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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Arnx 100 Tablet is used to treat heart failure. It helps reduce the risk of hospitalisation and death in adults with chronic heart failure. It works by relaxing and widening the blood vessels and making it easier for the heart to pump blood to all body parts. In some cases, this medicine may cause side effects such as cough, dizziness, nausea, diarrhoea, and weakness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Arnx 100 Tablet

Arnx 100 Tablet is used in the treatment of heart failure. It helps to reduce the risk of death and hospitalization in adults with chronic heart failure. Also, it can be used in children 1 to less than 18 years old to treat heart failure. Heart failure is a chronic condition in which the heart cannot pump blood as effectively as it should.

Arnx 100 Tablet is a combination of two medicines: Valsartan and sacubitril. Valsartan belongs to the class of drugs called angiotensin receptor blockers (ARBs) that block the effect of angiotensin II receptors that tighten the blood vessels. By blocking the effect of angiotensin II receptors, Valsartan makes it easier for the heart to pump blood to all body parts by relaxing and widening the blood vessels. Sacubitril belongs to the class of drugs known as neprilysin inhibitors, which work by relaxing and widening the blood vessels and making it easier for the heart to pump blood to all body parts. Together, Arnx 100 Tablet helps in the treatment of heart failure.

Take Arnx 100 Tablet with or without food or as directed by your doctor. Do not crush, chew or break the tablet; swallow it as a whole with a glass of water. You are advised to take Arnx 100 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as cough, dizziness, nausea, diarrhoea, and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Arnx 100 Tablet for as long as your doctor has prescribed it. Try not to stop taking it on your own as it may cause a sudden increase the blood pressure, chest pain, or heart attack.  Do not be reluctant to speak with your doctor if you experience any difficulty while taking Arnx 100 Tablet . Do not take Arnx 100 Tablet with ACE inhibitors (such as captopril or enalapril) since the risk of side effects may increase. Do not take Arnx 100 Tablet for at least 36 hours before or after taking an ACE inhibitor drug. Inform your doctor before taking Arnx 100 Tablet if you have kidney or liver problems, if you are pregnant or breastfeeding, or if you have a history of hereditary angioedema (rapid oedema or swelling beneath the area of skin).

Uses of Arnx 100 Tablet

Treatment of Heart failure.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Arnx 100 Tablet is a combination of two medicines, Valsartan and sacubitril. Valsartan belongs to the class of drugs called angiotensin receptor blockers (ARBs) that block the effect of angiotensin II receptors that tighten the blood vessels. By blocking the effect of angiotensin II receptors, Valsartan makes it easier for the heart to pump blood to all body parts by relaxing and widening the blood vessels. Sacubitril belongs to the class of drugs known as neprilysin inhibitors, which work by relaxing and widening the blood vessels and making it easier for the heart to pump blood to all body parts. Arnx 100 Tablet helps in the treatment of certain types of heart failure. It may also help you to live longer and lower the frequency of hospitalizations for heart failure.

How Arnx 100 Tablet Works

Arnx 100 Tablet is a combination of two medicines: Valsartan and sacubitril. Valsartan belongs to the class of drugs called angiotensin receptor blockers (ARBs) that block the effect of angiotensin II receptors that tighten the blood vessels. By blocking the effect of angiotensin II receptors, Valsartan makes it easier for the heart to pump blood to all body parts by relaxing and widening the blood vessels. Sacubitril belongs to the class of drugs known as neprilysin inhibitors, which work by relaxing and widening the blood vessels and making it easier for the heart to pump blood to all body parts. Together, Arnx 100 Tablet helps in the treatment of heart failure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Arnx 100 Tablet

  • Cough

  • Dizziness

  • Diarrhea

  • Fainting

  • Headache

  • Nausea

  • Stomach pain

  • Vertigo (sensation of feeling off-balance)

  • Weakness

What if I have taken an overdose of Arnx 100 Tablet

Take Arnx 100 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dizziness, fainting, and hypotension (low blood pressure). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Keep your doctor informed if you have kidney or liver diseases. Discuss with your doctor if you are taking any other medicines along with Arnx 100 Tablet . Avoid smoking and alcohol consumption. Pregnant women and breastfeeding women should consult their doctor before taking Arnx 100 Tablet . A prolonged intake of Arnx 100 Tablet can cause an altered potassium level so, regular monitoring of potassium is required. Driving and operating heavy machinery should not be done as it may cause dizziness and drowsiness. Orthostatic hypotension (sudden lowering of blood pressure n standing) might occur, so patients using Arnx 100 Tablet should get up with caution. Speak to your doctor if you have diabetes before taking Arnx 100 Tablet . Inform your doctor about your current medicines such as aliskiren (medication to treat high blood pressure), any other heart or blood pressure medicines, lithium, mineral supplements that contain potassium. Inform your doctor if you feel light-headed or have little or no urination, rapid weight gain, swelling in your hands, feet, or ankles after taking Arnx 100 Tablet .

Drug-Drug Interactions

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ValsartanAliskiren
Critical
ValsartanLisinopril
Severe

Drug-Drug Interactions

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ValsartanAliskiren
Critical
How does the drug interact with Arnx 100 Tablet:
Using Aliskiren together with Arnx 100 Tablet may increase the risk of serious side effects (kidney problems, low blood pressure, or high potassium levels).

