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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Ampitrust 3 gm Injection is used to treat several types of bacterial infections. It contains Ampicillin (a penicillin antibiotic) and Sulbactam (a beta-lactamase inhibitor). Ampicillin is a penicillin antibiotic that treats the infection by killing the bacteria. Sulbactam is a beta-lactamase inhibitor. It broadens the spectrum of antibacterial activity by inhibiting the action of beta-lactamase, an enzyme produced by bacteria that can destroy antibiotics.
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Prescription drug

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Manufacturer/Marketer

Fusion Health Care Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Ampitrust 3 gm Injection

Ampitrust 3 gm Injection belongs to a class of drugs called antibiotics used to treat several types of bacterial infections, including infections of the urinary tract, upper and lower respiratory tract, ears, nose, throat, chest, lungs, soft tissue, skin, bone and joint, intra-abdominal and gonococcal infections. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Ampitrust 3 gm Injection does not work against infections caused by the virus.

Ampitrust 3 gm Injection contains two antibiotics, Ampicillin (penicillin antibiotic) and Sulbactam (beta-lactamase inhibitor). Ampicillin works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. It damages the bacterial cell wall and kills bacteria. Sulbactam works by blocking beta-lactamase, an enzyme produced by bacteria to inactivate antibiotics. Thus, it prevents bacteria from destroying Ampicillin.

Ampitrust 3 gm Injection will be administered by a healthcare professional; do not self-administer. Sometimes, Ampitrust 3 gm Injection may cause common side effects such as pain at the injection site, diarrhoea, nausea or vomiting. Most of these side effects of Ampitrust 3 gm Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Ampicillin, Sulbactam, cephalosporin antibiotics, penicillin antibiotics, or any other medicines. If you are pregnant or breastfeeding, please inform your doctor before receiving Ampitrust 3 gm Injection. Ampicillin may reduce the effectiveness of birth control pills. Therefore, discuss with your doctor about other contraceptive methods to avoid pregnancy while on treatment with Ampitrust 3 gm Injection. If you have or have ever had liver disease, especially after using a penicillin antibiotic, inform your doctor before receiving Ampitrust 3 gm Injection. 

Uses of Ampitrust 3 gm Injection

Treatment of Bacterial infections

Medicinal Benefits

Ampitrust 3 gm Injection is a combination of two antibiotics: Ampicillin and Sulbactam, used to treat several bacterial infections. Ampitrust 3 gm Injection has a broad spectrum of antibacterial activity that acts against aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. Ampicillin interferes with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. It damages the bacterial cell wall and kills bacteria. Sulbactam blocks beta-lactamase, an enzyme produced by bacteria to inactivate antibiotics. Thus, it prevents bacteria from destroying Ampicillin.

Directions for Use

Ampitrust 3 gm Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ampitrust 3 gm Injection

  • Pain at the injection site
  • Diarrhoea
  • Nausea
  • Vomiting

Drug Warnings

Please tell your doctor if you are allergic to ampicillin, sulbactam, cephalosporin antibiotics, penicillin antibiotics, or any other medicines. If you are pregnant or breastfeeding, please inform your doctor before receiving Ampitrust 3 gm Injection. Ampicillin may reduce the effectiveness of birth control pills. Therefore, discuss with your doctor about other contraceptive methods to avoid pregnancy while on treatment with Ampitrust 3 gm Injection. If you have or have ever had liver disease, especially after using a penicillin antibiotic, inform your doctor before receiving Ampitrust 3 gm Injection. Ampitrust 3 gm Injection may interact with specific tests such as glucose (sugar) in urine and give false positive results. Therefore, inform the doctor that you are on treatment with Ampitrust 3 gm Injection before undergoing any tests.

Drug Interactions

Drug-Drug Interaction: Inform your doctor if you are taking medicines used to treat gout (probenecid, allopurinol), anticancer drugs (methotrexate), aminoglycosides, anticoagulants (blood thinners), antibiotics (erythromycin, sulphonamides, chloramphenicol, tetracyclines), or estrogen-containing oral contraceptives.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have mononucleosis (a contagious disease), have or have ever had liver disease, allergies, hay fever, asthma, hives or kidney disease, inform your doctor before receiving Ampitrust 3 gm Injection.

Drug-Drug Interactions Checker List

  • PROBENECID
  • ALLOPURINOL
  • METHOTREXATE
  • ERYTHROMYCIN
  • CHLORAMPHENICOL

Habit Forming

No

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Ampitrust 3 gm Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can help restore the intestine's good bacteria.
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids daily while you are receiving Ampitrust 3 gm Injection.
  • Avoid alcohol consumption as it may increase adverse effects.

Special Advise

  • If you are about to undergo any urine tests, inform your doctor or lab technician that you are on treatment with Ampitrust 3 gm Injection as it may interfere with these tests giving false positive results.

Disease/Condition Glossary

Bacterial infection: It is a condition in which harmful bacteria grow in the body and causes infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes: spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness.

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Alcohol

Consult your doctor

The interaction of Ampitrust 3 gm Injection with alcohol is unknown. If you have any concerns, please discuss them with your doctor.

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Pregnancy

Consult your doctor

Limited data is available on the effect of Ampitrust 3 gm Injection in pregnancy. Hence, if you are pregnant or planning for pregnancy, inform your doctor before receiving Ampitrust 3 gm Injection. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Caution

Low concentrations of Ampitrust 3 gm Injection may be excreted in breast milk. Therefore, Ampitrust 3 gm Injection should be used with caution if you are breastfeeding.

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Driving

Caution

It is unknown whether Ampitrust 3 gm Injection affects your ability to drive. However, avoid driving if you experience any symptoms affecting your driving ability.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Ampitrust 3 gm Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Ampitrust 3 gm Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

The safety and effectiveness of Ampitrust 3 gm Injection in children aged one year and above have been established. However, it is administered by a doctor or nurse.

Country of origin

India

Manufacturer/Marketer address

Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
Other Info - AMP0209

Author Details

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FAQs

Ampitrust 3 gm Injection is used to treat Bacterial infections.
Ampitrust 3 gm Injection is a combination of two antibiotics: Ampicillin and Sulbactam. Ampicillin works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. It damages the bacterial cell wall and kills bacteria. Sulbactam works by blocking beta-lactamase, an enzyme produced by bacteria to inactivate antibiotics. Thus, it prevents bacteria from destroying Ampicillin.
Ampitrust 3 gm Injection may be used to treat pneumonia (lung infection) caused by bacteria. Ampitrust 3 gm Injection is an antibiotic that kills bacteria and prevents the spread of infection. But it should be used only when prescribed by a doctor.
Ampitrust 3 gm Injection may cause diarrhoea as a common side effect. However, if the condition persists or worsens, or you notice blood or mucus in your stools, inform your doctor immediately.
Ampicillin in Ampitrust 3 gm Injection may reduce the effectiveness of oral contraceptives. Therefore, you may be advised to use an alternate or additional method of contraception while on treatment with Ampitrust 3 gm Injection. However, please consult your doctor before using other medicines with Ampitrust 3 gm Injection.

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