Apidra 100IU /ml Injection is rapid-acting insulin used for the treatment of diabetes mellitus in both children (above six years of age) and adults. The active ingredient in Apidra 100IU /ml Injection is insulin glulisine. Apidra 100IU /ml Injection is a recombinant human insulin analogue that is equipotent to regular human insulin. Insulin glulisine has a more rapid onset of action and a shorter duration of action than regular human insulin. Diabetes is a lifelong condition that causes a person's blood sugar level to become too high.

Apidra 100IU /ml Injection is a fast-acting insulin that works rapidly to normalise blood sugar levels after a meal. It typically begins working within 10-20 minutes after injection, peaks in about 1 hour, and keeps working for 2 to 4 hours. Due to this short action, Apidra 100IU /ml Injection should normally be taken in combination with intermediate-acting or long-acting insulin preparations. Apidra 100IU /ml Injection works by ensuring rapid and consistent sugar control. Apidra 100IU /ml Injection is a fast-acting form of insulin that helps lower blood sugar levels after food intake. Prevents the risk of having severe complications of diabetes.

The primary role of insulin and insulin analogues, including insulin glulisine, is glucose metabolism control. Insulin lowers blood glucose levels by stimulating peripheral glucose uptake, particularly skeletal muscle and fat, and inhibiting hepatic glucose production. Insulin glulisine takes effect about twice as fast as regular human insulin and completes the glucose-lowering effect about 2 hours earlier than regular human insulin.

Your doctor will advise you on how to use Apidra 100IU /ml Injection. It should be administered at least 0-15 minutes before or soon after meals. The common side effects of Apidra 100IU /ml Injection are hypokalaemia (low potassium), hypoglycaemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and pruritus (itch skin), which may occur at the injection site. Most of these side effects of Apidra 100IU /ml Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Apidra 100IU /ml Injection of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Apidra 100IU /ml Injection if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Apidra 100IU /ml Injection, you should take a healthy diet, exercise regularly, and maintain weight as your doctor advises. Apidra 100IU /ml Injection is a cold chain medicine, so it must be stored in the refrigerator between 2-8 degrees Celsius; otherwise, its efficiency might get lost. Do not store it in the freezer of the fridge.

The primary role of insulin and insulin analogues, including insulin glulisine, is glucose metabolism control. Insulin lowers blood glucose levels by stimulating peripheral glucose uptake, particularly skeletal muscle and fat, and inhibiting hepatic glucose production. Apidra 100IU /ml Injection works by ensuring rapid and consistent sugar control. Apidra 100IU /ml Injection is a fast-acting form of insulin that helps lower blood sugar levels after food intake. Prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses sugar production in the liver. Apidra 100IU /ml Injection helps in improving the glycaemic control, which in turn decreases the risk of progression of complications of diabetes like damage of the retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer and others. Besides this, Apidra 100IU /ml Injection can be safely prescribed to the diabetic mother during pregnancy and lactation.

• Injection site reactions (such as reddening, unusually intense pain on injection, itching, hives, swelling or inflammation)

• Hypoglycaemia (low blood sugar level)

• Hypokalaemia (low potassium)

• Lipodystrophy (fat deposition under the skin)

• Rash

• Pruritus (itchy skin)

Apidra 100IU /ml Injection is for subcutaneous (under the skin) in the abdominal wall, thigh, or upper arm. It can also be administered intravenously (IV) only with 0.9% saline solution infusion. If you are changing the brand of insulin or if you need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure were reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first symptoms of hyperglycaemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. If you have had any heart attack or have weight gain and oedema (fluid deposition in tissue), let your doctor know before taking Apidra 100IU /ml Injection. It is advisable not to consume alcohol as it may either increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. Apidra 100IU /ml Injection may decrease the level of potassium (hypokalemia) if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma and even death. Do not take Apidra 100IU /ml Injection if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug-Drug Interactions: Apidra 100IU /ml Injection may have an interaction with drugs that may increase the risk of antiarrhythmic (disopyramide), hemorheological agents (pentoxifylline), antidiabetic medicinal products (pramlintide, glucagon), beta-blockers (metoprolol), diuretics (furosemide ), bleeding disorder drugs (octreotide), antipsychotic (propoxyphene, phenothiazines), oestrogens, progestins (e.g. in oral contraceptives), protease inhibitors and atypical antipsychotic medicinal products (e.g. olanzapine and clozapine)., thyroid hormones (levothyroxine), anti-asthmatics (albuterol, epinephrine, terbutaline), antidepressant medications (fluoxetine, lithium), lipid-lowering pills (reserpine, niacin, clonidine, fenofibrate, guanethidine), pain killers (aspirin) and antibiotics (isoniazid).

Drug-Food Interactions: Apidra 100IU /ml Injection may interact with an ayurvedic, homoeopathy, Unani, herbal supplements or OTC items. Tell your doctor if you are using these products. Avoid drinking alcoholic beverages with Apidra 100IU /ml Injection as it may increase or decrease your blood sugar level.

Drug-Disease Interactions: Apidra 100IU /ml Injection should not be given to patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).

• ASPIRIN
• FUROSEMIDE
• METOPROLOL
• BUDESONIDE+FORMOTEROL

• Exercise may lower your body’s need for insulin during and sometimes after physical activity.

• Exercise may also speed up the effect of an insulin dose, especially if the exercise involves the area of the injection site (for example, the leg should not be used for injection just prior to running).

• Discuss with your doctor how to adjust your insulin regimen to accommodate exercise. 

• Avoid eating sugar food and prefer food cooked food low in calories.

• When travelling across more than two time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

• Your doctor may tell you to have a regular potassium level as prolonged administration causes a life-threatening condition of hypokalemia (low potassium). 

Diabetes: Diabetes is a chronic or lifelong disease that prevents the body from utilizing insulin properly. Insulin is the hormone that controls sugar levels in the blood. Diabetes is a condition in which blood glucose levels are above normal. It is of two types, namely: type-1 and type-2 diabetes. Type-1 diabetes is a condition in which the pancreas produces little or no insulin. Type-2 diabetes affects the way the body processes sugar. Symptoms of diabetes include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.