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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Arkadep 20mg Tablet is used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder. It contains Fluoxetine, which increases serotonin concentrations and helps in regulating mood and treats depression. In some cases, you may experience common side effects such as insomnia (difficulty sleeping), headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

FLUOXETINE-20MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Arkadep 20mg Tablet

Arkadep 20mg Tablet belongs to a group of medicines called antidepressants used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder. Depression is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.
 
Arkadep 20mg Tablet contains ‘Fluoxetine’ which is a selective serotonin reuptake inhibitor. It works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.
 
Take Arkadep 20mg Tablet as prescribed. You are advised to take Arkadep 20mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as insomnia (difficulty sleeping), headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and indigestion. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Please do not stop taking Arkadep 20mg Tablet on your own as it could lead to withdrawal symptoms. Do not take Arkadep 20mg Tablet if you are pregnant or breastfeeding unless prescribed. Do not drive or operate machinery as Arkadep 20mg Tablet may cause dizziness and might impair your reactions. Arkadep 20mg Tablet should not be given to children below 8years as the safety and effectiveness have not been established. Avoid consuming alcohol along with Arkadep 20mg Tablet as it could lead to increased dizziness.  Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Arkadep 20mg Tablet

Treatment of Depression, Obsessive-Compulsive Disorder (OCD), Bulimia nervosa (eating disorder).

Directions for Use

Take Arkadep 20mg Tablet with or without food. Your doctor will decide for how long you need to take Arkadep 20mg Tablet based on your medical condition and response to treatment. Take Arkadep 20mg Tablet exactly as prescribed by the doctor. Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Medicinal Benefits

Arkadep 20mg Tablet belongs to a group of antidepressant medicines called selective serotonin reuptake inhibitors. Arkadep 20mg Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder with or without agoraphobia. Arkadep 20mg Tablet works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression. Arkadep 20mg Tablet may also be used to treat premenstrual dysphoric disorder (a severe form of premenstrual syndrome). Arkadep 20mg Tablet has fewer unwanted effects than other antidepressant drugs. Arkadep 20mg Tablet is used in combination with other drugs to treat bipolar disorder and treatment-resistant depression.

How Arkadep 20mg Tablet Works

Arkadep 20mg Tablet contains ‘Fluoxetine’ which is a selective serotonin reuptake inhibitor. It works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Arkadep 20mg Tablet

  • Insomnia (difficulty sleeping)
  • Headache
  • Diarrhoea
  • Nausea
  • Fatigue
  • Dry mouth
  • Loss of appetite
  • Indigestion

What if I have taken an overdose of Arkadep 20mg Tablet

Do not take more than the prescribed dose of Arkadep 20mg Tablet as it may cause overdose. The symptoms of overdose include drowsiness, tremor, fast heart rate, vomiting and nausea. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Arkadep 20mg Tablet if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MOA) or have taken them in the last 14days, or if you are taking metoprolol (used to treat high blood pressure). Do not take Arkadep 20mg Tablet along with opioid antagonists such as buprenorphine and naloxone as it might lead to a serious condition called serotonin syndrome. Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself. Inform your doctor if you have/had epilepsy, mania, glaucoma, diabetes, bleeding disorders, or hyponatremia (low sodium levels).  Do not take Arkadep 20mg Tablet if you are pregnant or breastfeeding unless prescribed. Do not drive or operate machinery as Arkadep 20mg Tablet may cause dizziness and might impair your reactions. Arkadep 20mg Tablet should not be given to children below 8years as the safety and effectiveness have not been established. Avoid consuming alcohol along with Arkadep 20mg Tablet as it could lead to increased dizziness. 

Drug-Drug Interactions

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FluoxetineCisapride
Severe
FluoxetineRasagiline
Severe

Drug-Drug Interactions

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FluoxetineCisapride
Severe
How does the drug interact with Arkadep 20mg Tablet:
Taking Arkadep 20mg Tablet with Cisapride may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Arkadep 20mg Tablet can be taken with Cisapride if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.
FluoxetineRasagiline
Severe
How does the drug interact with Arkadep 20mg Tablet:
Taking rasagiline with Arkadep 20mg Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction, Arkadep 20mg Tablet can be taken with rasagiline if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
FluoxetineMifepristone
Severe
How does the drug interact with Arkadep 20mg Tablet:
Co-administration of Arkadep 20mg Tablet with mifepristone can increase the risk of irregular heart rhythm. Prolonged treatment with Mifepristone may result in low potassium levels.

