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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Anacin Multipain 400 mg/40 mg Tablet is used for the treatment of pain, headaches, muscle pain, minor arthritis pain, and fever or body pain caused by the common cold. It contains Aspirin and Caffeine, which work by inhibiting the production of prostaglandins (PGs) that cause swelling, inflammation, pain and fever. Also, it increases excitability in the brain, thereby relieves headache and enhances the effect of aspirin. Some people may experience side effects such as getting nervous and excitable, trouble sleeping, stomach pain, or heartburn, upset stomach or throwing up. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Pfizer Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Anacin Multipain 400 mg/40 mg Tablet

Anacin Multipain 400 mg/40 mg Tablet belongs to a group of medicines known as 'analgesics' mainly prescribed for the treatment of pain, headaches, muscle pain, minor arthritis pain, and fever or body pain caused by the common cold. Pain is a general term that describes the uncomfortable sensations in the body. The intensity of pain can range from annoying to debilitating, or a sharp stabbing or a dull ache. The possible causes of pain include headache, cramps, toothache, muscle strain or overuse, arthritis, stomach ache. 

Anacin Multipain 400 mg/40 mg Tablet contains two medicines, namely: Aspirin and Caffeine. Aspirin belongs to the category of salicylate that works by inhibiting the activity of the enzyme cyclooxygenase (COX) which forms prostaglandins (PGs) that cause swelling, inflammation, pain and fever. On the other hand, Caffeine is a stimulant that works by work by blocking the neurotransmitter known as adenosine, increasing excitability in the brain, thereby relieving headache and enhances the effect of aspirin.

Take Anacin Multipain 400 mg/40 mg Tablet with or without food with one glass of water. However, if stomach upset occurs, then take it with milk or food. Swallow the tablets as a whole without crushing or chewing the tablets as it can increase stomach upset. The doctor should suggest the dosage and length of treatment after checking your medical condition and response to treatment. Some persons may experience undesirable effects of Anacin Multipain 400 mg/40 mg Tablet that includes getting nervous and excitable, trouble sleeping, stomach pain, or heartburn, upset stomach or throwing up. However, not every person experiences these side effects or has minor side effects but if the unpleasant effects persist or worsen, then seek medical attention immediately.

If a person is allergic to Anacin Multipain 400 mg/40 mg Tablet or notices any allergic reaction like itching, peeling red skin, trouble breathing, then they need to talk to the doctor.  A person should limit the consumption of alcohol while taking Anacin Multipain 400 mg/40 mg Tablet as it may increase the risk of stomach/ gastric bleeding. This medicine is not advisable for children with flu, fever, or chickenpox unless the doctor has especially to them. This medicine is not allowed to use in late in pregnancy or last trimester in pregnancy as it may cause possible harm to the unborn baby and delay labour and childbirth. Anacin Multipain 400 mg/40 mg Tablet can cause Reye's syndrome (a rare but serious medical condition that causes swelling in the brain and liver, especially in children and teenagers). This medicine is not allowed to use in breastfeeding woman as it may harm the nursing infant and high doses of maternal aspirin after passing in breast milk could impair platelet function in the baby. 

Uses of Anacin Multipain 400 mg/40 mg Tablet

Treatment of Headache, Pain relief, Common cold.

Medicinal Benefits

Anacin Multipain 400 mg/40 mg Tablet is analgesic that is used to treat pain associated due to various conditions like menstrual cramps, headache, toothache, or muscle aches, fever, minor arthritis pain, and fever or body aches caused by the common cold and inflammation. In some cases, Anacin Multipain 400 mg/40 mg Tablet is also suggested to treat or prevent heart attacks, strokes, and chest pain (angina). If this medicine is using for cardiovascular conditions, then it should be used under the supervision of a doctor. When a body is hurt or infected, the body starts making hormones called prostaglandins. The release of prostaglandins is responsible for swelling, sometimes fever, and sending pain signals to the brain. Anacin Multipain 400 mg/40 mg Tablet works by blocking the activity of the cyclooxygenase (COX) and prostaglandins (PGs) that in turn lowers the pain and reduces swelling, inflammation, and fever.  

