Arvast-CF 5 Capsule is not a blood thinner. It is a cholesterol-lowering medicine.
Arvast-CF 5 Capsule should be swallowed as a whole with water; do not crush or chew it.
Side effects of Arvast-CF 5 Capsule are nausea, headache, abdominal pain, muscle pain, weakness, and daytime drowsiness. If the side effects are persistent, reach out to your doctor.
Liver damage is a very rare side effect of Arvast-CF 5 Capsule . Let the doctor know if you have liver problems.
Follow a low-fat diet, avoid fried foods, exercise regularly, and do not drink alcohol.
Consult the doctor before taking Arvast-CF 5 Capsule with other medicines like immunosuppressants, bile affecting pills, anti-HIV drugs, blood thinners and anti-arthritis pills.
Take Arvast-CF 5 Capsule at a fixed time daily as it will help you to remember taking the medicine.
Arvast-CF 5 Capsule should not be taken by people who are allergic to any of its components and pregnant women.
You are recommended not to consume alcohol along with Arvast-CF 5 Capsule to avoid unpleasant side-effects like drowsiness, dizziness, or sleepiness.
Store Arvast-CF 5 Capsule at room temperature, in a dry place. Keep out of sight and reach of children.
India
Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ARV0021

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