How to manage the interaction:
Taking Arkadep 20mg Tablet with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
FluoxetineDisopyramide
Severe
How does the drug interact with Arkadep 20mg Tablet:
Taking Arkadep 20mg Tablet with disopyramide may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Arkadep 20mg Tablet can be taken with disopyramide if prescribed by the doctor. Consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications.
FluoxetinePethidine
Severe
How does the drug interact with Arkadep 20mg Tablet:
Co-administration of Meperidine with Arkadep 20mg Tablet can increase the risk of serotonin levels in the body.

How to manage the interaction:
There may be a possibility of interaction between Pethidine and Arkadep 20mg Tablet, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FluoxetineVilazodone
Severe
How does the drug interact with Arkadep 20mg Tablet:
When Vilazodone is taken with Arkadep 20mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Although there is a possible interaction, Arkadep 20mg Tablet can be taken with Vilazodone if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue the medications without consulting a doctor.
FluoxetineAmitriptyline
Severe
How does the drug interact with Arkadep 20mg Tablet:
Co-administration of Amitriptyline with Arkadep 20mg Tablet can result in Serotonin syndrome (a condition wherein serotonin levels are increased in the body).

How to manage the interaction:
Although using Arkadep 20mg Tablet and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. You may also experience symptoms like urinary retention, drowsiness, dry mouth, blurred vision, and constipation. Do not discontinue any medications without consulting a doctor.
FluoxetineTapentadol
Severe
How does the drug interact with Arkadep 20mg Tablet:
Taking Tapentadol together with Arkadep 20mg Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction, Arkadep 20mg Tablet can be taken with tapentadol if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medication without consulting a doctor.
FluoxetinePhenelzine
Severe
How does the drug interact with Arkadep 20mg Tablet:
Taking Arkadep 20mg Tablet with phenelzine may increase the risk of a serotonin levels in the body.

How to manage the interaction:
Although there is a possible interaction, Arkadep 20mg Tablet can be taken with phenelzine if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhoea. Treatment with Arkadep 20mg Tablet should be started 14 days after stopping phenelzine.
FluoxetineGatifloxacin
Severe
How does the drug interact with Arkadep 20mg Tablet:
Taking Arkadep 20mg Tablet with gatifloxacin may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Arkadep 20mg Tablet can be taken with gatifloxacin if prescribed by the doctor. Consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

Arkadep 20mg Tablet Substitute

Substitutes safety advice
  • Fludac Capsule 15's

    by Others

    3.90per tablet
  • Prodep Capsule 10's

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    4.01per tablet
  • Flunil-20 Capsule 10's

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    4.01per tablet
  • Flunil Suspension 60 ml

    by Others

    1.79per tablet
  • Floatin-20 Tablet 10's

    by Others

    4.01per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Arkadep 20mg Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Arkadep 20mg Tablet belongs to pregnancy category C. Please consult your doctor before taking Arkadep 20mg Tablet if you are pregnant, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Arkadep 20mg Tablet may pass into breastmilk. Consult your doctor before taking Arkadep 20mg Tablet; your doctor will decide whether Arkadep 20mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Arkadep 20mg Tablet may cause dizziness and might impair your reactions. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Arkadep 20mg Tablet should not be given to children below 8years as the safety and effectiveness have not been established.

FAQs

Arkadep 20mg Tablet is used to treat Depression, Obsessive-Compulsive Disorder (OCD), and Bulimia nervosa (eating disorder).

Arkadep 20mg Tablet works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.

Do not discontinue Arkadep 20mg Tablet without consulting your doctor as it could lead to withdrawal effects. To treat your condition effectually continue taking Arkadep 20mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Arkadep 20mg Tablet; the doctor may reduce the dose gradually.

Arkadep 20mg Tablet may cause decreased sex-drive, problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.

Dry mouth could be a side-effect of Arkadep 20mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Please consult your doctor before taking Arkadep 20mg Tablet if you have glaucoma as it might cause increased pressure in the eye.

Consult tour doctor before taking Arkadep 20mg Tablet if you are diabetic as it might fluctuate blood glucose levels. Regular monitoring of blood sugar levels is advised if you are taking Arkadep 20mg Tablet. Talk to your doctor if you experience fluctuations in blood sugar levels.

Arkadep 20mg Tablet might increase the risk of bone fractures. Talk to your doctor before taking Arkadep 20mg Tablet if you have osteoporosis. Consult your doctor if you experience bone pain.

Arkadep 20mg Tablet may cause weight loss due to loss of appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight. Please consult your doctor if you experience fluctuations in weight while taking Arkadep 20mg Tablet.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India.
Other Info - AR16197

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