How to manage the interaction:
Taking Arnx 100 Tablet with Aliskiren is not advised as it can result in an interaction, it can be taken if a doctor has advised it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
ValsartanLisinopril
Severe
How does the drug interact with Arnx 100 Tablet:
Coadministration of Lisinopril and Arnx 100 Tablet may increase the risk of side effects (low blood pressure, kidney function impairment, hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Lisinopril together with Arnx 100 Tablet may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience symptoms, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
ValsartanCaptopril
Severe
How does the drug interact with Arnx 100 Tablet:
The use of Captopril and Arnx 100 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Arnx 100 Tablet and Captopril, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, contact a doctor. Do not discontinue any medications without a doctor's advice.
ValsartanAmiloride
Severe
How does the drug interact with Arnx 100 Tablet:
Taking amiloride with Arnx 100 Tablet may increase potassium levels in the blood. (High levels of potassium can cause hyperkalemia - high level of potassium in the blood, which can lead to kidney failure, muscular paralysis, and abnormal heart rhythms).

How to manage the interaction:
Although taking amiloride and Arnx 100 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
ValsartanPotassium iodide
Severe
How does the drug interact with Arnx 100 Tablet:
Coadministration of Potassium iodide and Arnx 100 Tablet may significantly increase potassium levels in the blood, which in severe cases can lead to kidney failure.

How to manage the interaction:
Although taking Potassium iodide together with Arnx 100 Tablet may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
ValsartanTriamterene
Severe
How does the drug interact with Arnx 100 Tablet:
The use of Triamterene and Arnx 100 Tablet may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Triamterene together with Arnx 100 Tablet may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medication without consulting a doctor.
ValsartanTizanidine
Severe
How does the drug interact with Arnx 100 Tablet:
Coadministration of Tizanidine and Arnx 100 Tablet may increase the risk of low blood pressure.

How to manage the interaction:
Although taking Tizanidine together with Arnx 100 Tablet may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate, contact a doctor. Do not discontinue any medication without consulting a doctor.
ValsartanPotassium citrate
Severe
How does the drug interact with Arnx 100 Tablet:
Co-administration of Potassium citrate with Arnx 100 Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Potassium citrate together with Arnx 100 Tablet may result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
ValsartanEnalapril
Severe
How does the drug interact with Arnx 100 Tablet:
Combine use of Enalapril and Arnx 100 Tablet can increase the effect of Arnx 100 Tablet.

How to manage the interaction:
Although taking Enalapril together with Arnx 100 Tablet may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
ValsartanBenazepril
Severe
How does the drug interact with Arnx 100 Tablet:
Coadministration of Benazepril and Arnx 100 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Arnx 100 Tablet and Benazepril, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, contact a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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SACUBITRIL-49MG+VALSARTAN-51MGPotassium rich foods
Moderate

Drug-Food Interactions

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SACUBITRIL-49MG+VALSARTAN-51MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Co-administration of Arnx 100 Tablet along with moderate-to-high dietary potassium intake, especially salt substitutes may lead to high potassium levels in the blood. Avoid taking potassium-containing salt substitutes or over-the-counter potassium supplements along with Arnx 100 Tablet as this can lead to high potassium levels in blood. However, if you experience weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs, consult a doctor.

Diet & Lifestyle Advise

  • You are advised to consume low salt and low-fat diet while taking Arnx 100 Tablet .

  • Regular exercise is also recommended to complement treatment with Arnx 100 Tablet .

  • Eat a diet rich in whole grains, vegetables, fruits.

  • Avoid smoking and alcohol consumption.

  • Maintain a healthy weight with proper diet and exercise.

  • Managing stress with meditation, yoga, massage would also help in treating high blood pressure.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Arnx 100 Tablet Substitute

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Arnx 100 Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

It is not recommended to take Arnx 100 Tablet while you are pregnant. Please consult your doctor. Your doctor will decide whether Arnx 100 Tablet can be given to pregnant women or not.

bannner image

Breast Feeding

Unsafe

It is not recommended to take Arnx 100 Tablet while you are breast-feeding. Please consult your doctor. Your doctor will decide whether Arnx 100 Tablet can be given to breast-feeding mothers or not.

bannner image

Driving

Caution

Arnx 100 Tablet may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

bannner image

Liver

Caution

Dose adjustment may be needed. Arnx 100 Tablet should be used with caution in patients with liver impairment/liver disease.

bannner image

Kidney

Caution

Dose adjustment may be needed. Arnx 100 Tablet should be used with caution in patients with kidney impairment/kidney disease.

bannner image

Children

Unsafe

Arnx 100 Tablet can be used to treat heart failure in children who are at least 1 year old when prescribed by a child specialist

FAQs

Arnx 100 Tablet is used in the treatment of heart failure. It helps to reduce the risk of death and hospitalization in adults with chronic heart failure. Also, it can be used in children 1 to less than 18 years old to treat heart failure.

Arnx 100 Tablet is a combination of Valsartan and sacubitril. Valsartan belongs to the class of drugs called angiotensin receptor blockers (ARBs) that block the effect of angiotensin II receptors that tighten the blood vessels. By blocking the effect of angiotensin II receptors, Valsartan makes it easier for the heart to pump blood to all body parts by relaxing and widening the blood vessels. Sacubitril belongs to the class of drugs known as neprilysin inhibitors which work by relaxing and widening the blood vessels and makes it easier for the heart to pump blood to all body parts. Arnx 100 Tablet helps in the treatment of certain types of heart failure. It may also help you to live longer and lowers the frequency of hospitalizations for heart failure.

Please do not stop taking Arnx 100 Tablet without consulting your doctor on your own as it may lead to rising in blood pressure. Continue taking Arnx 100 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Arnx 100 Tablet .

Orthostatic hypotension could be a side-effect of Arnx 100 Tablet . Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Arnx 100 Tablet are advised to monitor their blood pressure levels to avoid unpleasant events regularly.

High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the heart, brain, and kidney's blood vessels, resulting in a stroke, heart failure, or kidney failure. Hypertension increases the risk of heart attacks.

Country of origin

India

Manufacturer/Marketer address

D' Block, 3Rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - ARN0079

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