Directions for Use

Anacin Multipain 400 mg/40 mg Tablet should be taken with food and milk to avoid stomach upset. Swallow Anacin Multipain 400 mg/40 mg Tablet as a whole with a glass of water. Do not chew, crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Anacin Multipain 400 mg/40 mg Tablet

  • Upset stomach
  • Heartburn
  • Drowsiness
  • Mild headache

Drug Warnings

Anacin Multipain 400 mg/40 mg Tablet can cause ulcers and bleeding in your stomach or gut especially if taken for a longer duration so your doctor may suggest you not to take Anacin Multipain 400 mg/40 mg Tablet if you have a stomach ulcer or bleeding problems. Do not take in a bleeding disorder like haemophilia and if allergic to aspirin or caffeine or any other pain killers like ibuprofen. You should avoid drinking alcohol, taking pain killers, and the abortion pill (mifepristone) with Anacin Multipain 400 mg/40 mg Tablet as it may increase the risk of gastric bleeding and lower the effectiveness of the medication. Anacin Multipain 400 mg/40 mg Tablet should not be given in the children and teenagers as it may cause Reye's syndrome (a type of viral infection affecting brain and liver). Anacin Multipain 400 mg/40 mg Tablet has the ability to pass into breast milk and can harm the nursing infant, so consult with your doctor if you are breast-feeding mother before taking Anacin Multipain 400 mg/40 mg Tablet. The use of Anacin Multipain 400 mg/40 mg Tablet is strictly restricted in the last trimester of pregnancy as it can harm the unborn baby. Make sure that your laboratory personnel and doctors know that you are taking this medicine as it may interfere with laboratory tests like urine sugar tests, possibly causing false test results.

Drug Interactions

Drug-Drug Interaction: Like other medications,  Anacin Multipain 400 mg/40 mg Tablet could interact with other medications that include immune-related drugs (cyclosporin, tacrolimus), pain killers ( naproxen, ibuprofen), heart disease-related pills (acetazolamide, digoxin), the abortion pill (mifepristone),  blood thinners (warfarin, heparin, phenindione, clopidogrel),  anti-epilepsy drug (valproate, phenytoin), high blood pressure pills (captopril, metoprolol), an antidepressant (fluoxetine, sertraline, lithium), steroids, gout drug (probenecid), anti-cancer or anti-arthritis drug (methotrexate), anti-diabetic pills (glibenclamide), and osteoporosis-related drug (oral alendronate).

Drug-Food Interaction: Taking Anacin Multipain 400 mg/40 mg Tablet along with alcohol, caffeine, and herbal supplements like ‘Ginkgo Biloba’ can affect the working of Anacin Multipain 400 mg/40 mg Tablet and potentiate the side effect of this medicine.

Drug-Disease Interaction: Anacin Multipain 400 mg/40 mg Tablet should not be given in patients with blood clotting disorder (haemophilia), bleeding disorder, liver/kidney problem, stomach or intestinal ulcer, von willebrand's disease, asthma, severe heart problems which can cause shortness of breath.

Drug-Drug Interactions Checker List

  • NAPROXEN
  • CYCLOSPORINE
  • TACROLIMUS
  • IBUPROFEN
  • ACETAZOLAMIDE
  • DIGOXIN
  • MIFEPRESTONE
  • WARFARIN
  • HEPARIN
  • PHENINDIONE
  • CLOPIDOGREL
  • VALPROATE
  • PHENYTOIN
  • CAPTOPRIL
  • METOPROLOL
  • FLUOXETINE
  • SERTRALINE
  • LITHIUM
  • PROBENECID
  • METHOTREXATE
  • GLIBENCLAMIDE
  • ALENDRONATE SODIUM

Habit Forming

No

Diet & Lifestyle Advise

  • A person should take a low cholesterol diet along with a regular exercise regime as it will help the body to deal with pain in an efficient manner. 
  • The intake of alcohol with Anacin Multipain 400 mg/40 mg Tablet may increase the risk of gastrointestinal bleeding (stomach bleeding) so limit the consumption.
  • One should avoid consuming a high fatty meal and eat nutritious food so that body responds better to the medication. 
  • As a cautionary measure, it is suggested to avoid eating junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.
  • Practice relaxation techniques that help to calm down the mind and reduce pain levels.

Special Advise

  • Diagnostic tests like CT scan, MRI, and Myelogram can help in detecting the type of pain.
  • Use of Aspirin has been linked with Reye's syndrome (a viral infection causing liver and brain damage), so its use in children and teenagers should be done with caution for pain.

