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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:25 PM IST
Amphocil 100mg Injection is used to treat severe fungal infections. It contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. In some cases, this medicine may cause side effects such as fever, chills, nausea, vomiting, headache, muscle cramps or pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Synonym

LIPOSOMAL AMPHOTERICIN B

Manufacturer/Marketer

Criticare Laboratories Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Amphocil 100mg Injection

Amphocil 100mg Injection belongs to a class of medication called 'antifungal' used to treat severe fungal infections like leishmaniasis. A fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. 

Amphocil 100mg Injection contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.

Amphocil 100mg Injection is given by a doctor or nurse. In some cases, you may experience fever, chills, irregular heartbeat, high or low blood pressure, breathing problems, nausea, vomiting, headache, shaking, muscle cramps or pain. Most of these side effects of Amphocil 100mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Amphocil 100mg Injection or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Amphocil 100mg Injection. Amphocil 100mg Injection is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Amphocil 100mg Injection as it may affect your ability to drive. If you experience severe adverse effects such as chest pain or difficulty in breathing, or encephalopathy (a brain disease which may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help.

Uses of Amphocil 100mg Injection

Treatment of Severe fungal infections

Medicinal Benefits

Amphocil 100mg Injection contains Amphotericin B, an antifungal used to treat severe fungal infections. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Amphocil 100mg Injection damages fungal cell membranes and kills fungi. Amphocil 100mg Injection is used to treat infections such as blood infection with candida, cryptococcus, fusarium, zygomycetes, aspergillus, coccidiodes or blastomycetes, or cryptococcal meningitis (inflammation of the brain).

Directions for Use

Amphocil 100mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Amphocil 100mg Injection

  • Fever

  • Chills
  • Irregular heartbeat
  • High or low blood pressure
  • Breathing problems
  • Nausea
  • Vomiting
  • Headache
  • Shaking
  • Muscle cramps or pain

Drug Warnings

If you are allergic to Amphotericin B or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Amphocil 100mg Injection. Amphocil 100mg Injection is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Amphocil 100mg Injection as it may affect your ability to drive. If you experience severe adverse effects such as chest pain, difficulty breathing, or encephalopathy (a brain disease that may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help. If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking Amphocil 100mg Injection.

Drug Interactions

Drug-Drug Interaction: Amphocil 100mg Injection may interact with an anti-HIV drug (zidovudine), immunosuppressant (ciclosporin), antifungal (flucytosine), water pills (furosemide), anticancer drug (methotrexate).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking Amphocil 100mg Injection.

Drug-Drug Interactions Checker List

  • ZIDOVUDINE
  • CICLOSPORIN
  • FLUCYTOSINE
  • FUROSEMIDE
  • METHOTREXATE

Habit Forming

No

Diet & Lifestyle Advise

  • Wash your hands regularly and keep your hands clean to prevent the spread of germs.

  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt and long pants while doing outdoor activities such as yard work, gardening or visiting wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Special Advise

  • Regular blood tests are recommended while taking Amphocil 100mg Injection to monitor blood, liver or kidney functioning and potassium levels.

Disease/Condition Glossary

Fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. Cryptococcal meningitis is a fungal infection of tissues covering the spinal cord (meninges) and brain. The symptoms include headache, hallucinations, fever, stiff neck, sensitivity to light, nausea and vomiting. Fungal infections in the lungs may be more serious and life-threatening and often cause symptoms similar to tuberculosis or bacterial pneumonia.

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Alcohol

Caution

The interaction of Amphocil 100mg Injection with alcohol is unknown. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Consult your doctor

Amphocil 100mg Injection is a Category B pregnancy drug and is given to a pregnant woman if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning pregnancy.

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Breast Feeding

Consult your doctor

It is unknown whether Amphocil 100mg Injection is excreted in human milk. If you are breastfeeding, inform your doctor before receiving this injection.

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Driving

Caution

Avoid driving after taking Amphocil 100mg Injection as it may affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Inform your doctor if you have a history of liver diseases/conditions before receiving Amphocil 100mg Injection.

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Kidney

Consult your doctor

Inform your doctor if you have a history of kidney diseases/conditions before receiving Amphocil 100mg Injection.

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Children

Caution

Amphocil 100mg Injection is not recommended for children below one month as the safety and effectiveness were not established.

Country of origin

India
Other Info - AM90583

Author Details

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FAQs

Amphocil 100mg Injection is used to treat severe fungal infections like leishmaniasis.
Amphocil 100mg Injection contains Amphotericin B, an antifungal that works by damaging fungal cell membranes, thereby killing fungi.
You are not recommended to take Amphocil 100mg Injection with furosemide as co-administration of these medicines may increase the risk of hypokalaemia (low potassium levels in the blood), and in severe cases, it may lead to paralysis, muscle weakness, irregular heart rhythm, difficulty in breathing or swallowing. However, please consult your doctor before taking Amphocil 100mg Injection with other medicines.
Amphocil 100mg Injection may cause blue lips and skin, probably during infusion or in the initial 2 days of treatment. However, your doctor or nurse may arrange certain simple treatments to control such adverse effects.
Yes, a test dose of Amphocil 100mg Injection may be given in smaller amounts before starting the treatment to check if you are sensitive to any of the ingredients.
You are recommended to use Amphocil 100mg Injection for as long as your doctor has prescribed it. However, the usual treatment is for a minimum of 14 days. Please consult a doctor if you experience any difficulty while taking Amphocil 100mg Injection.
Amphocil 100mg Injection is not used to treat viral infections. Amphocil 100mg Injection is an antifungal that kills fungi and is used to treat severe fungal infections.
Amphocil 100mg Injection is an antifungal medication used to treat severe fungal infections like leishmaniasis. It kills fungi by destroying the fungal outer cell membrane.
Amphocil 100mg Injection will be administered intravenously by a healthcare professional; do not self-administer.
Amphocil 100mg Injection is fungicidal in nature, it works by killing the infection-causing fungus.
Inform the doctor if you are allergic to any of the components in Amphocil 100mg Injection or if you experience allergic reactions during treatment with Amphocil 100mg Injection. Let the doctor know if you have kidney problems, diabetes, or if you are taking any other medicines.
Amphocil 100mg Injection is an antifungal medication used to treat severe fungal infections like leishmaniasis
Amphocil 100mg Injection may cause side effects like fever, chills, nausea, vomiting, headache, muscle cramps or pain. Most of these side effects of Amphocil 100mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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