Disease/Condition Glossary

Pain describes uncomfortable sensations in the body that can range from sharp stabbing or a dull ache. It can be consistent, can start and stop frequently or happen under some medical conditions. Some of the common causes of pain include headache, cramps, muscle strain or overuse, cuts, arthritis, and stomach ache.  Acute pain usually starts suddenly, and go within days or weeks. However, if the pain is ongoing and lasts for more than 3 months, then it is said to be chronic. 

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Alcohol

Unsafe

The consumption of alcohol is strictly restricted with Anacin Multipain 400 mg/40 mg Tablet, as together it may potentiate unpleasant effects like stomach ulcer and gastric bleeding.

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Pregnancy

Unsafe

Consume only if strongly recommended by the doctor. This medicine is not allowed to use in late in pregnancy or the last trimester in pregnancy as it may cause possible harm to the unborn baby and delay labor and birth.

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Breast Feeding

Unsafe

Take Anacin Multipain 400 mg/40 mg Tablet only if prescribed by the doctor as it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Safe if prescribed

Anacin Multipain 400 mg/40 mg Tablet does not interfere with the thinking ability of a person so it is safer to drive after taking Anacin Multipain 400 mg/40 mg Tablet.

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Liver

Caution

Anacin Multipain 400 mg/40 mg Tablet is suggested to be taken with caution, especially if a person has a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Anacin Multipain 400 mg/40 mg Tablet is suggested to take with caution, especially if a person has a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Intake of Anacin Multipain 400 mg/40 mg Tablet is not allowed to use in children less than 3 years of age. However, it can be given to the children above 3 years of age if the doctor has prescribed it.

Country of origin

India
Other Info - AN32597

Author Details

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FAQs

Anacin Multipain 400 mg/40 mg Tablet is used for the treatment of pain, headaches, muscle pain, minor arthritis pain, and fever or body pain caused by the common cold.
When a person is hurt or has an infection, then the body starts making hormones called prostaglandins which are responsible for causing swelling, fever, inflammation in the body and send pain signals to the brain. This medicine works by blocking the activity of the cyclooxygenase (COX) and prostaglandins (PGs) that, in turn, lowers the pain and reduces swelling, inflammation, and fever.
Usually, a person starts noticing the pain-relieving effects of Anacin Multipain 400 mg/40 mg Tablet after 20 to 30 minutes of taking the medication.
It has been reported that if Anacin Multipain 400 mg/40 mg Tablet can cause ulcers in your stomach or gut especially if taken for a longer duration. Your doctor may suggest you not to take this medicine if you have a stomach ulcer, or if you've had one in the past.
Some people experience stomach upset problems after taking Anacin Multipain 400 mg/40 mg Tablet, so it is better to take this medicine with a meal or milk for better absorption of the medication.
It has been reported that in some conditions, Anacin Multipain 400 mg/40 mg Tablet is used for thinning of blood as it acts by preventing platelets (a type of blood cells) from sticking together and forming clots. Thus, a person should tell their doctor about their medical history or if any medicine they are taking.
This medicine is restricted to use in persons who have an active bleeding disorder such as haemophilia.
Anacin Multipain 400 mg/40 mg Tablet may cause Reye's syndrome that is a rare and serious disease that generally occurs in children if Anacin Multipain 400 mg/40 mg Tablet is given to treat a viral infection like smallpox, and chickenpox.
Anacin Multipain 400 mg/40 mg Tablet contains aspirin (a blood thinner) which might delay clotting time while surgery leading to excessive bleeding and blood loss. So, your doctor may ask you to stop taking Anacin Multipain 400 mg/40 mg Tablet before undergoing surgery.
A person should tell their doctor if they have a recent history of stomach or intestinal bleeding, active bleeding caused by haemophilia or another blood-clotting disorder, or hypersensitivity to an NSAID (a nonsteroidal anti-inflammatory drug) or pain killer. Anacin Multipain 400 mg/40 mg Tablet is contraindicated in these conditions.
If a person has asthma or has hay fever or any other chronic respiratory disease, then they should not take Anacin Multipain 400 mg/40 mg Tablet as it may induce an asthma attack and even worsen the condition.
Use of Anacin Multipain 400 mg/40 mg Tablet is not allowed in children and teenagers who have flu, chickenpox, or any undiagnosed illness. Additionally, if the child is vaccinated recently then asking Anacin Multipain 400 mg/40 mg Tablet might increase the risk of Reye's syndrome.

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